Highly controversial discussion on DCA~cheap~non-patentable cancer wonder drug? Link~

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zufus
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Date Joined Dec 2008
Total Posts : 3149
   Posted 6/9/2010 7:29 AM (GMT -6)   
It has been used in Canada and Europe and other countries (Sodium Dichloroacetate-DCA), the FDA has made it illegal to even sell it here in USA, has stopped some internet sites from selling it. It is interesting that this drug apparently works on the mitochondria in cells without harming good cells (it appears),and like the P-53 gene which is a known mechanism for PCa (gene) it effects this also to supposedly kill PCa cells or stop there advancement. See this info in the weblink at the bottom, herein.
 
  I cannot say whether this drug is going to be that useful in PCa(or other cancers) or not, there are some claims out there mentioning it as useful but some seem bloggish. The results from the Canadian Hospital that uses this and has discussed it on T.V. a little while back, appears to show it is useful, inexpensive and looks beneficial in many cases for various types of cancers. It is non-patentable unless it is altered or additives maybe used.
 
I kind of believe where there is smoke there is fire, in other words it may have benefits that out weigh the negatives and that is why all the buzz is out there. Our drug companies and their lobbyists, surely don't want to lose money and profits (altruistic intentions that they have for total humanity-LOL), FDA is even questionable on holding back on things that may benefit patients or allowing certain ones priority. I could give examples even. Some company may put additives into this and make up a patent, it seems some company is doing this now I believe I read herein on link. It would have to be outside the USA to get on the market soon, as FDA approval is a super long process.
 
I think for patients that are at terminal risk, you might wish to look at this and decide for yourselves if you wish to try it. If so, make sure you get the pharmaceutical grade and not industrial grade(DCA-acid) and that it is Sodium-DCA, then next you have to figure out or find out about dosing levels and cutting it down...as it may come as  20 grams or more granulated like salt, you cannot take high levels of this...the levels I read about seem to show 20-25 mg's (once or twice a day), so 1000th amount of the bottle, maybe mixed in water prior to taking(this would be a tiny amount). You would have to read all you can about it and make you own decision(s).  If nothing else it makes for an interesting read and worth seeing if results pop up that we can read about or witness or verify.  It also has some side effect risks that one would need to know about if taking such.
 
 
You can surf internet and read whatever on this, from various sources. yeah


Youth is wasted on the Young-(W.C. Fields)

Post Edited (zufus) : 6/9/2010 6:49:20 AM (GMT-6)


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 6/12/2010 9:20 PM (GMT -6)   
Another website information on DCA is:

www.thedcasite.com/dca_faqs.html   (has some questions and answers etc.)
 
Also there are huge differences between DCA (acid) and DCA Sodium, sodium pharmaceutical grade is the only one to even think about using, if one did considering trying it.
 
 

Post Edited (zufus) : 6/12/2010 8:23:29 PM (GMT-6)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 6/12/2010 10:52 PM (GMT -6)   
zufus,

thought the above link was interesting. for someone in the very advance cases, where there is little hope, the use of DCA might offer that glimmer of hope to someone. i thought the warnings in the questions and answers were critically important. especially the mention of toluene. that was one of many toxic materials that i was in daily contact on the job way back in my early 20s when i use to work in the machine shop trades. in those days, there were no MDS sheets or safety warnings to educate a worker, you used what they gave you, and you did what you were told if you wanted to keep your job. i was also exposed to lots of formlydahyde (hard to spell) and acetones on daily basis. hmm, wonder why i have had cancer 4x so far.

glad you are out there keeping tabs on things like the DCA, i pray i never would have to think about being in the situation to need it, but its good to put in the back of the memory in case needed. thanks for posting it.

david in sc
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one:  July
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 31 days, 5/24 put in Cath #17


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 6/13/2010 5:30 AM (GMT -6)   
It is a possible choice among many, I hope to hear reports that it has done great things for PCa patients, time will tell. It also doesn't mean toulene is in the pharamceutical grade of this, there are different sources and methods used to process it appears from the information.
Youth is wasted on the Young-(W.C. Fields)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 6/13/2010 9:38 AM (GMT -6)   
Adding to what I already wrote, I think sometimes the FDA gets a bad name. I am not always happy with their lack of speed in approving needed drugs, etc, but we must all remember that one of their prime purposes is to make sure that the drugs we do use, are safe for the general population. Over my lifetime, the FDA has pulled a lot of dangerous drugs off the market, and prevented other dangerous one from ever hitting the market place. All their calls always right, of course not. Do they move too slow at times, yep. I would hate to live in any country that didn't have an equvinecy of a "FDA" in their structure.
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one:  July
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 31 days, 5/24 put in Cath #17

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