Increase in PSA but still in zero club

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Colin45
Regular Member


Date Joined Feb 2009
Total Posts : 216
   Posted 4/23/2010 9:22 PM (GMT -6)   
I had my second 6 month psa check done and it has increased to .08 from .06 I am a bit disappointed at the result but the doctor said that it was not a problem
 
 
Age 64 From UK now in Thailand Baby boy born 2/14/2009
First PSA was showing 9.73 on 1/21/09.   on 5/7/09 PSA 9.78  Free PSA 0.83   Free:Total  PSA 0.08 
1/28/09 Biopsy carried out 12 core results show no adenocarcinoma
5/15/09 24 Core biopsy results Gleason'S Grade 3+2=5
Involving approx 30% of one out of 12 cores on each side no perineural or angiolymphatic invation identified
One side PIN High Grade Bone scan clear 
Open surgery 7/27/09
Prostate Gland weighting 34 grms lost one nerve bundle
Gleason upgraded to 3+3 Tumour not close to prostatic capsule Seminal Vesicles not involved by Tumour 6 Lymph Nodes negative for Malignant cells
First PSA Nov 2009 was 0.06 Continence 99% occasional stress dribbles no ED from first day after catheter removed


Tim-from-Maine
Regular Member


Date Joined Apr 2010
Total Posts : 83
   Posted 4/23/2010 9:33 PM (GMT -6)   
Hey, It's still under .1 - Could be test equipment calibration.
Dx age 62 - March 2009 - Gleason 7
Surgery - da-vinci RP on April 29, 2009 Gleason upgraded to 9
Started VEGAN diet June 2009
3 month PSA - <.04
6 month PSA <.04
9 month PSA .05
12 Month PSA  .16
 
 


BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 4/23/2010 10:12 PM (GMT -6)   
Colin, with a gleason 6, capsule contained, and a PSA below .1. I'd say that your doctor is correct. You shouldn't worry. Bb
Dx with PC Dec 2008 at 56, PSA 3.4, Biopsy: T1c, Geason 7 (3+4)

Robotic Surgery March 2009 Hartford Hospital, Dr Wagner
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes negitive
nerves spared, no negitive side effects of surgery

One night in hospital, back to work in 3 weeks

psa Junl 09 <.01
psa Oct 09 <.01
psa Jan 10 .07 re-test one week later .05
psa Mar 10 .28 re-test two weeks later .31


Sleepless09
Veteran Member


Date Joined Jul 2009
Total Posts : 1267
   Posted 4/23/2010 11:01 PM (GMT -6)   
Hey, Colin, great to hear from you.

With all that's been going on in Thailand, I've been wondering about you. Thanks for letting us know how you're doing.

If I went up 0.02 I'd be fussed too. I admit it. I start to worry if my neighbor's PSA goes us --- is it catching? But, it's not me and from my outside view I'd agree with your doctor. Please, do keep us posted.

Sheldon AKA Sleepless
Age 67 in Apil '09 at news of 4 of 12 cores positive T2B and Gleason 3 + 3 and 5% to 25% PSA 1.5
Re-read of slides in June said Gleason 3 + 4 same four cores 5% to 15%
June 29 daVinci prostatectomy, Dr. Eric Estey, at Royal Alexandra Hospital Edmonton one night stay
From "knock out" to wake up in recovery less than two hours.  Actual surgery 70 minutes
Flew home to Winnipeg on July 3 after 5 nights in Ramada Inn  ---  perfect recovery spot!
Catheter out July 9
Final pathology is 3 + 4 Gleason 7, clear margins, clear nodes, T2C, sugeron says report is "excellent"
 
Oct 1st 09 -- dry at night, during day some stress issues.
Oct 31st padless 24/7 
 
First post op PSA Sept 09  less than 0.02
PSA on Oct 23 test again less than 0.02
PSA on Jan 8 less than 0.02
PSA on April 9 less than 0.02 
 
  


Magaboo
Veteran Member


Date Joined Oct 2006
Total Posts : 1211
   Posted 4/23/2010 11:27 PM (GMT -6)   
Hi Colin,
 
My numbers were not as good as yours, so I kept a close eye on my post open RP PSA. After about 15 month it started to creep up. After 3 successive increases, when the PSA level reached .08, I got ready for SRT. By the time I started SRT the PSA had reached .1. If I were you, I would keep a closed eye on my PSA and start SRT as soon as I was convinced that it is a recurrence. It is my understanding that the chance of a positive outcome is best when SRT is started very early.
All the best to you.
 
Magaboo

Born Sept 1936
PSA 7.9
-ve DRE
Gleason's Score 3+4=7, 2 of 8 positive
Open RP 28 Nov 06 (nerve sparing), Post op staging T3a
Gleasons still 3+4=7
Seminal vesicles and lymph nodes clear
Catheter out 15 Dec 06, Dry since 11 Feb 07
All PSA tests in 2007 (4) <.04
PSA tests in 2008: Mar.=.04; Jun.=.05; Sept.=.08; 3 days before Rad Start=0.1
Salvage RT completed (33 sessions - 66 Grays) on the 19th Dec., 08.
PSA in Jan., 09=0.05; July 09=<0.04; JAN 10=<0.04


goodlife
Veteran Member


Date Joined May 2009
Total Posts : 2692
   Posted 4/24/2010 12:14 PM (GMT -6)   
As we all know, the "zero" club is really kind of a myth. What is really is, is the "What, me worry " Club. Our bodies have some natuarlly recurring PSA, as well as the surgeon may have left a small piece of protate laying around.

Until the numbers get to the point where we can tell it is not just some natural PSA, or some remnant of prostate causing it, let's enjoy our time in the What me worry Club, or the WMW Club for short.

Glad to hear you are doing well !
Goodlife
 
Age 58, PSA 4.47 Biopsy - 2/12 cores , Gleason 4 + 5 = 9
Da Vinci, Cleveland Clinic  4/14/09   Nerves spared, but carved up a little.
0/23 lymph nodes involved  pT3a NO MX
Catheter and 2 stints in ureters for 2 weeks .
Neg Margins, bladder neck negative
Living the Good Life, cancer free  6 week PSA  <.03
3 month PSA <.01 (different lab)
5 month PSA <.03 (undetectable)
6 Month PSA <.01
1 pad a day, no progress on ED.  Trimix injection
No pads, 1/1/10,  9 month PSA < .01
1 year psa (364 days) .01


JB71
Regular Member


Date Joined Nov 2009
Total Posts : 206
   Posted 4/24/2010 12:26 PM (GMT -6)   
Sawasdee Colin: Now is the time to start looking into a radiation treatment. Oncologist, uro, hospital facilities, etc. You wouldn't want to be traveling to Bangkok every day for that.

Just learned that my all time favourite Rock & Roll bar,
the Tahitian Queen on Beach Rd. had a fire. The place was allways "HOT" but the boys could have done without that. (Dirt Road mean anything to you?)


Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3741
   Posted 4/24/2010 12:40 PM (GMT -6)   
Colin,
Good (and bad) to hear from you. I saw what was going on in Bangkok and wondered if there were riots in the streets of Pattaya too. I'm pretty sure the rioting groups would not be the pro vs anti gov't, however. More likely it would be the "heteros" vs the "alternate life styles". The ratio was about 50-50 last time I was in the neighborhood.

I understand your concern. Two points do not a trend make. On the other hand every trend begins with two points. I will get my 9 month PSA results on Tuesday and am sweating already.

Let's hope that 0.02 was due to equipment noise or the result of Pattaya passion.
Cheers,
Jeff

Colin45
Regular Member


Date Joined Feb 2009
Total Posts : 216
   Posted 4/24/2010 7:42 PM (GMT -6)   
Hi Jeff  Most of the problems are in Bangkok although I hear that there was a demo. in Pattaya on Friday but it went on peacefully I do not live in Pattaya any more I have built and moved into a house in a place called Prachinburi it is about two and half hours away from both Pattaya and Bangkok although we still go to Pattaya once or twice a month I have restricted Internet access were I am now so although I look in here every day I do post very often
 
As I said in a reply to one of your messages I am not to sure how I am going to handle my PSA test any more I am not sure whether I will have any more take and just let what happens happen I do not think that I could handle  treatment  Radiation with a 5 hour return trip every day and by the time that I would be sure that it was a reoccurance I would be 66 years old and sometimes quality of life needs to be taken into account still that is looking into the future I know that I had an increase of 0.02 but it was over a 6 month period and talking to my doctor he would not look at doing anything until I reached 0.6 which I know is very high but they view things differently here in Thailand anyhow I am feeling a bit down at the moment things may look a bit different in a few weeks and I might have so different ideas by then
 
I hope and expect better news from you on Tuesday all the best of luck for you and I hope that you did not mind me venting my feelings on you Colin


 
 
Age 64 From UK now in Thailand Baby boy born 2/14/2009
First PSA was showing 9.73 on 1/21/09.   on 5/7/09 PSA 9.78  Free PSA 0.83   Free:Total  PSA 0.08 
1/28/09 Biopsy carried out 12 core results show no adenocarcinoma
5/15/09 24 Core biopsy results Gleason'S Grade 3+2=5
Involving approx 30% of one out of 12 cores on each side no perineural or angiolymphatic invation identified
One side PIN High Grade Bone scan clear 
Open surgery 7/27/09
Prostate Gland weighting 34 grms lost one nerve bundle
Gleason upgraded to 3+3 Tumour not close to prostatic capsule Seminal Vesicles not involved by Tumour 6 Lymph Nodes negative for Malignant cells
First PSA Nov 2009 was 0.06 April 2010 0.08 
Continence 99% occasional stress dribbles no ED from first day after catheter removed

Post Edited (Colin45) : 4/24/2010 6:59:07 PM (GMT-6)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 4/24/2010 9:51 PM (GMT -6)   
Colin,

Close only counts with hand grenades and horseshoes, so you are still in the zero club. Lots of legit reasons for flucactiosn in ultra sensitive testing. Hopefully, next time, it will either be the same or back down again. Good to hear from you.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one:  July
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 4/23 put in


Colin45
Regular Member


Date Joined Feb 2009
Total Posts : 216
   Posted 4/24/2010 11:01 PM (GMT -6)   
Thanks David I have been following your problems from afar and have noticed that you are back in the zero club good for you and hopefully all your problems will be worth it
 
 
Age 64 From UK now in Thailand Baby boy born 2/14/2009
First PSA was showing 9.73 on 1/21/09.   on 5/7/09 PSA 9.78  Free PSA 0.83   Free:Total  PSA 0.08 
1/28/09 Biopsy carried out 12 core results show no adenocarcinoma
5/15/09 24 Core biopsy results Gleason'S Grade 3+2=5
Involving approx 30% of one out of 12 cores on each side no perineural or angiolymphatic invation identified
One side PIN High Grade Bone scan clear 
Open surgery 7/27/09
Prostate Gland weighting 34 grms lost one nerve bundle
Gleason upgraded to 3+3 Tumour not close to prostatic capsule Seminal Vesicles not involved by Tumour 6 Lymph Nodes negative for Malignant cells
First PSA Nov 2009 was 0.06 April 2010 0.08 
Continence 99% occasional stress dribbles no ED from first day after catheter removed


BillyMac
Veteran Member


Date Joined Feb 2008
Total Posts : 1858
   Posted 4/24/2010 11:26 PM (GMT -6)   
Colin I remember your original diagnosis of 3+2=5 with only one core of 12 involved. Your post op pathology although upgraded slightly was also pretty good. I would not mind betting that seeing there was a very low PSA reading immediately post surgery that this is due to the nerve saving on one side (benign prostate tissue still attached). Given that, the very minor fluctuation of your two readings is not a cause for concern. I would continue to monitor it at the ultrasensitive level over the next year and watch what happens.
Bill
1/05 PSA----2.9 3/06-----3.2 3/07-------4.1 5/07------3.9 All negative DREs
Aged 59 when diagnosed
Biopsy 6/07
4 of 10 cores positive for Adenocarcinoma-------bummer!
Core 1 <5%, core 2----50%, core 3----60%, core 4----50%
Biopsy Pathologist's comment:
Gleason 4+3=7 (80% grade 4) Stage T2c
Neither extracapsular nor perineural invasion is identified
CT scan and Bone scan show no evidence of metastases
Da Vinci RP Aug 10th 2007
Post-op pathology:
Positive for perineural invasion and 1 small focal extension
Negative at surgical margins, negative node and negative vesicle involvement
Some 4+4=8 identified ........upgraded to Gleason 8
PSA Oct 07 <0.1 undetectable
PSA Jan 08 <0.1 undetectable
PSA April 08 <0.001 undetectable (disregarded due to lab "misreporting")
PSA August 08 <0.001 undetectable (disregarded due to lab "misreporting")
Post-op pathology rechecked by new lab:
Gleason downgraded to 4+3=7
Focal extension comprised of grade 3 cells
PSA September 08 <0.01 (new lab)
PSA February 09 <0.01
PSA August 09 (2 year mark), <0.01
PSA December 09 <0.01
        My Journey: http://www.yananow.net/Mentors/BillM2.htm
Never underestimate old people ............ you don't get to be old by being stupid.

Post Edited (BillyMac) : 4/25/2010 4:05:08 PM (GMT-6)


Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3741
   Posted 4/25/2010 1:49 PM (GMT -6)   
Good morning Colin,
I'm not sure if you check the email address you have listed here regularly. I sent you an email today with a couple of thoughts.
After a good night's sleep the world usually seems a little brighter.
Jeff
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