ASCO Meeting in Chicago

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Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 6/7/2010 8:11 PM (GMT -6)   
i didn't go to this one but my friend did. There was no real revelations at the American Society of Clinical Oncology meeting regarding prostate cancer. Some significant studies:

1> Trock et al. This is the study at Johns Hopkins on Active Surveillance and Delayed RP. There is only a small change in Trocks position on AS. It's in the results and conclusion of this link:

"Results: At surgery, men initially managed with AS were significantly more likely to have non-organ-confined tumor (p=0.009) and high-grade tumor (Gleason score ≥ 3+4; p=0.0001) than matched immediate RP men. "

"Conclusions: In the largest cohort to date, AS patients who undergo delayed RP in the absence of biopsy grade progression have similar risk of adverse pathology as matched men who undergo immediate RP. The message to men considering AS must balance the overall low rate of adverse pathology with the knowledge that a small fraction of men upgraded at biopsy will have a potentially noncurable tumor."

What that second quote tells you is that as long as men leave the AS program for RP BEFORE a biopsy indicates adverse results, then they will likely have similar results to an immediate RP guy. The same is not true when a followup biopsy detects a reason to switch off AS.

Glad I didn't have a choice to wait.

Advanced Prostate Cancer at age 44 (I am 47 now)
pT3b,N0,Mx (original PSA was 19.8) EPE, PM, SVI. Gleason 4+3=7

LARP ~ 2/17/2007 at the City of Hope near Los Angeles.
Adjuvant Radiation Therapy ~ IMRT Completed 8/07
Adjuvant Hormone Therapy ~ 28 months on Casodex and Lupron.

"I beat up this disease and took its lunch money! I am in remission."
I am currently not being treated, but I do have regular oncology visits.
I am the president of an UsTOO chapter in Las Vegas

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Post Edited (TC-LasVegas) : 6/7/2010 7:14:48 PM (GMT-6)

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