HIFU to you too.

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Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted Today 12:56 PM (GMT -6)   
Guys,
A couple of weeks ago we were talking about HIFU, the reason for ultrasound vs microwaves, and the power level required. Well, while working on my contract job I bumped into this place:

http://www.blatek.com/med_HIFU.aspx (Medical Hifu Transducers | High Intensity Focused Ultrasound | HIFU Transducers | HIFU Ultrasound Transducers | HIFU Transducer Design)
They make the transducers for HIFU and list the necessary drivers, all of which I have in my lab right now. Actually, I exceed all the requirements significantly.

So, if you decide to come to my place for the GFMPH weekend in 3 months, not only can you get a free colonoscopy broadcast on TV channel 19, a TENS treatment high enough to make your teeth hurt, and a low frequency infrasonic acoustic treatment strong enough to cause bowel movements in cattle, you can have a part of your body HIFU 'ed.

I can hear my wife now. "What's that smell? Are you cooking something down there or shall I call 911, again ?" :-)

Jeff
Married 34 years, DX Age 56. First routine PSA test on April 8, 09: 17.8. Start 2 weeks of Cipro to rule out protatitis. May '09 PSA: 22.6, 3 weeks later: PSA: 23.2.
Biopsy 6/10/09: 7/12 scores positive, 20%-70%, Gleason 3+4=7, 3+3=6. Bone and C/T scans neg.
RP DaVinci -7/21/2009 @ Univ of Roch Medical Center
Left nerve gone, right partial spared.
Catheter removed - 7/31/2009 Pathology report received:
Gleason 3+4=7, Tumor size: 2.5 x 1.8 cm, location: both lobes and apex.
Extraprostatic extension present; Perineural invasion: present, extensive.
No Malignancy in Seminal Vesicle, vasa deferentia, lymph nodes 0/13
Prostate mass 56 grams. Pathologic Stage: pT3aN0MX
Post Surgery Status:
Potency - 12/11 5 months, Still no activity, zip. Using pump daily since 11/11. No effect with 20 mg of Cialis or 100 mg of Viagra. Shots next See Uro 1/22/10 Trimix #1. Try 0.08- 25%, 0.12-25%, 2/26/10 try 0.16 First Success! 90%.
Incontinence - 8/20 4 full pads per day
.. 9/7 3-4 full pads per day. Try controlling fluids.
12/11/09 5 months: 3 pads per day, 400-450ml/day
02/26/10 7 months: 3 pads but leak is now 320 ml (5 day avg.)
03/22/10 8 months: 3 pads per day, 280 ml/day (5 day avg.) PT says all muscles are tight and working properly. There must be another issue. Uro mtg 4/23.
5/22/10 10 months: 2 pads per day, 190 ml/day Scope on June 15 Short sphincter
Post Surgery PSA - 9/3 6 weeks - 0.05; 10/13 3 months - 0.04, 1/14 6 months - 0.05, 4/14 9 months - 0.04 and <0.01 with ECLIA.


Opa N
Regular Member


Date Joined Sep 2009
Total Posts : 150
   Posted Today 1:06 PM (GMT -6)   
Who wouldn't show up for all that!
Roger
Age 67 at diagnosis. Treated for coronary artery disease (CAD) since 1998, and under control with medications.
2/6/09 Routine physical, with DRE and PSA Test. PSA 4.02. Referred to Uro
4/20/09 TRUS w/needle biopsy
4/23/09 Diagnosis PCa with Gleason 4+3 in 2/2 cores, Gleason 3+3 in 5/10 cores.
CT scan and Bone Scan both negative. Stage T2C.
8/27/09 DaVinci RP at WakeMed Cary NC with Dr. Tortora. Discharged 8/28.
9/8/09 Catheder removed. Path post-surgery confirms PCa, with Gleason 3+3 with scattering of 4. Positive margins in L & R posterior, R and L seminal vesicles, with perineural invasion. Stage T3b.
9/30/09 PSA Post-Op <0.01. Met w/Uro/Surgeon to review surgery and path report. Referred to Medical Oncologist and Radiation Oncologist. Appointments set for 10/8.
10/8/09 Met w/ both oncologists. Adjuvant Combination Therapy to begin ASAP.
10/21/09 First Lupron injection. 30 mg dose (4 month)
11/2/09 PSA 2-month <0.01. Cystoscope w/calibration and dilation to remove scar tissue from urethra. Big relief.
12/18/09 psa 4-Month <0.01 undetectable. MRI/CT scan set for 1/5/10 for IMRT planning. RT to begin week of 1/11/10. Anticipate 64-66 grays over 32-33 treatments.
1/14/10 Start RT with 32 treatments # 2 gys per.
2/26/10 IMRT completed.
3/1/10 Second Lupron injection, 30 mg dose (4 month)
5/10/10 PSA 8 month and 2 month post RT <0.01 undetectable

Initial incontinence pretty bad, starting w/6 Depends pants/day. Gradual improvement, with dramatic reduction in leakage around 9/20/09, to 1 pad during the day and 1 at night (for security). Actually totally dry at night. After 1/16/10 down to a female regular pad. Barely felt. 4/30/10 threw pads away. Dry at last.


el perro
Regular Member


Date Joined Mar 2010
Total Posts : 46
   Posted Today 1:28 PM (GMT -6)   
Are you a mad scientist at your day job too?

Here is another HIFU application you might be interested in... not actually heating tumors, just shaking them up. Here's a report on it from DUke Univ. from a couple years ago.

medicalphysicsweb.org/cws/article/research/30847

Seems like it might be a little gentler than the cooking approach.
Dx 11/2008, Gleason 3+3
Active surveillance for now


Sleepless09
Veteran Member


Date Joined Jul 2009
Total Posts : 1267
   Posted Today 1:44 PM (GMT -6)   
Jeff, you're exactly the sort of person I know I'd love having dinner with. Some of your offerings, however, I'm not so sure about. The one that causes cattle to let loose, and nothing lets loose like cattle, in particular sounds like a bad blast. I can see why your wife would have 911 on speed dial.

Sheldon AKA Sleepless
Age 67 in Apil '09 at news of 4 of 12 cores positive T2B and Gleason 3 + 3 and 5% to 25% PSA 1.5
Re-read of slides in June said Gleason 3 + 4 same four cores 5% to 15%
June 29 daVinci prostatectomy, Dr. Eric Estey, at Royal Alexandra Hospital Edmonton one night stay
From "knock out" to wake up in recovery less than two hours.  Actual surgery 70 minutes
Flew home to Winnipeg on July 3 after 5 nights in Ramada Inn  ---  perfect recovery spot!
Catheter out July 9
Final pathology is 3 + 4 Gleason 7, clear margins, clear nodes, T2C, sugeron says report is "excellent"
 
Oct 1st 09 -- dry at night, during day some stress issues.
Oct 31st padless 24/7 
 
First post op PSA Sept 09  less than 0.02
PSA on Oct 23 test again less than 0.02
PSA on Jan 8 less than 0.02
PSA on April 9 less than 0.02 
 
  


Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted Today 2:35 PM (GMT -6)   
Hey El perro. I hate to admit it but I actually get paid to do some of the crazy stuff. I just tend to push it a little more than the usual.

Sheldon, Quite frequently my wife is the "Designated Dialer" for some experiments. The woman is a saint.

Roger, I promise to use K-Y jelly. My scope is was better than the Uro's1. Smaller diameter, better lighting, higher resolution. He was able to inject saline into my bladder which is something mine cannot do. He also had lidocaine - I don't. That's why I'm not offering free cystograms in the package. ;-)

Jeff

Post Edited (Worried Guy) : 6/27/2010 7:51:48 AM (GMT-6)


Paul1959
Veteran Member


Date Joined Nov 2007
Total Posts : 598
   Posted Today 2:48 PM (GMT -6)   
With that offer, wild horses could not keep me away from the second annual GFMPH weekend in September. I have priced tents and have bought my sleeping bags. I am all set. I'm also bring salves, bandages and an awful lot of toilet paper.  Anyone wanna car pool from Metropolitan New York area?
Paul
www.franktalk.org ED website for PCa guys

46 at Diagnosis.
Father died of Pca 4/07 at 86.
10/07 PSA 5.06 (Biopsy 11/07 1 of 12 with 8% involvment) (1mm)
Da Vinci surgery Jan 5, '08 at Mt. Sinai Hosp. NYC www.roboticoncology.com
Saved both nerve bundles.
Path Report: Stage T2cNxMx
-Gleason (3+3)6
Pad free on March 14 - (10 weeks.) Never a problem since.
ED - at one year, ED is fine with viagra.
Two year PSA - undetectable!


Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted Today 6:31 PM (GMT -6)   
Hey Paul,
Where do you think you're heading? A third world country? We have plenty of water, toilets, toilet paper and pee pads. Can easily support a group of 80.
We have that many during our annual July 4th party - and half of them are shooting guns at our range. Haven't lost anyone yet. No problem. A bunch of prostateless funny guys is easy. I still smile when I think of last year. By the way, the Ingmar Bergman house is still up for sale.

I have added quite bit of equipment since the last time you were here. Fun toys. I'll see if I can slip a HIFU transducer in. We can always use it to cook the hamburgers.

Mark your calendars, boys.
Jeff

Paul1959
Veteran Member


Date Joined Nov 2007
Total Posts : 598
   Posted Today 8:05 PM (GMT -6)   
I'm bringing toilet paper for when you create that sound that makes cows poop and you have it aimed at me.

OK. How many guys are coming to this GFMPH weekend? It is worth the trip. This time we hope it won't rain. Jeff has a bon fire to end all bon fires ready to go!

Guys, you need to come. Tell your wife it Good For Men's Prostate Health.
Paul
www.franktalk.org ED website for PCa guys

46 at Diagnosis.
Father died of Pca 4/07 at 86.
10/07 PSA 5.06 (Biopsy 11/07 1 of 12 with 8% involvment) (1mm)
Da Vinci surgery Jan 5, '08 at Mt. Sinai Hosp. NYC www.roboticoncology.com
Saved both nerve bundles.
Path Report: Stage T2cNxMx
-Gleason (3+3)6
Pad free on March 14 - (10 weeks.) Never a problem since.
ED - at one year, ED is fine with viagra.
Two year PSA - undetectable!


mvesr
Veteran Member


Date Joined Apr 2007
Total Posts : 823
   Posted Today 8:18 PM (GMT -6)   
Hi Jeff

I'll take a cheeseburger well done with onion rings.

Mika
age at dx 54 now 58
psa at dx 4.3
got the bad news 1/29/07
open surgery Duke Medical Center 5-29-07
never more than 2 pads
ED is getting better
the shots work great, still can't give them to myself
three years of zero's
Retired again after 36 years February 1, 2010


Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 6/26/2010 9:30 AM (GMT -6)   
I will have to try this experiment with prostates -Western Digital Research Paper .
Jeff

Cajun Jeff
Veteran Member


Date Joined Mar 2009
Total Posts : 4106
   Posted 6/26/2010 11:35 PM (GMT -6)   

Jeff: Will be booking my ticket as soon as I get home for the great wkend. 

 

El Pero:  I have been to Jeff's home and I have certified that he is in fact a mad scientist!  LOL

 

Cajun Jeff


9/08 PSA 5.4 referred to Urologist
9/08 Biopsy: GS 3+4=7 1 positive core in 12 1 pre cancer core
10/08 Nerve-Sparing open radical
Surgery Path Report Downgrade 3+3=6 GS Stage pT2c margins clear

3 month: PSA <0.1
6 month: PSA <0.1
10 month:PSA <0.1
1 year: PSA <0.1
16 month:PSA <0.1

ED - Started Cialis at 3 months, tried all 3, 6 months added pump, 9 months Tried MUSE (YUCK) Bad experience.
1 year mark Found new Urologist visit was at 14th month post surgery
Started Injections, Caverject! (Success)
17 month: ED making improvements : Oral Meds gets me 85%


Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 6/27/2010 7:48 AM (GMT -6)   
"Mad Scientist", huh. I prefer to think of myself as an "Enthusiastic Researcher".

Hey Cajun Jeff,
After you left we got an email and follow up call from the contract officers saying they wanted to visit the facility. We cleaned up the family room and put all the electronics in there. From my seat at the kitchen table, I can look outside and watch the deer in the orchard and then look to the right and see more scopes, analyzers, and wave generators than NASA.

My poor, poor wife...

Jeff (the leaking one)
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