Enlarged Prostate Normal PSA

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New Member

Date Joined Apr 2010
Total Posts : 2
   Posted 4/21/2010 12:26 PM (GMT -6)   
My dad who is 56 visited the urologist last week and was told he has an enlarged prostate.  A psa test was done the same day, the level was 0.2.  Urine specimen was great.  My question, can you have an enlarged psa and a normal or low psa?  Should I be concerned about cancer?

Regular Member

Date Joined Mar 2010
Total Posts : 78
   Posted 4/21/2010 1:40 PM (GMT -6)   
Good news for your Dad:  enlarge prostate has nothing to do with PC

Veteran Member

Date Joined Sep 2009
Total Posts : 3172
   Posted 4/21/2010 1:56 PM (GMT -6)   
daddynat said...
My question, can you have an enlarged psa and a normal or low psa? 
I think you meant to ask:  "Can you have an enlarged prostate and normal or low PSA?"
Answer:  yes
An enlarged prostate may be caused by PC (despite earlier response), but that's a great PSA result, which indicates the greatest likelihood of a non-cancerous cause of the enlargement (and possible symptoms, which you didn't mention).  BPH is common, and so to learn more, I would suggest Googling "BPH".
By the way, welcome to the site...

John T
Veteran Member

Date Joined Nov 2008
Total Posts : 4269
   Posted 4/21/2010 2:14 PM (GMT -6)   
Multiply the estimated size of the prostate in cc X .066 and you will get the amount of psa that should be produced.

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.


New Member

Date Joined Apr 2010
Total Posts : 2
   Posted 4/21/2010 2:34 PM (GMT -6)   
Thanks for the input guys. The urologist wasn't that concerned to begin with. I had conflicting info in regards to an enlarged prostate and a higher than normal psa. I was concerned that my Dad's psa was too low for an enlarged prostate. I've read on numerous web sites that enlarged prostates produce higher psa levels. Haven't seen much about an enlarged prostate and a normal or low psa number. I hope I have nothing to worry about.

New Member

Date Joined Mar 2010
Total Posts : 3
   Posted 5/12/2010 2:18 AM (GMT -6)   
I’m glad to hear your dad is fine. My dad had a prostate exam about 6 months ago. The doctor said that there was a slight growth of the prostate gland, but there was nothing to worry about. I was concerned, though, and began to study more about prostate health. I learned that the prostate gland keeps growing the entire lifespan of a man. But at around 50 it can become so big that it begins to push the urethra, disturbing urinary functions and flow. (My dad used to get up many times during the night.) I also read a lot about beta sitosterol, a natural nutrient that has been used extensively for supporting prostate health. I asked the doctor about this and he said it was fine for my dad to take it. He’s taking a prostate supplement called Super Beta Prostate. It seems to be working since he doesn’t get up in the nights at all these days. He’s due for another check up in a few months. You might want to ask your dad’s doctor about beta sitosterol.

Regular Member

Date Joined Mar 2010
Total Posts : 34
   Posted 5/12/2010 8:34 AM (GMT -6)   
I've had a moderately enlarged prostate and mild BPH for about 10 years and my PSA has always been between 0.75 and 0.82, at least from the 5 or 6 readings that I have at home. It has not gotten worse or better in that time, except that I started to take doxazosin last year and my BPH has greatly improved. I'm currently 65 years old.
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