psa 17 following prostate removal 2006 and radiation 2007

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tenniguy
New Member


Date Joined May 2010
Total Posts : 2
   Posted 5/12/2010 4:10 PM (GMT -6)   
psa went from fractional to 3 and then from 6 to 6 in the two years following radiation. I thought the Pomagranate pills my daughter found on the net were holding it but now it spiked to 17 and my Doc. says start Lupron. What do you folks think?  I'm 71 and feel good as far as energy is concerned.

BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 5/12/2010 5:07 PM (GMT -6)   
A PSA of 17 is pretty high, and if you are 71 and still in good health you have a lot of years left. I would go with the HT. Who knows, maybe side effects will be tolerable for you. You can always stop. Good luck. BB
Dx with PC Dec 2008 at 56, PSA 3.4, Biopsy: T1c, Geason 7 (3+4)

Robotic Surgery March 2009 Hartford Hospital, Dr Wagner
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes negitive
nerves spared, no negitive side effects of surgery

One night in hospital, back to work in 3 weeks

psa Junl 09 <.01
psa Oct 09 <.01
psa Jan 10 .07 re-test one week later .05
psa Mar 10 .28 re-test two weeks later .31
Aril 10 MRI and Bone Scan show lesion on lower spine, no SRT


tenniguy
New Member


Date Joined May 2010
Total Posts : 2
   Posted 5/12/2010 5:44 PM (GMT -6)   
thanks, I really appreciate the feed back. jim may

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4268
   Posted 5/12/2010 6:37 PM (GMT -6)   
It's pretty obvious that your PC has gone matastic. You should start triple hormone blockade immediately from an oncologist specializing in prostate cancer.
JT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


mgl
Regular Member


Date Joined Feb 2007
Total Posts : 122
   Posted 5/13/2010 6:24 AM (GMT -6)   
I would talk to an oncologist ,The best to you

50 years old
gleason 3+4=7 psa5.8 clinical stageT3a
Da vinci surgery April10 2007 Mayo clinic Rochester, Mn.
extraprostatic extension Gleason -same
pelvic lymph nodes -negative
Catheter out April 19
psa aug 2007 0.28
37 treatments IMRT ended 10/26/07
psa Jan 29 2008 0.10
psa april 30 0.14
psa aug 21, 0.16
psa dec 17 o8 , 0.16
psa apr 09, 0.21
psa aug 09, 0.26
psa feb 10, 0.51
mri and biopsy ,mayo clinic  march 2010


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 5/13/2010 7:29 AM (GMT -6)   
You have alot of possible choices to try other than Lupron and side effects are much less or different:
ketoconazole
DES (man made estrogen-works on hrpca better than Lupron would)
Emcyt
Estradiol patches (similar effects of DES, much less side effects)

Other wise ADT3 triple hormone blockage may be worth trying out, as John T mentioned

There are even other drugs to consider, a PCa specialist onco-doc should know this realm, you are beyond any uro docs expertise.

Best to you
Youth is wasted on the Young-(W.C. Fields)

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