Prostate cancer treatment cuts deaths by 43 percent: long term study- Princess Margaret Hospital

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Veteran Member

Date Joined Jan 2010
Total Posts : 2832
   Posted 6/7/2010 5:27 AM (GMT -6)   
Here are two articles regarding :

"Adding radiation therapy to androgen deprivation significantly improves life expectancy in men with locally advanced prostate cancer, according to results of a long-term study reported here today in an oral session at the 2010 Annual Meeting of the American Society for Clinical Oncology (ASCO)." -

This study was by Padraig Warde, MBChB, Princess Margaret Hospital/University Health Network, Toronto, Ontario.

It is so encouraging to see more news about advances in treating prostate cancer - see my previous posting about PMH - and nice to toot the Canadian horn !


Wishing you all the best.


p.s. did not see squirm's posting before submitting this topic
Age: 54 - gay - with common-law spouse of 13 years, Steve - 60
PSA: 04/2007- 1.68 - 08/2009 - 3.46 - 10/2009 - 3.86
Confirmation of Prostate Cancer: October 16, 2009 - 6 of 12 cancerous samples , Gleason 7 (4+3)
Doctor: Dr. Mohamed Elharram -Urologist / Surgeon - Peterborough Regional Health Centre
Radical Prostatectomy Operation: November 18, 2009 , home - November 21, 2009
Post Surgery Biopsy: pT3a- gleason 7 - extraprostatic extension - perineural invasion - prostate weight - 34.1gm -
ED Prescription: Jan 8/2010 - started daily 5mg cialis - girth back to normal -but not much length - will go for trimix in April when I see doc
Incontinence: Feb 2010- 3-5 pads/1-2 clothes changes/day- March 3, 2010 - week 14 after surgery -finally seeing improvement - March 29- incontinence better - 1-2 pads a day - one pad at night - May 25 - 1 pad during day - 1 pad at night for security (barely needed at all) - stress incontinence at work - lifting trees and shrubs...
location: Peteborough, Ontario, Canada
Post Surgery-PSA: - April 8, 2010 - 0.05 - I am in the ZERO CLUB - hooorah!
Next PSA - October 8, 2010 - TBA -

Post Edited (tatt2man) : 6/7/2010 5:34:32 AM (GMT-6)

Opa N
Regular Member

Date Joined Sep 2009
Total Posts : 150
   Posted 6/7/2010 6:33 AM (GMT -6)   
That was my treatment protocol.
Age 67 at diagnosis. Treated for coronary artery disease (CAD) since 1998, and under control with medications.
2/6/09 Routine physical, with DRE and PSA Test. PSA 4.02. Referred to Uro
4/20/09 TRUS w/needle biopsy
4/23/09 Diagnosis PCa with Gleason 4+3 in 2/2 cores, Gleason 3+3 in 5/10 cores.
CT scan and Bone Scan both negative. Stage T2C.
8/27/09 DaVinci RP at WakeMed Cary NC with Dr. Tortora. Discharged 8/28.
9/8/09 Catheder removed. Path post-surgery confirms PCa, with Gleason 3+3 with scattering of 4. Positive margins in L & R posterior, R and L seminal vesicles, with perineural invasion. Stage T3b.
9/30/09 PSA Post-Op <0.01. Met w/Uro/Surgeon to review surgery and path report. Referred to Medical Oncologist and Radiation Oncologist. Appointments set for 10/8.
10/8/09 Met w/ both oncologists. Adjuvant Combination Therapy to begin ASAP.
10/21/09 First Lupron injection. 30 mg dose (4 month)
11/2/09 PSA 2-month <0.01. Cystoscope w/calibration and dilation to remove scar tissue from urethra. Big relief.
12/18/09 psa 4-Month <0.01 undetectable. MRI/CT scan set for 1/5/10 for IMRT planning. RT to begin week of 1/11/10. Anticipate 64-66 grays over 32-33 treatments.
1/14/10 Start RT with 32 treatments # 2 gys per.
2/26/10 IMRT completed.
3/1/10 Second Lupron injection, 30 mg dose (4 month)
5/10/10 PSA 8 month and 2 month post RT <0.01 undetectable

Initial incontinence pretty bad, starting w/6 Depends pants/day. Gradual improvement, with dramatic reduction in leakage around 9/20/09, to 1 pad during the day and 1 at night (for security). Actually totally dry at night. After 1/16/10 down to a female regular pad. Barely felt. 4/30/10 threw pads away. Dry at last.

Regular Member

Date Joined Nov 2009
Total Posts : 206
   Posted 6/7/2010 11:02 AM (GMT -6)   
That's pretty well my program as well so
this is encouraging reading.
Thanks Bronson !

Age, only 71.
July 2009, PSA 9.1, free ratio 0.16
September GLEASON 4+4=8, T2A
Prostate 44cc.
Calcium: 2.46  (range: 2.20 - 2.65 mmol/L)
25 Hydroxy Vitamin D: 102 (range: sufficiency:
76 - 250 nmol/L)
Bone Scan: Negative
CT Scan scheduled for Dec. 1st. Negative.
Started Casodex 50mg. on Nov. 6, first pill of 30.
Got Lupron 22.5mg ( 90 day ) on  November 19.
No real side effects as of Dec. 15 except dry skin and hair but getting quite 'porky' in the belt area even though now I go to the gym, three times a week. Also I dont have a need to shave anymore so now I can save my 'shaving' allowance and direct it to my stash of Depends !
Christmas Day got my first hot flashes. Thanks Santa!
Open surgery done on Jan. 20th. by Dr. J. Chin at London's University Hospital.
Cath removel scheduled for Feb. 8th. Yes, I know,
that will be 19 days. Dr. is out of country until then.
Pathology Report:
Gleason Score: cannot be determined due to hormone therapy effects. ???????
Extraprostatic Extension:
present, left radial, multifocal
present, left basal, multifocal
Resection Margins:
Apical: involved by invasive carcinoma, multifocal
Bladder Neck: involved by invasive carcinoma, unifocal on left side.Other: non-tumoural prostatic present at resection margin.
Perineural Invasion: present.
Seminal Vesicle Invasion: absent
Lymphovascular Invasion: absent
Lymph Node Status: no malignancy in regional lymph nodes
Additional path. findings:
high grade prostatic intraepithelial neoplasia
Pathology Stage: yp T3a NO MX
Radialogist appointment was on Friday Feb. 26 with Dr. Glenn Bauman in London.
Got another Lupron 90 day shot today and he wants to start IMRT soon. CT Scan plus measure scheduled in about 3 weeks. ( march 15)
First PSA test since surgery on March 18th.
with the results of <0.03 !!!
Started a Facebook page for bikers with prostate issues at:
IMRT to started on May 10. Going to get 33 units.

Post Edited (JB71) : 6/7/2010 11:16:14 AM (GMT-6)

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