Breast radiation

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BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 5/31/2010 5:15 AM (GMT -6)   
My Dr wants me to have my breats radiated (3 treatments) in advance of going on Casodex. Plan is to have me on Casodex for up to 2 years. I know Casodex can cause breast enlargement. Is this standard treatment?
Dx with PC Dec 2008 at 56, PSA 3.4


Biopsy: T1c, Geason 7 (3+4) - 8 cores taken with 4 positive for PCa, 30% of all 4 cores.

Robotic Surgery March 2009 Hartford Hospital, Dr Wagner
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes negitive - tumor volume 9%
nerves spared, no negitive side effects of surgery

One night in hospital, back to work in 3 weeks

psa Jun 09 <.01
psa Oct 09 <.01
psa Jan 10 .07 re-test one week later .05
psa Mar 10 .28 re-test two weeks later .31
psa May 10  .50

Aril 10 MRI and Bone Scan show lesion on lower spine, false positive. 
 
Started HT 5/25/10 with 3 month shot of Trelstar. SRT scheduled for late July


142
Forum Moderator


Date Joined Jan 2010
Total Posts : 6946
   Posted 5/31/2010 6:07 AM (GMT -6)   
I did read about this as a prevention for enlargement, as the booklet mentioned that the enlargement was very difficult to deal with afterwards. Don't have the booklet at hand, but it was one of the Cancer society information handouts.

Carlos
Regular Member


Date Joined Nov 2009
Total Posts : 486
   Posted 5/31/2010 7:13 AM (GMT -6)   
BB,  I found this article on the PCRI web site:  http://www.prostate-cancer.org/pcricms/node/197.  
 
"Radiation to the breast (usually just around the nipples) before the start of testosterone deprivation therapy can reduce the risk of breast growth and tenderness by as much as 65%.17 This is especially important for a man to discuss with his medical provider prior to starting monotherapy with Casodex® or Eulexin®, because of the high incidence of breast growth and tenderness with this type of testosterone blocking treatment."
 
I'm glad you keep asking these questions because I need to learn everything I can, just in case.  Hope this helps.
 
Carlos

Diagnosed 2/2008 at age 71, Gleason score 5+3=8, stage T1c, PSA 9.1. 
Robotic surgery 5/2008, nerves spared, stg. pT2c, N0, MX, R0, Gleason 5+3=8 
PSA <0.1 at 20 months and each test since surgery.


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4223
   Posted 5/31/2010 10:37 AM (GMT -6)   
You can either get your breasts radiated or take Femera or it's generic. Femera is fairly expensive so radiation may be less costly, but Femera works well.
JohnT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 5/31/2010 10:55 AM (GMT -6)   
BB,
I was on Casodex for 2 and a half years. I only experienced some tenderness towards the end and after I stopped the regimen. I no longer have the tenderness. We don't know what long term SE's of mild radiation of the breast area as I know of no study that monitors for morbidity. I do know a few guys who did the procedure and they have no known issues. John's recommendation may be a good one, but I didn't know about it when I started out and I likely still would have avoided taking anything to prevent breast enlargement.

Tony
Disease:
Advanced Prostate Cancer at age 44 (I am 47 now)
pT3b,N0,Mx (original PSA was 19.8) EPE, PM, SVI. Gleason 4+3=7

Treatments:
LARP ~ 2/17/2007 at the City of Hope near Los Angeles.
Adjuvant Radiation Therapy ~ IMRT Completed 8/07
Adjuvant Hormone Therapy ~ 28 months on Casodex and Lupron.

Status:
"I beat up this disease and took its lunch money! I am in remission."
I am currently not being treated, but I do have regular oncology visits.
I am the president of an UsTOO chapter in Las Vegas

Blog : www.caringbridge.org/visit/tonycrispino


BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 5/31/2010 12:19 PM (GMT -6)   
Thanks. This information was helpful.
Dx with PC Dec 2008 at 56, PSA 3.4


Biopsy: T1c, Geason 7 (3+4) - 8 cores taken with 4 positive for PCa, 30% of all 4 cores.

Robotic Surgery March 2009 Hartford Hospital, Dr Wagner
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes negitive - tumor volume 9%
nerves spared, no negitive side effects of surgery

One night in hospital, back to work in 3 weeks

psa Jun 09 <.01
psa Oct 09 <.01
psa Jan 10 .07 re-test one week later .05
psa Mar 10 .28 re-test two weeks later .31
psa May 10  .50

Aril 10 MRI and Bone Scan show lesion on lower spine, false positive. 
 
Started HT 5/25/10 with 3 month shot of Trelstar. SRT scheduled for late July

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