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Waitman
New Member


Date Joined Jun 2010
Total Posts : 10
   Posted 6/30/2010 9:20 AM (GMT -6)   
Doctor called and said 1 of the 12 biopsy samples showed cancer, Gleason of 6. He mentioned i was a canadate for seed implants. Any of you folks had that procedure, Comments? Troy

April6th
Regular Member


Date Joined May 2010
Total Posts : 264
   Posted 6/30/2010 9:52 AM (GMT -6)   
Troy,

I haven't had the seeds (but one of my best friends did and is very happy with his choice).

Just curious....did your doctor only give you that one choice for your treatment?

Good luck!

Dan
Here are some of my stats:
Age:54
Father diagnosed with PC at age 72 - wasn't contained to prostate when found in 1992.
My PSA rose from 3.2 to 5.1 over the course of 1.5 years with Free PSA at 25% for the last two tests.
DRE showed no evidence of tumor but Uro thought my prostate was a little large for someone my age
PCa diagnosed 4/6/10 after biopsy on 4/1/10
1 out of 12 biopsy samples was positive with 5% of biopsy sample cancerous
Gleason 3+4
Da Vinci surgery on 6/1/10
Pathology report shows cancer confined to prostate and all other tissue clean


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4225
   Posted 6/30/2010 9:52 AM (GMT -6)   
Troy,
What was the % of the core positive? What is your psa? Did he feel a nodule? Please get a 2nd opinion on you biopsy slides from an expert, either Epstien or John Hopkins or Bostwich at Bostwich labs. It may not even be PC. From what you have described you may have a very low grade indolant type of pc that may never need any treatment. Please do a lot of research on Active Surveillance and get a doctor that is familiar with it ans it may be your best option. It involves getting another biopsy and regular psa tests and if there is any sign of progression you can be treated with the same result if you were treated immediately. 70% of those with your low stats never progress.
Brachytherapy is an outpatient procedure and is usually without the side affects commonly associated with surgery, incontinence, and impotance. It has a very long track record of producing excellent results, many 15 to 17 year studies and many of these studies show superior results to surgery. It is a viable option, by why get treated at all if you don't need to.
If you do choose Brachy, get a Brachytherapist that has done at least 500 procedures and is well known. I'm 1 year out from being seeded for high risk PC and have no side affects.
JohnT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


JoeFL
Regular Member


Date Joined Oct 2009
Total Posts : 420
   Posted 6/30/2010 10:38 AM (GMT -6)   
Troy,
 
First, reread John T's post above. You may not need to do anything any time soon. After making that determination, and if you decide on seeds, here is my answer:
 
I chose seeds along with 25 treatments of IGRT. I had minimum side effects and was back into my normal routine within 2-3 days. (see my stats below) I have been very happy with my decision and the results of my first (and maybe too early) post radiation PSA test. There have been several other members who have recently had BT who will probably also weigh in.
 
Learn all you can, explore all options, do what feels right to you. Best wishes on the journey.
 
Joe
 
 

Age -67 PSA - 4.5

Biopsy  (9/4/09) - Positive in 5 of 8 cores. In those 5 cores, 5 of 11 samples were positive. Gleason 3+3=6. Stage – T1C  Ct and Bone scans negative.

 

BT performed on 12/11/09. 84 seeds of Palladium 103. Surgery at 7:30 - Home at 12:30 same day with no catheter. Blood in urine for a week. Side effects as expected -  some burning, frequency, urgency.   Resumed daily  1 ½ mile walk after 3 days. 

 

BT followed with 25 IGRT treatments beginning Feb 15 (4500 Gy's). After third week, experienced some fatigue. Now 2 months from last rad treatment - energy level has returned. Burning gone and urgency is much improved.

 

First post treatment PSA (6/1/10) - 0.1

 


RayPat
Regular Member


Date Joined Apr 2010
Total Posts : 104
   Posted 6/30/2010 11:07 AM (GMT -6)   
Troy, I had seeds implanted last Tuesday. As far as the procedure no big deal since I was totally out of it. The urologist who assisted likes to send the patient home with a catheter for 36 hours. Next day some swelling at point of needle insertion but not much pain. I hated the catheter. A very small amount of blood in my urine but only for one day. Took the catheter out two days later and that night I was in ER having one put back in. Finally got it out yesterday. In a nut shell, there was more discomfort to the entire experience than I expected but certainly much less than surgery would have been. If you can avoid being cathed for a week it's no big deal.
Age 63

01/26/10 ...PSA 9
Referred to urologist
Met urologist on 2/26/10....DRE normal new PSA test was 11. Taken after DRE.
Biopsy on 3/26/10. 14 samples...3 positive on right side...all 11% Gleason 3+3
Urologist said stage T-1c.
Advised treatment. Discussed surgery and set appointment with radiologist for 4/26/10
4/26/10 Met with radiologist. Thinks IMRT or Brachytherapy would be good choice.
5/20/10 volume study done all looks good for Brachytherapy.
6/22/10 Brachytherapy done.
6/24/10 Catheter out...pretty good flow most of day until 3:30 then stopped
Off to ER for new one. :>(


geezer99
Veteran Member


Date Joined Apr 2009
Total Posts : 990
   Posted 6/30/2010 7:58 PM (GMT -6)   
As you can see, I am a surgery guy but my younger brother did watchful waiting for 4 years and then went for seeds at age 55 and now 6 years later he reports no evidence of PCa and that Viagra takes care of any problems. (Our dad had PCa too)

Your stats make seeds or watchful waiting are reasonable choices. They have much less side effects than surgery or more aggressive radiation
Age at diagnosis 66, PSA 5.5
Biopsy 12/08 12 cores, 8 positive
Gleason 3+4=7
CAT scan, Bone scan 1/09 both negative.

Robotic surgery 03/03/09 Catheter Out 03/08/09
Pathology: Lymph nodes & Seminal vesicles negative
Margins positive, Capsular penetration extensive Gleason 4+3=7
6 weeks: 1 pad/day, 1 pad/night -- mostly dry at night.
10 weeks: no pad at night -- slight leakage day/1 pad.
3 mo. PSA 0.0 - now light pads
6 mo. PSA 0.00 -- 1 light pad/day
9 mo. PSA 0.00 -- 1 light pad/day ED remains
12 mo. PSA 0.00 -- still one light pad and ED


erbob
Regular Member


Date Joined Jan 2010
Total Posts : 281
   Posted 7/1/2010 10:30 AM (GMT -6)   
Eighty Iodine seeds were implanted in my old prostate exactly five weeks ago yesterday. Procedure was "a piece of cake" for me and went home without a catheter about two hours after the seeds were implanted. No problem peeing at all with the exception of the expected small amount of blood for a few days.
No real discomfort after the procedure and accomplished a trip of about 1,200 miles from the Chicago area to my home in Colorado on the second day after the procedure - with me at the steering wheel for the entire trip. Next PSA to be taken at the end of August.
Troy, good luck with which ever method/procedure you finally decide to go with.
Bob, located in Southern Colorado

Age 73 Retired Railroader.
Dx Jan 2010, Volume 51.345
Gleason 3+4=7, second opinion 4+3=7 (Don't know which to believe)
PSA
2.6 4/96.......... 3.7 4/07
1.9 5/97.......... 3.2 1/08
2.3 4/98.......... 6.1 4/09
2.2 10/99......... 5.3 5/09
2.4 8/00......... 5.3 8/09
2.3 6/01......... 6.9 10/09
2.9 2/03......... 7.3 12/09
3.6 4/04......... 6.1 1/10
3.0 5/05......... 5.0 3/10
4.7 4/06......... 0.7 5/10 (Lupron/Bicalutamide)
Volume study at CPCC (Westmont, IL) Feb 15, 2010 = 55.7cc
On Feb 15, 2010 put on 90 days of Bicalutamide
Got LHRH Lupron shot on Feb 29,2010
Another Volume study May 24, 2010 = in mid-40cc
BRACHYTHERAPY received May 26, 2010
Received 80 I-125 (Iodine seeds)
Activity per seed (mCi) 0.373
Total activity implanted (mCi)29.80
Measured exposure @ 3 feet (mR/hr) 0.06
Received the Brachytherapy at the Chicago Prostate Cancer Center from Dr. Brian Moran
Walked in the facilty and just a few hours later walked right out.
No after effects other than just a little sore from the needle sticks but NOT serious
enough to take ANY meds for pain.
PSA to be taken in three months (Aug 2010).

Post Edited (erbob) : 7/1/2010 4:14:27 PM (GMT-6)


Tudpock18
Forum Moderator


Date Joined Sep 2008
Total Posts : 4151
   Posted 7/1/2010 3:14 PM (GMT -6)   

Dear Troy:

I can't really improve on the very excellent advice given by JohnT.  For a little first person info on seeds feel free to select the link in my signature to hear about my "journey".  I'm 1 1/2 years post-procedure with zero side effects.  Should you ultimately determine that treatment is necessary I am a strong advocate of brachytherapy and or brachytherapy/radiation as the cure rates are generally equal to surgery with much less onerous side effects.

Good luck and please keep us posted,

Tudpock (Jim)


Age 62, Gleason 3 + 4 = 7, T1C, PSA 4.2, 2 of 16 cores cancerous, 27cc
Brachytherapy December 9, 2008.  73 Iodine-125 seeds.  Procedure went great, catheter out before I went home, only minor discomfort.  Regular activities resumed, everything continues to function normally as of 4/10/10.  6 month PSA 1.4 and now 1 year PSA at 1.0.  My docs are "delighted"!

Waitman
New Member


Date Joined Jun 2010
Total Posts : 10
   Posted 7/6/2010 6:50 AM (GMT -6)   
I have been reading about seed inplants. Has anyone experienced the type where the seeds are taken out after treatment? Also, is my wife at risk of radiation poising during sex after the procedure? Can cancer be passed along throug blood exchanges. Troy.

zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 7/6/2010 7:00 AM (GMT -6)   
Excellent as usual from John T a very well informed PCa patient, dido for his suggestions you don't know enough about what your total options are yet. You might even fit the criteria for "Indolent PCa" as defined by John Hopkins Hospital-Brady Urology Div., wonder if your doc would even tell you that??? Alot of patients rushed into treatments with more than your best interests at heart. Beware of bias, agenda, and cashin on the patient...to much of that happening all the time. Nothing wrong with brachy seed idea, just more importantly define what you have first, then all options to deal with it and hopefully you get a say in what happens to your body...as you should. Lots of ways to treat this many can be equally successful. My brother has indolent PCa, no treatment now for 5 yrs. and no psa increase and was low originally at 1.1 anyway (67 yr.s old now). He was told to get surgery, now he and his doc laugh at that when comes in for psa tests. Interesting how that tone changed, too. His choice and when time comes can still chose his options. Meanwhile do think he likes being a man and normal??? What is that worth?
 
Get the actual copy of your pathology report, yours by law, demand copy from uro-doc or whomever has it, then post what it says herein and learn what it says upon it, probably wasn't done by the leading expert pathologists John mentioned, perhaps the uro-docs are still in the dark ages as to what is what with pathology. Since pathology is probably the single most important factor in your treatment, why not a second opinion even always!
 
Go get other opinions too, this is not the flu or simplistic disease to deal with.


Youth is wasted on the Young-(W.C. Fields)

Post Edited (zufus) : 7/6/2010 7:15:38 AM (GMT-6)

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