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Gregz263
Regular Member


Date Joined May 2010
Total Posts : 140
   Posted 5/14/2010 2:30 PM (GMT -6)   

Let me start by giving you a little background.

I am 44 years old. White with no history of PCa in my family. At the age of 40 in 2006 I had my first PSA done which came back at 1.0. There was no concern as I was well below the "normal" range. In April 2009 my PSA was checked again during my routine physical. This time the result was 2.9. Again my PHP was not concerned. In April this year another routine test was done, resulting in a reading of 4.6. A repeat test came back 4.4. (different lab) I am otherwise in excellent health.

My PHP referred me to a Urologist.  I was examined by my Urologist who informed me that my DRE was normal. The Prostate was not enlarged and he felt nothing abnormal. I also have no symptoms of any kind. Urologist ordered a FPSA test. Those results were 4.7 and 6%. I have done enough research on my own to know those numbers are not good. On Tuesday 5/11 I had a TRUS biopsy. Nothing abnormal was observed. The only thing notable was some calcification in the gland.

 Now as I wait for the biopsy results my mind begins to wander. Urologist stated that if it is in fact PCa it would be in very early stages, which helps put my mind at ease. However I am a bit concerned with the velocity although I have not discussed this with my urologist.

 I have mixed emotions on the potential results. While I do not wish for a positive biopsy I think it would be easier than repeat Biopsy and testing. Any suggestions or words of encouragement out there?


60Michael
Veteran Member


Date Joined Jan 2009
Total Posts : 2229
   Posted 5/14/2010 2:47 PM (GMT -6)   
Welcome Greg,
Obviously something is going on and lets hope it is minor and if indeed it is Pca, perhaps it has been caught early. It's difficult to keep the mind from racing until you know the results however. Keep us posted and lets hope for the best.
Michael
Dx with PCA 12/08 2 out of 12 cores positive 4.5 psa
59 yo when diagnosed, 61 yo 2010
Robotic surgery 5/09 Atlanta, Ga
Catheter out after 10 days
Gleason upgraded to 3+5, volume less than 10%
2 pads per day, 1 depends but getting better,
 started ED tx 7/17, slow go
Post op dx of neuropathy
T2C left lateral and left posterior margins involved
3 months psa.01, 6 month psa.4, 6 1/2 month psa.5 on 11/28/10
Starting IMRT on 1/18/10, Completed 39 tx at 70 gys on 3/12/10
6 week Post IMRT PSA .44 a drop from .5 but maybe more
Great family and friends
Michael


compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7211
   Posted 5/14/2010 4:01 PM (GMT -6)   

We have all been there.

When are you expecting the biopsy results?

Mel


63 years old . PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (Free PSA 24%),  after 45 days on cipro! DREs have always been normal. PCA-3 was about 75 (way above the 35 threshold). That led to:

Biopsy on 11/30/09. 5 out of 12 cores positive. Gleason 4+3. 2 cores were 3+3 (one 5% and the other 30%) on one side. On  other side:2 cores are 4+3 (5%)--1 core 3+4 (30%) no peri-neural invasion. prostate is 45 grams. Stage: T1C.  

Surgery with Dr. Menon at Ford Hospital, 1/26/10. He says all looked good. Spared nerves. Unfortunately: Pathology Report: G 4+3 (65%-35%). Cancer in 15% of gland. Lymph Nodes: Clear.  Perineural Invasion: yes. Seminal Vessical Involvement: No.  Extraprostatic Extension: yes.  Positive Margin: Yes-- focal-- 1 spot .5mm. Final Weight is 52.7 gms.  (Second opinion from Jon Epstein at Hopkins confirmed these results)

 Incontinence: joined that club-- definite leaks—1 pad/day. Night is dry, was  using 1 pad at night for security, but pretty much dispensed with that most nights. Update: no pads at night. No pads while at home, but still very uncomfortable. Use 1 pad for out-of-house activities. Suddenly got MUCH better on 3/10/10, almost overnight. Still some urgency but no pads about 90% of the time.  As of 3/12/10--completely continent! Uh...OH. As of about 3/16/10 problems with constant urgency although no pads needed--feels like an infection but none showing in urine.

Update: since late March all is well in that area. I would say 99.9% continent (a spurt here and there, maybe 5 spurts per week).

First post-op PSA on 3/10/10--DRUM ROLL: 0.01 Next PSA in mid-June.


Paul1959
Veteran Member


Date Joined Nov 2007
Total Posts : 598
   Posted 5/14/2010 4:01 PM (GMT -6)   
Greg,
Welcome, sorry you have to be here. I was 45 when my numbers started rising...and finally diagnosed a couple years later.
Sounds as if it has been caught early. Yes, there is always the chance that it's nothing, but your research is right - I did the same research. As a younger guy, the good news is that recovery from the surgery is usually really good and your side effects are usually less.
Email me if you'd like to talk.
Paul
www.franktalk.org ED website for PCa guys

46 at Diagnosis.
Father died of Pca 4/07 at 86.
10/07 PSA 5.06 (Biopsy 11/07 1 of 12 with 8% involvment) (1mm)
Da Vinci surgery Jan 5, '08 at Mt. Sinai Hosp. NYC www.roboticoncology.com
Saved both nerve bundles.
Path Report: Stage T2cNxMx
-Gleason (3+3)6
Pad free on March 14 - (10 weeks.) Never a problem since.
ED - at one year, ED is fine with viagra.
Two year PSA - undetectable!


CaPCa
Regular Member


Date Joined Aug 2007
Total Posts : 118
   Posted 5/14/2010 5:01 PM (GMT -6)   
Greg,

Good luck with the biopsy results. If I had to live my journey over again, I would try to do a better job not worrying about things that have not, or never will, take place. Even though my outcome was as successful as could possibly be (so far), I cannot get back those many hours of worry and anxiety that cancer took from me. As others have said, you can take comfort in the likelihood that you caught it early IF the test does come back positive.

CaPCa
Age:45 (44 when diagnosed)
Father diagnosed and cured at age 52.
08/21/07: Diagnosed with T1c cancer
1 of 12 biopsy cores positive; 10% tissue
Gleason score: 3+3=6
PSA level prior to biopsy: 4.3 (velocity < 0.4ng/ml)
10/19/07: da Vinci prostatectomy by Dr. Vipul Patel
              Difficult surgery due to prostate inflammation.
              Both nerve bundles spared.
              Spongy erections began within 24hrs of surgery!
10/24/07: Catheter out; down to 1 Serenity pad/day next day.
              Final pathology: neg margins, no capsular penetration,
              Gleason 3+3=6, 5% tumor involvement, multi-focal.
11/04/07  First usable erection with Cialis
11/22/07  Thanksgiving - Bye-bye, pads
01/17/08  First post-surgery PSA result: < 0.008 ng/ml
03/17/08  Erection quality mostly back to pre-surgery levels with Cialis;
              have not tried without meds yet.
04/23/08  Second post-surgery PSA result: < 0.008 ng/ml
07/30/08  Third PSA: 0.01 ng/ml
11/04/08  One year PSA: 0.01
              Still taking 10mg Cialis every other day - enjoying the results
              too much to stop yet.
02/07/09  Taking 5mg Cialis every other day - having too much fun to try
              to stop for now.
03/23/09  PSA: 0.02
10/19/09 PSA: < 0.1 (switched to "standard" assay)
 


Casey59
Veteran Member


Date Joined Sep 2009
Total Posts : 3172
   Posted 5/14/2010 5:19 PM (GMT -6)   
Hi Greg, and welcome.
 
Please be aware that an elevated PSA and a correspondingly low Free PSA percentage can be caused by a prostate infection (prostatitis), which is a benign rather than a malignant condition.  In other words, Free PSA alone had no diagnostic power in distinguishing prostate cancer (PC) from prostatitis.
 
The American Urological Association's PSA "Best Practices" document (2009 Update) advises doctors that consideration should be given to confirming an abnormal PSA before proceeding to biopsy.  The majority of biopsy proceedures do NOT find PC, and the AUA feels that doctors should do more "due diligence" to eliminate prostatitis, infection or non-cancerous BPH before moving to a biopsy.  Anyhow, sounds like your urologist jumped right to a biopsy (which is not uncommon)...or did he do a urine/culture test to determine infection (something you didn't mention)?
 
The more common (and AUA recommended) approach would have been to test for infection first...I would say especially with the fairly rapid rise you experienced in PSA, which is very unlike the typical PC but is like infection symptoms.  If prostatitis symptoms are noted, four to six weeks of Cipro or similar antibiotic should be prescribed prior to recommending a biopsy.  At the end of the Cipro therapy, a repeat PSA determination should be made. If there is significant lowering of the PSA, an element of prostatitis is likely to be present. Because it is also possible to have both prostatitis and PC, the PSA value after antibiotic therapy will more aptly reflect the status of the patient in the situation where a diagnosis of PCis subsequently established.
 
 
Hoping for good results for you.  If no PC is found, ask your doctor about eliminating non-cancerous causes of PSA elevation...like prostatitis.
 
best wishes...

Gregz263
Regular Member


Date Joined May 2010
Total Posts : 140
   Posted 5/14/2010 6:28 PM (GMT -6)   
Thanks Guys. I appreciate the support!
Casey59, I did ask for my urine specimen to be checked for infection, though the Uro had not requested it. I know the nurse would have followed through but I was never given any results. I have no symptoms of infection. Is it possible I could harbor an infection or prostatitis over several years without symptoms?

I expect my Biopsy results next week.

Paul1959- Dr. Samadi? Looking to go the same route if needed. Will send you PM.

Thanks again guys!

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 5/14/2010 7:29 PM (GMT -6)   
Greg, welcome here to our corner of the world.

You have already been given some pretty good advice.

Keep in mind, that there are many of us with PC, that never had a positive DRE, or any symptons of prostate problems, some with real low PSA numbers, etc.

As far as biopsies go, the waiting game is always rough. Some men get by with just one, others more. I had 3 within 18 months before a positive dx of PC. I believe we have one brother here who had 12 biopsies.

Good luck, I hope you don't need to join our brotherhood here, but if you end up with a PC dx, this is a great place to hang out, to gain knowledge, to have support, etc.

Please keep us posted.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one:  July
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 4/23 put in


Casey59
Veteran Member


Date Joined Sep 2009
Total Posts : 3172
   Posted 5/14/2010 9:07 PM (GMT -6)   
Gregz263 said...
...I have no symptoms of infection. Is it possible I could harbor an infection or prostatitis over several years without symptoms?...
Yes.  There are often no symptoms of infection.

Gregz263
Regular Member


Date Joined May 2010
Total Posts : 140
   Posted 5/15/2010 8:48 AM (GMT -6)   
If my Biopsy is to come back negative what test could/should I ask for next?

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7211
   Posted 5/15/2010 2:04 PM (GMT -6)   

Greg:

 

That's a good question. If the biopsy is negative, then wait and keep monitoring your PSA. If it goes up more, get a PCA-3 test.  That test should indicate if a repeat biopsy is needed.

Also, there is something called a saturation biopsy (more cores are taken). They can always do that, but probably only if you have a few negative biopsies and if they are suspicious that you have PC.

 

Mel


63 years old . PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (Free PSA 24%),  after 45 days on cipro! DREs have always been normal. PCA-3 was about 75 (way above the 35 threshold). That led to:

Biopsy on 11/30/09. 5 out of 12 cores positive. Gleason 4+3. 2 cores were 3+3 (one 5% and the other 30%) on one side. On  other side:2 cores are 4+3 (5%)--1 core 3+4 (30%) no peri-neural invasion. prostate is 45 grams. Stage: T1C.  

Surgery with Dr. Menon at Ford Hospital, 1/26/10. He says all looked good. Spared nerves. Unfortunately: Pathology Report: G 4+3 (65%-35%). Cancer in 15% of gland. Lymph Nodes: Clear.  Perineural Invasion: yes. Seminal Vessical Involvement: No.  Extraprostatic Extension: yes.  Positive Margin: Yes-- focal-- 1 spot .5mm. Final Weight is 52.7 gms.  (Second opinion from Jon Epstein at Hopkins confirmed these results)

 Incontinence: joined that club-- definite leaks—1 pad/day. Night is dry, was  using 1 pad at night for security, but pretty much dispensed with that most nights. Update: no pads at night. No pads while at home, but still very uncomfortable. Use 1 pad for out-of-house activities. Suddenly got MUCH better on 3/10/10, almost overnight. Still some urgency but no pads about 90% of the time.  As of 3/12/10--completely continent! Uh...OH. As of about 3/16/10 problems with constant urgency although no pads needed--feels like an infection but none showing in urine.

Update: since late March all is well in that area. I would say 99.9% continent (a spurt here and there, maybe 5 spurts per week).

First post-op PSA on 3/10/10--DRUM ROLL: 0.01 Next PSA in mid-June.


Gregz263
Regular Member


Date Joined May 2010
Total Posts : 140
   Posted 5/29/2010 5:14 AM (GMT -6)   
Got my biopsy results yesterday. 12 of 12 cores negative. However my Urologist is concerned that he cannot find any other reason for the elevated PSA and that my numbers and velocity are "worrisome".
Looking into color doppler ultrasound. Anyone have any idea where I can find a facility with this equipment in the New England area?

Gregz263
Regular Member


Date Joined May 2010
Total Posts : 140
   Posted 8/4/2010 12:41 PM (GMT -6)   
Got a second opinion and subsequently a second biopsy, again, all negative ***??? Infection, inflammation and BPH all ruled out. Dr says wait 6 months then repeat PSA and likely biopsy again. Anyone have any experience with color doppler guided biopsy or TARGET biopsy?
PSA 1/06 at age 40 = 1.0
PSA 4/09 at age 43 = 2.9
PSA 4/10 at age 44 = 4.6
 
FPSA 4/09 = 4.7 and 6%
Biopsy 5/11/10 12 out of 12 negative

medved
Veteran Member


Date Joined Nov 2009
Total Posts : 1096
   Posted 8/4/2010 1:53 PM (GMT -6)   
<<Looking into color doppler ultrasound. Anyone have any idea where I can find a facility with this equipment in the New England area?>>

You might call Duke Bahn in LA or Fred Lee in Rochester Michigan -- two well known experts -- and ask them for a recommendation in New England. Or, if you are in a position to travel, you could see one of them. Alternatively, you could call one of the docs at Brigham & Womens Hospital in Boston (eg, Dr. Hu) and ask them. You might ask about color doppler, an MRI-guided biopsy, or a saturation biopsy. Good luck.
Age 46.  Father died of p ca. 
My psa starting age 40: 1.4, 1.3, 1.43, 1.74, 1.7, 1.5, 1.5
 

cooper360
Regular Member


Date Joined Jul 2010
Total Posts : 161
   Posted 8/4/2010 4:08 PM (GMT -6)   
Yes definitely get a color doppler from Dr Lee or Dr Bauhn,my husband did[Dr Lee] and it saved him from even getting a biopsy!! Some will tell you that color doppler cannot rule out PCa but I'll will argue long and loud that it can!! [if done by one of the very few experts] My husband and I just got home this afternoon,from Dr Lee's office after quite a few stressful months after family Dr and uro Dr wanted to biopsy. Dr Lee after 2 visits  exam and color doppler,2 wks on Bactrim,wait 2 wks,retest psa diagnosed prostatitis and said see you next year! Family Dr & uro Dr both were sure PCa, after 4 psa's 5.5,5.9,7.1,5.5 Dr Lee after careful color scan,saw some inflammation which was cleared up w/bactrim and no areas to biopsy!

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4235
   Posted 8/4/2010 6:50 PM (GMT -6)   
Color doppler is available from Dr Sconti and Dr Bard in NYC. If have read some of Bard's papers and was not impressed. Have heard some good things of Dr Sconti. If I were on the east coast I would go to Sarosota Fla and the Dattoli Cancer Center for a CDU.
On the West coast you can't go wrong with Dr Duke Bahn or Dr Doug Chin in So Cal. But the master still is Dr Fred Lee in Rochester MI.
JT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


Fairwind
Veteran Member


Date Joined Jul 2010
Total Posts : 3781
   Posted 8/4/2010 7:05 PM (GMT -6)   
You can look at my history as see you are not alone..My PSA was 14 (adjusted for Proscar) before the third biopsy found it..My U-doc was pushing for that third biopsy sooner but I resisted it..

He said a standard 12 core biopsy will find 90% of all prostate cancers. The second biopsy will find 95% and the third 98%....

Maybe they just make this stuff up, Who knows??
Age today: 68. Married, 6', 215 pounds, active, no health issues.
PSA at age 55: 3.5, DRE negative. Advice, "Keep an eye on it".
PSA at age 58: 4.5
PSA at age 61: 5.2
PSA at age 64: 7.5, DRE "Abnormal"
PSA at age 65: 8.5, DRE " normal", biopsy, 12 core, negative...
PSA at age 66 9.0 DRE "normal", BPH, Finesteride. (Proscar)
PSA at age 67 4.5 DRE "normal" second biopsy, negative.
PSA at age 67.5 5.6, DRE "normal" U-doc worried..
PSA at age 68, 7.0, third biopsy positive for cancer in 4 cores, 3 cores Gleason 6, one core Gleason 9. Finesteride discontinued, still no urinary symptoms, never had any..From age 55 to 65 I had no health insurance.

I have a date with the robo surgeon on Sept 3 but I'm keeping my options open. I'm also looking at seeds combined with IGRT which seems to be having good results with high-risk patients..

Gregz263
Regular Member


Date Joined May 2010
Total Posts : 140
   Posted 8/5/2010 6:07 PM (GMT -6)   
Just made an appointment for a color doppler guided saturation biopsy with Dattoli. Hope we can put this to bed!
PSA 1/06 at age 40 = 1.0
PSA 4/09 at age 43 = 2.9

PSA 4/10 at age 44 = 4.6



FPSA 4/09 = 4.7 and 6%

Biopsy 5/11/10 12 out of 12 negative

2nd Biopsy 7/13/10 12 out of 12 negative

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4235
   Posted 8/5/2010 6:58 PM (GMT -6)   
Greg,
Please give us a report on how it went.
Good luck
JT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


cooper360
Regular Member


Date Joined Jul 2010
Total Posts : 161
   Posted 8/6/2010 7:49 AM (GMT -6)   
Glad to here it!!!!! Good luck, hope all goes well.

Gregz263
Regular Member


Date Joined May 2010
Total Posts : 140
   Posted 10/5/2010 2:33 PM (GMT -6)   
Latest numbers are in PSA 4.7 FPSA 9%

Color doppler guided saturation biopsy at Dattoli scheduled for 11/03.

Looking for an answer
PSA 1/06 at age 40 = 1.0
PSA 4/09 at age 43 = 2.9

PSA 4/10 at age 44 = 4.6



FPSA 4/09 = 4.7 and 6%

Biopsy 5/11/10 12 out of 12 negative

2nd Biopsy 7/13/10 12 out of 12 negative

Highwayman
Regular Member


Date Joined Sep 2010
Total Posts : 148
   Posted 10/5/2010 4:23 PM (GMT -6)   
Good luck Greg!
Keep posting. I'm hoping for a good ending.
Mike
Age 48 w/diagnosed
10/25/06 PSA 3.0
11/13/06 PSA 3.8
11/13/06 PSA FREE 0.5
11/13/06 PSA % FREE 13.2
10/25/07 PSA 3.4
12/18/07 Biopsy-neg
6/2008 PSA 3.5
1/7/09 PSA 4.6
6/18/09 psa 5.8
2/9/10 psa 8.7
5/13/10 psa 10.5
7/19/10 PSA 10.8
8/19/2010 3rd Needle core biopsy- single focus of prostatic adenocarcinoma, Gleason Grade 3+3=6, Tumor involves one of eight cores -2%, Prostate 78 (big)

Fairwind
Veteran Member


Date Joined Jul 2010
Total Posts : 3781
   Posted 10/5/2010 6:41 PM (GMT -6)   
History Lessons..
Age 68.
PSA at age 55: 3.5, DRE normal. Advice, "Keep an eye on it".
age 58: 4.5
age 61: 5.2
age 64: 7.5, DRE "Abnormal"
age 65: 8.5, " normal", biopsy, 12 core, negative...
age 66 9.0 "normal", 2ed biopsy, negative, BPH, Proscar
age 67 4.5 DRE "normal"
age 68 7.0 third biopsy positive, 4 out of 12, G-6,7, 9
RRP performed Sept 3 2010, pos margin, one pos vesicle nodes neg

An38
Veteran Member


Date Joined Mar 2010
Total Posts : 1149
   Posted 10/6/2010 3:41 AM (GMT -6)   
Seems like a great choice Greg, I can't think of a better option in your situation. I hope you get the all clear but if there is a cancer there this is your best bet.

An
Husband's age: 52. Sydney Australia.
Family history: Mat. grandfather died of PC at 72. Mat. uncle died of PC at 60. He has hereditary PC.
PSA: Aug07 - 2.5|Feb08 - 1.7|Oct09 - 3.67 (free PSA 27%)|Feb10 - 4.03 (free PSA 31%) |Jun10 - 2.69. DRE normal.
Biopsy 28Apr10: negative for a diagnosis of PC however 3 focal ASAPs “atypical, suspicious but not diagnostic” for PC. Review of biopsy by experienced pathologist, 1/12 core: 10% 3+3 (left transitional), 1/12 core: ASAP (left apex)
Nerve sparing RP, 20Aug10 with Dr Stricker. Post-op path: 3+4 (ISUP 2005). Neg margins, seminal vesicles, extraprostatic extension. Multifocal, with involvement in the peripheral, apex, fibro-muscular and transitional zones.

Gregz263
Regular Member


Date Joined May 2010
Total Posts : 140
   Posted 10/6/2010 5:13 AM (GMT -6)   
I think I am doing all I can do. Thanks for the encouragement.
PSA 1/06 at age 40 = 1.0
PSA 4/09 at age 43 = 2.9

PSA 4/10 at age 44 = 4.6

FPSA 4/10 = 4.7 and 6%
10/10 = 4.7 and 9%

Biopsy 5/11/10 12 out of 12 negative
2nd Biopsy 7/13/10 12 out of 12 negative
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