anyone that has had an experience with brachytherapy and radiation.? Was No Subject

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ridgewalker
New Member


Date Joined Mar 2010
Total Posts : 7
   Posted Today 6:11 AM (GMT -6)   
I would like to hear from anyone that has had an experience with brachytherapy and radiation.

What short term and long side effects have you experienced?

How long before You are able to resume normal functioning?

What size should prostate be?

65 years

gleason 3+4=7

psa 6.1

1 positive of 20 core samples

20%

diagnose 2/18/10

perineural invasion identified

bone scan negative



Added a Subject for archiving and searching

Post Edited By Moderator (James C.) : 4/22/2010 8:03:24 AM (GMT-6)


Tudpock18
Forum Moderator


Date Joined Sep 2008
Total Posts : 4083
   Posted Today 7:31 AM (GMT -6)   

Dear Ridge:

There are several active posters who have had brachytherapy and/or other experience with radiation as a primary treatment.  You can select the link in my signature to see a fairly detailed version of my "journey".  In answer to your specific questions:

1. The short term side effects for me were some urgency and frequency of urination.  Those effects were mild, lasted less than three months and were easily controlled with Flomax and by avoiding caffeine, alcohol and spicy food for those three months.  I also didn't have sex for two weeks after the procedure.

2.  I am 1 1/2 years post treatment with no further side effects.

3.  I returned to normal functioning in a day or so.  The procedure in non-invasive and done on an outpatient basis.  For me, the catheter was gone before I woke up.

4.  Recommended prostate size for brachytherapy is 50cc or smaller.  HT can reduce the prostate size pre-procedure if necessary.

Hope this helps.  Please let me know if you need additional info.

Tudpock


Age 62, Gleason 3 + 4 = 7, T1C, PSA 4.2, 2 of 16 cores cancerous, 27cc
Brachytherapy December 9, 2008.  73 Iodine-125 seeds.  Procedure went great, catheter out before I went home, only minor discomfort.  Regular activities resumed, everything continues to function normally as of 4/10/10.  6 month PSA 1.4 and now 1 year PSA at 1.0.  My docs are "delighted"!

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4188
   Posted Today 10:17 AM (GMT -6)   
Ridgewalker,
I had Brachy about a year ago followed 6 weeks later by 25 sessions of IMRT. I was able to function normally after one day. Had urinary frequency and urgency for 4 weeks that didn't affect normal activities. No affects at all with the IMRT sessions. I have experienced no side affects from the treatments.
The smaller your prostate is the better the radiation works and the less side affects. It can be reduced about 50% with 3 months of Casodex and proscar. Mine went from 60cc to 32 cc.
There was a recent article about stranded seeds vs loose seeds indicating that stranded seeds are much less effective than loose seeds in delivering the radiation dose.
If you have any specific questions post them and Tud and I will try to answer them. The key is to get a brachytherapist that is well experienced, at least 500 procedures.
JohnT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


Tudpock18
Forum Moderator


Date Joined Sep 2008
Total Posts : 4083
   Posted Today 12:19 PM (GMT -6)   

JT...I missed the article re stranded seeds vs. loose.  Mine were stranded so if you could provide a link I would appreciate it so I can challenge it with my radiation doc...not that it changes anything for me, but he loves a good debate and I'll be interested in what he says...

Thanks,

Tud


Age 62, Gleason 3 + 4 = 7, T1C, PSA 4.2, 2 of 16 cores cancerous, 27cc
Brachytherapy December 9, 2008.  73 Iodine-125 seeds.  Procedure went great, catheter out before I went home, only minor discomfort.  Regular activities resumed, everything continues to function normally as of 4/10/10.  6 month PSA 1.4 and now 1 year PSA at 1.0.  My docs are "delighted"!

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4188
   Posted Today 2:47 PM (GMT -6)   
Tud,

http://prostatecancerinfolink.net/2010/04/21/loose-and-stranded-seeds-and-brachytherapy-outcomes/

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT

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