salvage cryotherapy

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aerolite21
New Member


Date Joined May 2010
Total Posts : 3
   Posted 5/14/2010 11:31 AM (GMT -6)   
I am 75 years old and was treated for prostate cancer in 2004, PSA 5.2, Gleason 7, with seed implants and IMRT. My PSA was never below 1.6 and is now rising to 3.8. Otherwise in good health and no symptoms. A urologist is recommending cryotherapy if there is no evidence of metastisis which is being determined. Has anyone had experience with cryotherapy in this kind of situation? The other option would be hormone therapy which would likely become refractory in a few years.

Post Edited (aerolite21) : 5/15/2010 11:13:08 AM (GMT-6)


medved
Veteran Member


Date Joined Nov 2009
Total Posts : 1096
   Posted 5/14/2010 11:48 AM (GMT -6)   
A key issue in this situation is how you are testing to evaluate whether the cancer is systemic.  CT scans and the like typically don't do the trick because they cannot pick up all systemic (or even most systemic) disease.  There are other tools, but most of them are predictive (that is, they can tell you the likelihood that your disease is sytemic, but cannot tell you for certain that your disease is not systemic).   Most doctors would tell you that if your disease is systemic, cryo is useless. 
 
My advice is try to get the best handle you can -- by talking with true experts in the field -- about the likelihood that your cancer is systemic, before diving into the cryo.  
 
My father had a salvage cryo procedure after failed EBRT.  But his cancer had already spread, so he went through the annoyance of the procedure for nothing.  (Actually, in his case it was more than annoyance -- he developed pulmonary emboli as a post-procedure complication -- but I don't think that is so common, particularly if you follow the advice to walk around, etc., during recovery). 
 
If you have the cryo, continue to monitor your psa carefully.  It may turn out you need hormone treatments anyway.   The good news is many patients live a long time on hormone treatment.
 
Best wishes,
 
Age 46.  Father died of p ca. 
My psa starting age 40: 1.4, 1.3, 1.43, 1.74, 1.7, 1.5, 1.5
 


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 5/14/2010 11:59 AM (GMT -6)   
aerolite, welcome to our corner of the world, and to HW Prostate Cancer. Glad you found us, sorry you need to be here.

Not pretending to be your doctor, but at your age, the stats you gave, and your general health, the right mix of HT might be the next best thing for you. I personally don't have a lot of faith in the cyro method, though plenty of men have used it with great success. As medved posted above, it would be a shame to go through cyro as a salvage method, only to have to need HT anyhow.

Please keep us posted.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one:  July
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 4/23 put in

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