Weight Gain after Pca Surgery doubles recurrence risk

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Sunbird
Regular Member


Date Joined Apr 2008
Total Posts : 140
   Posted 4/23/2010 6:00 PM (GMT -6)   
From Cancer News, www.melindia.net dtd 4-21-10,
 
"Johns Hopkins epidemiologists warn that weight gain (about five or more lbs.) near prostate cancer surgery time doubles the risk of prostate cancer recurrence as compared to patients whose weight remains stable."
 
"The good news is that being physically active reduced the risk of recurrence associated with obesity, says Elizabeth Platz, Sc.D., M.P.H. associate professor at the Johns Hopkins Bloomberg School of Public Health"
 
I hope everybody is walking, jogging, or riding their bicycles............
1996, Age 48, Stage III Colon Ca, Colon Resection followed by 18 chemo treatments.
 
2000, Colon Ca Metastasis to upper left lung lobe.  Lung lobe surgically removed.  24 chemo treatments scheduled.  Took 1, declined the rest.
 
9/08 PSA is 2.8, 12/08 PSA is 4.56??  Chalk it up to prostatitis due to urinary retention after Nissen Fundo Surgery.  VA docs prescribe 30 days of Septra.  Prostate feels normal.  PSA hovers around 4.1.  VA docs want prostate biopsy but can't seem to get me into the schedule.  Continue through Spring and Fall of 2009 thinking I have prostatitis.  Bacteria cultures are always neg.  PSA drops to 3.1 10/09.
 
12/09 Prostate Biopsy performed
3 of 10 cores positive, 5%, 25%, & 35%, 3 + 3= Gleason Six with perineural invasion.
 
Doc wants CT Scan due to prior Colon Ca. Findings: "The seminal vesicles are irregular & there is nodularity in the periprostatic fat such that local extension cannot be excluded.  Shotty lymph nodes in both groin measuring 2.3 cm."
 
Doc wants Endo-rectal MRI (OUCH!) Findings: Mild central zone BPH, no discrete focus of carcinoma is identified, no evidience of invasion into the periprostatic fat or seminal vesicles.  Normal size iliac chain lymph nodes.
 
2/08/10 Open RP surgery.  Findings: Gleason Six upgraded to Seven.  3 + 4, Stage pT2c, Bilateral w/perineural invasion, No pos lymph nodes,  margins uninvolved, no extraprostatic extension, no seminal vesicle extension,  39 grams, blood loss 1200 ml (didn't want a transfusion & didn't get one) nerve bundles spared bilaterally.  current age-61


Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3743
   Posted 4/23/2010 7:45 PM (GMT -6)   
Ummm... Does running to the bathroom count? I do that a lot.
Here's a safety tip for you: Never stand between me and the porcelain.
Jeff

goodlife
Veteran Member


Date Joined May 2009
Total Posts : 2692
   Posted 4/23/2010 10:27 PM (GMT -6)   
I must admit to finding these statements dubious. The website doesn't work, so I guess I will have to wait and see.

I see no logic to 5 pounds of weight and reoccurence of cancer. If one has a successful removal of a cancerous prosate with negative margins, etc. how could adding 5 pounds affect it ?

Maybe it is an inverse realtionship. Those who still have cancer cells are prone to gain wait.
Goodlife
 
Age 58, PSA 4.47 Biopsy - 2/12 cores , Gleason 4 + 5 = 9
Da Vinci, Cleveland Clinic  4/14/09   Nerves spared, but carved up a little.
0/23 lymph nodes involved  pT3a NO MX
Catheter and 2 stints in ureters for 2 weeks .
Neg Margins, bladder neck negative
Living the Good Life, cancer free  6 week PSA  <.03
3 month PSA <.01 (different lab)
5 month PSA <.03 (undetectable)
6 Month PSA <.01
1 pad a day, no progress on ED.  Trimix injection
No pads, 1/1/10,  9 month PSA < .01
1 year psa (364 days) .01


Sleepless09
Veteran Member


Date Joined Jul 2009
Total Posts : 1267
   Posted 4/23/2010 10:45 PM (GMT -6)   
Sure makes me glad I lost 10 pounds before my surgery.

But ..... not so happy that in the last 9 months I've put fifteen back on.

Hmmmmm????


Sheldon AKA Sleepless
Age 67 in Apil '09 at news of 4 of 12 cores positive T2B and Gleason 3 + 3 and 5% to 25% PSA 1.5
Re-read of slides in June said Gleason 3 + 4 same four cores 5% to 15%
June 29 daVinci prostatectomy, Dr. Eric Estey, at Royal Alexandra Hospital Edmonton one night stay
From "knock out" to wake up in recovery less than two hours.  Actual surgery 70 minutes
Flew home to Winnipeg on July 3 after 5 nights in Ramada Inn  ---  perfect recovery spot!
Catheter out July 9
Final pathology is 3 + 4 Gleason 7, clear margins, clear nodes, T2C, sugeron says report is "excellent"
 
Oct 1st 09 -- dry at night, during day some stress issues.
Oct 31st padless 24/7 
 
First post op PSA Sept 09  less than 0.02
PSA on Oct 23 test again less than 0.02
PSA on Jan 8 less than 0.02
PSA on April 9 less than 0.02 
 
  


Sunbird
Regular Member


Date Joined Apr 2008
Total Posts : 140
   Posted 4/24/2010 7:58 AM (GMT -6)   
ok...www.medindia.net or just google "weight gain after Prostate Cancer Surgery doubles recurrence risk" to find quite a few links.........
1996, Age 48, Stage III Colon Ca, Colon Resection followed by 18 chemo treatments.
 
2000, Colon Ca Metastasis to upper left lung lobe.  Lung lobe surgically removed.  24 chemo treatments scheduled.  Took 1, declined the rest.
 
9/08 PSA is 2.8, 12/08 PSA is 4.56??  Chalk it up to prostatitis due to urinary retention after Nissen Fundo Surgery.  VA docs prescribe 30 days of Septra.  Prostate feels normal.  PSA hovers around 4.1.  VA docs want prostate biopsy but can't seem to get me into the schedule.  Continue through Spring and Fall of 2009 thinking I have prostatitis.  Bacteria cultures are always neg.  PSA drops to 3.1 10/09.
 
12/09 Prostate Biopsy performed
3 of 10 cores positive, 5%, 25%, & 35%, 3 + 3= Gleason Six with perineural invasion.
 
Doc wants CT Scan due to prior Colon Ca. Findings: "The seminal vesicles are irregular & there is nodularity in the periprostatic fat such that local extension cannot be excluded.  Shotty lymph nodes in both groin measuring 2.3 cm."
 
Doc wants Endo-rectal MRI (OUCH!) Findings: Mild central zone BPH, no discrete focus of carcinoma is identified, no evidience of invasion into the periprostatic fat or seminal vesicles.  Normal size iliac chain lymph nodes.
 
2/08/10 Open RP surgery.  Findings: Gleason Six upgraded to Seven.  3 + 4, Stage pT2c, Bilateral w/perineural invasion, No pos lymph nodes,  margins uninvolved, no extraprostatic extension, no seminal vesicle extension,  39 grams, blood loss 1200 ml (didn't want a transfusion & didn't get one) nerve bundles spared bilaterally.  current age-61


Zen9
Regular Member


Date Joined Oct 2009
Total Posts : 314
   Posted 4/24/2010 9:33 AM (GMT -6)   
Don't believe everything you read. There's a lot of BS out there about PCa, and doctors are behind much of it.

Zen9

Sleepless09
Veteran Member


Date Joined Jul 2009
Total Posts : 1267
   Posted 4/24/2010 10:03 AM (GMT -6)   
Alright, I went to medindia.net and couldn't find the information on increased risk with weight gain. I take this as a sign from God that it doesn't apply to me.
 
On the other hand, if I accept that logic, then what do I think of this article in the men's section: "Luxurious Beer Bellies Prevent Aussie Men From Viewing Private Parts.  One in three Aussie men, a survey has revealed, can't view their own private parts when they look down."

(For those of you who are so inclined: Read more: MenĀ“s Health News http://www.medindia.net/healthnews/Mens-Health-News.asp?page=3&startpage=1#ixzz0m1ipW4Jg)

The site also informed me that: "Half of Aussie Men Would Get Their Willies Enlarged: Survey. If the findings of a new survey are to be believed, half of Aussie men would love to get their willies enlarged."

Why would the findings not be believed? I mean, if a third can't see it in the first place no wonder a little extra in the private part department woiuld be welcome.

Lest you think the site is totally focused on Aussie Willies, this is not the case. On the front page of the site I was greeted with the headline that "Unprotected anal sex most common among Asian women in US."

Perhaps if delved further into the site I'd find the information on weight gain and PCa but I was so puzzled as to what to make of the information I'd already gleaned from the site my stress level had reached the point I needed a bowl of ice cream to settle my nerves. Nothing like ice cream for breakfast!

Sheldon AKA Sleepless






Age 67 in Apil '09 at news of 4 of 12 cores positive T2B and Gleason 3 + 3 and 5% to 25% PSA 1.5
Re-read of slides in June said Gleason 3 + 4 same four cores 5% to 15%
June 29 daVinci prostatectomy, Dr. Eric Estey, at Royal Alexandra Hospital Edmonton one night stay
From "knock out" to wake up in recovery less than two hours.  Actual surgery 70 minutes
Flew home to Winnipeg on July 3 after 5 nights in Ramada Inn  ---  perfect recovery spot!
Catheter out July 9
Final pathology is 3 + 4 Gleason 7, clear margins, clear nodes, T2C, sugeron says report is "excellent"
 
Oct 1st 09 -- dry at night, during day some stress issues.
Oct 31st padless 24/7 
 
First post op PSA Sept 09  less than 0.02
PSA on Oct 23 test again less than 0.02
PSA on Jan 8 less than 0.02
PSA on April 9 less than 0.02 
 
  

Post Edited (Sleepless09) : 4/24/2010 9:06:28 AM (GMT-6)


goodlife
Veteran Member


Date Joined May 2009
Total Posts : 2692
   Posted 4/24/2010 11:59 AM (GMT -6)   
Sheldon,

Thanks for my laugh for the day !
Goodlife
 
Age 58, PSA 4.47 Biopsy - 2/12 cores , Gleason 4 + 5 = 9
Da Vinci, Cleveland Clinic  4/14/09   Nerves spared, but carved up a little.
0/23 lymph nodes involved  pT3a NO MX
Catheter and 2 stints in ureters for 2 weeks .
Neg Margins, bladder neck negative
Living the Good Life, cancer free  6 week PSA  <.03
3 month PSA <.01 (different lab)
5 month PSA <.03 (undetectable)
6 Month PSA <.01
1 pad a day, no progress on ED.  Trimix injection
No pads, 1/1/10,  9 month PSA < .01
1 year psa (364 days) .01


JB71
Regular Member


Date Joined Nov 2009
Total Posts : 206
   Posted 4/24/2010 12:33 PM (GMT -6)   
I better get off this Lupron CRAP soon then because it sure has made my belly rounder. More like 10 lbs.
of pure blubber.
Age, only 71.
July 2009, PSA 9.1, free ratio 0.16
September GLEASON 4+4=8, T2A
Prostate 44cc.
Calcium: 2.46  (range: 2.20 - 2.65 mmol/L)
25 Hydroxy Vitamin D: 102 (range: sufficiency:
76 - 250 nmol/L)
Bone Scan: Negative
CT Scan scheduled for Dec. 1st. Negative.
Started Casodex 50mg. on Nov. 6, first pill of 30.
Got Lupron 22.5mg ( 90 day ) on  November 19.
No real side effects as of Dec. 15 except dry skin and hair but getting quite 'porky' in the belt area even though now I go to the gym, three times a week. Also I dont have a need to shave anymore so now I can save my 'shaving' allowance and direct it to my stash of Depends !
 
Christmas Day got my first hot flashes. Thanks Santa!
 
Open surgery done on Jan. 20th. by Dr. J. Chin at London's University Hospital.
 
Cath removel scheduled for Feb. 8th. Yes, I know,
that will be 19 days. Dr. is out of country until then.
====================================
Pathology Report:
 
Gleason Score: cannot be determined due to hormone therapy effects. ???????
Extraprostatic Extension:
present, left radial, multifocal
present, left basal, multifocal
Resection Margins:
Apical: involved by invasive carcinoma, multifocal
Bladder Neck: involved by invasive carcinoma, unifocal on left side.Other: non-tumoural prostatic present at resection margin.
Perineural Invasion: present.
Seminal Vesicle Invasion: absent
Lymphovascular Invasion: absent
Lymph Node Status: no malignancy in regional lymph nodes
Additional path. findings:
high grade prostatic intraepithelial neoplasia
 
Pathology Stage: yp T3a NO MX
==================================
Radialogist appointment was on Friday Feb. 26 with Dr. Glenn Bauman in London.
Got another Lupron 90 day shot today and he wants to start IMRT soon. CT Scan plus measure scheduled in about 3 weeks. ( march 15)
 
First PSA test since surgery on March 18th.
with the results of <0.03 !!!
 
Started a Facebook page for bikers with prostate issues at:
 
IMRT to start on May 10.
 
.

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