Does PSA Screening Save Lives? - Ask Dr. Myers

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MichGuy
Regular Member


Date Joined Jan 2009
Total Posts : 51
   Posted 4/29/2010 2:57 PM (GMT -6)   
Hi everyone,
 
This video directly addresses the issues surronding the so-called PSA testing "controversy".  I think everyone here would benefit from listening to what Dr. Myers has to say.  Plus, the website, has numerous other videos of Dr. Myers discussing various aspects of PC, particularly diet issues.  Here is the link:
 
 
MichGuy

Age: 60, 59 at DX
PSA: 1/20/00 7.9, 7/22/00 3.3, 10/25/01 4.9, 10/19/04 5.1, 9/26/07 5.98, 8/28/08 7.68, 9/23/08 7.36, 10/23/08 8.64, 12/18/08 6.39
Prostate size: 96 gm (est.), post-surgical: 112 gm
Biopsy: 11/7/08 Positive 2 of 15 cores, both in rt apex, composite tumor quantity 5% prostate involved, Gleason 7 (3+4), Gleason pattern 4 accounts for 15% of tumor
Stage: T1c
DaVinci robotic surgery: 3/9/09, Dr. M. Hugh Solomon at St. Joseph Mercy Hospital, Ann Arbor, MI
Nerves: Spared left nerve bundle and partial sparing of right nerve bundle
Cath removed: 3/19/09
Pathology results: Gleason: 3+3=6, Tumor Quality: 3% of prostatic tissue; max. linear extent 4 mm, location: bilateral (apices), no extracapsular extension, no seminal vesicle invasion, no perineural invasion and no angiolymphatic invasion. Margins: Focal involvement (1mm) of left apical margin
Pathologic stage: pT2c N0 Mx
Left inguinal hernia 3 months post-surgery (repaired via open surgery), also had right inguinal hernia 2 years pre-surgery (repaired laparoscopically) 
PSA's post surgical:  2  mo.= .06, 4 mo.=.02, 7 mo.=.02, 10 mo.=.01


Magaboo
Veteran Member


Date Joined Oct 2006
Total Posts : 1211
   Posted 4/29/2010 4:11 PM (GMT -6)   
Hi MichGuy,
 
Thanks so much for the URL to this interesting and informative series of videos. Very worthwhile to listen to for many of us. I was particularly intrigued and surprised to learn that consumption of sugar does NOT encourage the growth of cancer. I had always believed  that cancer feeds on sugar! I guess I was totally wrong! 
Very interesting stuff from Dr. Myers.
Hope you're doing well. All the best to you.
 
Magaboo

Born Sept 1936
PSA 7.9
-ve DRE
Gleason's Score 3+4=7, 2 of 8 positive
Open RP 28 Nov 06 (nerve sparing), Post op staging T3a
Gleasons still 3+4=7
Seminal vesicles and lymph nodes clear
Catheter out 15 Dec 06, Dry since 11 Feb 07
All PSA tests in 2007 (4) <.04
PSA tests in 2008: Mar.=.04; Jun.=.05; Sept.=.08; 3 days before Rad Start=0.1
Salvage RT completed (33 sessions - 66 Grays) on the 19th Dec., 08.
PSA in Jan., 09=0.05; July 09=<0.04; JAN 10=<0.04


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4268
   Posted 4/29/2010 4:37 PM (GMT -6)   
Good thoughtful response to the subject of screening.
JT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


MichGuy
Regular Member


Date Joined Jan 2009
Total Posts : 51
   Posted 4/29/2010 6:18 PM (GMT -6)   
Magaboo,
 
Thank you for the good wishes.  I hope all stays well with you too.
 
MichGuy
Age: 60, 59 at DX
PSA: 1/20/00 7.9, 7/22/00 3.3, 10/25/01 4.9, 10/19/04 5.1, 9/26/07 5.98, 8/28/08 7.68, 9/23/08 7.36, 10/23/08 8.64, 12/18/08 6.39
Prostate size: 96 gm (est.), post-surgical: 112 gm
Biopsy: 11/7/08 Positive 2 of 15 cores, both in rt apex, composite tumor quantity 5% prostate involved, Gleason 7 (3+4), Gleason pattern 4 accounts for 15% of tumor
Stage: T1c
DaVinci robotic surgery: 3/9/09, Dr. M. Hugh Solomon at St. Joseph Mercy Hospital, Ann Arbor, MI
Nerves: Spared left nerve bundle and partial sparing of right nerve bundle
Cath removed: 3/19/09
Pathology results: Gleason: 3+3=6, Tumor Quality: 3% of prostatic tissue; max. linear extent 4 mm, location: bilateral (apices), no extracapsular extension, no seminal vesicle invasion, no perineural invasion and no angiolymphatic invasion. Margins: Focal involvement (1mm) of left apical margin
Pathologic stage: pT2c N0 Mx
Left inguinal hernia 3 months post-surgery (repaired via open surgery), also had right inguinal hernia 2 years pre-surgery (repaired laparoscopically) 
PSA's post surgical:  2  mo.= .06, 4 mo.=.02, 7 mo.=.02, 10 mo.=.01


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 4/29/2010 7:16 PM (GMT -6)   
Mag, glad to hear about the falsity of the sugar connection, or I would really be screwed. I don't smoke or drink a drop, but I am a well known chocolate freak and sugar junky.

Good link, Mich Guy
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one:  July
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 4/23 put in


mjluke
Regular Member


Date Joined Jan 2009
Total Posts : 189
   Posted 4/29/2010 8:51 PM (GMT -6)   
I am wary of any advice from a doctor who calls himself "snuffy".

 
63 years old-tumor discovered on digital exam- biopsy December 2008-
4 of 12 samples positive-all on right side
Gleason 3+3=6
PSA-3
Otherwise excellent health.
Brachytherapy- May 19, 2009 -so far, so good.
 
  "There may come a day when the courage of men will fail, but it will not be this day."


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 4/29/2010 8:56 PM (GMT -6)   
that was pretty good, mjluke, that made me laugh
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one:  July
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 4/23 put in


mjluke
Regular Member


Date Joined Jan 2009
Total Posts : 189
   Posted 4/29/2010 9:12 PM (GMT -6)   
Hey Purgatory:
 
I hope you are having a pain-free evening.
 
63 years old-tumor discovered on digital exam- biopsy December 2008-
4 of 12 samples positive-all on right side
Gleason 3+3=6
PSA-3
Otherwise excellent health.
Brachytherapy- May 19, 2009 -so far, so good.
 
  "There may come a day when the courage of men will fail, but it will not be this day."


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 4/29/2010 9:15 PM (GMT -6)   
Still a big improvement from even a week ago. I will take what I can get at this point.
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one:  July
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 4/23 put in


MichGuy
Regular Member


Date Joined Jan 2009
Total Posts : 51
   Posted 4/30/2010 10:41 AM (GMT -6)   
mjluke said:  I am wary of any advice from a doctor who calls himself "snuffy".
 
I agree...unusual nickname.  While I have no connection to him, nor have I ever met him, I did find this short bio on his website:
 
Who is Dr. Snuffy Myers?
 
Medical oncologist and prostate cancer survivor, Dr. Charles "Snuffy" Myers was a key player in creating AZT, Suramin, and Phenylacetate while working at the National Institute of Health. With over 250 research papers published, Myers is one of the leading developers of today's prostate cancer canon on both the research and treatment side of the test tube.
 
Here's more (plus, it's a pretty interesting PCa website):  http://www.prostateforum.com/about-dr-myers.html
 
MichGuy
 

Age: 60, 59 at DX
PSA: 1/20/00 7.9, 7/22/00 3.3, 10/25/01 4.9, 10/19/04 5.1, 9/26/07 5.98, 8/28/08 7.68, 9/23/08 7.36, 10/23/08 8.64, 12/18/08 6.39
Prostate size: 96 gm (est.), post-surgical: 112 gm
Biopsy: 11/7/08 Positive 2 of 15 cores, both in rt apex, composite tumor quantity 5% prostate involved, Gleason 7 (3+4), Gleason pattern 4 accounts for 15% of tumor
Stage: T1c
DaVinci robotic surgery: 3/9/09, Dr. M. Hugh Solomon at St. Joseph Mercy Hospital, Ann Arbor, MI
Nerves: Spared left nerve bundle and partial sparing of right nerve bundle
Cath removed: 3/19/09
Pathology results: Gleason: 3+3=6, Tumor Quality: 3% of prostatic tissue; max. linear extent 4 mm, location: bilateral (apices), no extracapsular extension, no seminal vesicle invasion, no perineural invasion and no angiolymphatic invasion. Margins: Focal involvement (1mm) of left apical margin
Pathologic stage: pT2c N0 Mx
Left inguinal hernia 3 months post-surgery (repaired via open surgery), also had right inguinal hernia 2 years pre-surgery (repaired laparoscopically) 
PSA's post surgical:  2  mo.= .06, 4 mo.=.02, 7 mo.=.02, 10 mo.=.01

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