antihistamine question

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Veteran Member

Date Joined Nov 2009
Total Posts : 7270
   Posted 4/13/2010 11:16 PM (GMT -6)   
OK, maybe I finally have a little benefit from my PC.
For years I had BPH. Flomax worked great. Without it, I would have difficulty urinating.
Antihistamines were a big no-no; they caused lots of problems and even the label warned against taking them if you have enlarged prostate symptoms.
Anyway, I now have a miserable sinus infection and/or cold since Friday and I'll be seeing the doctor tomorrow. But, meanwhile, I'm going to take a benedryl or similar item.
Correct? Anyone else in that boat (ie: unable to take antihistamine before surgery but now using it)

63 years old . PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (Free PSA 24%),  after 45 days on cipro! DREs have always been normal. PCA-3 was about 75 (way above the 35 threshold). That led to:

Biopsy on 11/30/09. 5 out of 12 cores positive. Gleason 4+3. 2 cores were 3+3 (one 5% and the other 30%) on one side. On  other side:2 cores are 4+3 (5%)--1 core 3+4 (30%) no peri-neural invasion. prostate is 45 grams. Stage: T1C.  

Surgery with Dr. Menon at Ford Hospital, 1/26/10. He says all looked good. Spared nerves. Unfortunately: Pathology Report: G 4+3 (65%-35%). Cancer in 15% of gland. Lymph Nodes: Clear.  Perineural Invasion: yes. Seminal Vessical Involvement: No.  Extraprostatic Extension: yes.  Positive Margin: Yes-- focal-- 1 spot .5mm. Final Weight is 52.7 gms.  (Second opinion from Jon Epstein at Hopkins confirmed these results)

 Incontinence: joined that club-- definite leaks—1 pad/day. Night is dry, was  using 1 pad at night for security, but pretty much dispensed with that most nights. Update: no pads at night. No pads while at home, but still very uncomfortable. Use 1 pad for out-of-house activities. Suddenly got MUCH better on 3/10/10, almost overnight. Still some urgency but no pads about 90% of the time.  As of 3/12/10--completely continent! Uh...OH. As of about 3/16/10 problems with constant urgency although no pads needed--feels like an infection but none showing in urine.

First post-op PSA on 3/10/10--DRUM ROLL: 0.01 Next PSA in mid-June.

Cajun Jeff
Veteran Member

Date Joined Mar 2009
Total Posts : 4119
   Posted 4/13/2010 11:19 PM (GMT -6)   

Mel,  You are correct with you thinking.   Could not take antihistamines after surgery  no problem.  Give it a try.

Cajun Jeff

9/08 PSA 5.4 referred to Urologist
9/08 Biopsy: GS 3+4=7 1 positive core in 12 1 pre cancer core
10/08 Nerve-Sparing open radical
Surgery Path Report Downgrade 3+3=6 GS Stage pT2c margins clear

3 month: PSA <0.1
6 month: PSA <0.1
10 month:PSA <0.1
1 year: PSA <0.1
16 month:PSA <0.1

ED - Started Cialis at 3 months, tried all 3, 6 months added pump, 9 months Tried MUSE (YUCK) Bad experience.
1 year mark Found new Urologist visit was at 14th month post surgery
Started Injections, Caverject! (Success)
17 month: ED making improvements : Oral Meds gets me 85%

Veteran Member

Date Joined Jul 2009
Total Posts : 504
   Posted 4/14/2010 6:52 AM (GMT -6)   
Hi Mel,

Perhaps you could give Sudafed ( behind the counter version, not PE version) a try, it contains Pseudeophedrine which for me works great when I need to get rid of nasal congestion. It also happens to be the antidote in case Trimix/Bimix erection last over 4 hrs ( never had that happen ,,so far)
Age: 52, PSA (2008)=1.9
Biopsy on 01/09/09, Gleason Score = 3+3
One (1) out of twelve (12) cores was positive, plus external nodule found
Surgery (Da Vinci, robotic prostatectomy): 4/7/09
Post Op Path 3+3
Removed Catheter: 04/19/09
100% bladder control - Pad free 7/09
PSA 7/09 undetectable, <0.01 - 3 months post-op
PSA 1/10 undetectable, <0.01 - 9 months post-op
Trimix provides 100% erectile function

Regular Member

Date Joined Apr 2009
Total Posts : 179
   Posted 4/14/2010 1:59 PM (GMT -6)   
I couldn't take antihistamines prior to my RRP but now they are no problem what so ever.
63 yo
V10.46 Dx Feb-09

RRP 5-5-09

No adverse SE

PSA 6-19-09 -0-

PSA 9-21-09 -0-

Thriving, not just surviving!

Regular Member

Date Joined Oct 2009
Total Posts : 171
   Posted 4/14/2010 2:12 PM (GMT -6)   
The Sudafed also might help with incontinence since it will tighten up the external sphincter.


Regular Member

Date Joined Jan 2010
Total Posts : 281
   Posted 4/14/2010 3:51 PM (GMT -6)   
Although the label plainly stated that the antihistimine (WalMart version of Claratin) should not be used if there is a problem of enlarged prostate, my allergies were going nutz and the nose would not stop dripping, so I used the anthihistime anyhow. Wow, really slowed down the ability to pee to almost a total stop. Although I'm still in possession of a big ole prostate and still waiting for my Brachytherapy procedure still a month away, I called my Uro and he told me to use ONLY a nose spray. So, I took some Zicam nasal spray and it worked like a charm. Worked for me anyhow.
Bob, down in Southern Colorado

Veteran Member

Date Joined Sep 2009
Total Posts : 6084
   Posted 4/16/2010 6:34 PM (GMT -6)   
I take 1 benedryl whenever I have trouble sleeping, works for me!!
age 66 First psa 4/17/09 psa 8.3, 7/27/09 psa 8.1
8/12/09 biopsy 6 out of 12 pos 2-70%, rest <5% 3+3
10/19/09 open rrp U of W Medical Center, left bundle spared
10/30/09 catheter out. continent from the jump.
pathology- prostate confined, only thing positive was the report.everything else negative
9% of prostate affected. gleason 3+4, I suppose thats a negative
After reading pathology myself, gleason was 3+4 with tertiary 5, 2-3 foci That is a negative, but I am a positive !!
Ed an issue but keeping the blood flowing with the osbon pump
8 week psa 0,o

" Hypocrisy is vice's homage to Virtue " read it in Bartlet's book of quotation years ago stuck with me, can't remember who said it.

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