Help in understanding FREE PSA numbers.

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New Member

Date Joined Jun 2010
Total Posts : 15
   Posted 6/7/2010 4:53 PM (GMT -6)   
Would love some enlightenment. I just saw the results of my PSA test and PSA is 5.1, down from 25 when prostatitis caused it to skyrocket, nearly six months ago. What i don't understand is the FREE PSA number of .31 What i read seems to say higher numbers better here, but not sure i'm reading it right. Any help?



Post Edited (ge125) : 6/7/2010 4:02:06 PM (GMT-6)

Veteran Member

Date Joined Oct 2006
Total Posts : 1211
   Posted 6/7/2010 8:08 PM (GMT -6)   
Hi Glenne,

Welcome to our site. Sorry that you have to be here, but glad that you found us.
There are several sites that can give a good explanation as to free PSA. here is one of them:

All the best to you.

Born Sept 1936
PSA 7.9
-ve DRE
Gleason's Score 3+4=7, 2 of 8 positive
Open RP 28 Nov 06 (nerve sparing), Post op staging T3a
Gleasons still 3+4=7
Seminal vesicles and lymph nodes clear
Catheter out 15 Dec 06, Dry since 11 Feb 07
All PSA tests in 2007 (4) <.04
PSA tests in 2008: Mar.=.04; Jun.=.05; Sept.=.08; 3 days before Rad Start=0.1
Salvage RT completed (33 sessions - 66 Grays) on the 19th Dec., 08.
PSA in Jan., 09=0.05; July 09=<0.04; JAN 10=<0.04

New Member

Date Joined Jun 2010
Total Posts : 15
   Posted 6/7/2010 8:17 PM (GMT -6)   
Thanks for the link...what seems to be confusing me is the reference to FREE PSA above or below 15 percent. The FREE PSA values posted for me are .31/ng and i can't figure out if this is 31 percent, or less than one percent....I'm sure there is a simple explanation, I'm just not seeing clearly right now.


Veteran Member

Date Joined Sep 2009
Total Posts : 3172
   Posted 6/7/2010 8:43 PM (GMT -6)   
You got it, Glenne. the Free PSA metric is expressed in a percentage of the un-bound (free) PSA in the total PSA. The total PSA is the sum of un-bound and bound PSA. So, 0.31 means 31%.

The higher the free PSA, the more likely that you are free of cancer...31% is a good number.

best wishes...
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