Link and a quick mention of Ketoconazole for HRPCa or primary PCa

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zufus
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Date Joined Dec 2008
Total Posts : 3149
   Posted 7/9/2010 10:44 AM (GMT -6)   
What is Keto:   I believe I recently read that it was approved like in the 1980's and was  not for PCa, but as some kind of fungal treatment thingy (ha). It was later found to be very useful on PCa, and used fairly often today for second line hormone therapies, when the other stuff you all know of has failed  (LHRH drugs and/or casodex etc.)
 
You can get HDK (high doseage keto) or normal doseage keto. It acts like ADT but works as a barrier and controls secretions form the endrocine glands and dimishes the production of testosterone, it hinders an enzyme called P450. In lab settings proven ability to kill PCa cells. Apparently works similar in patients, as with any drug we know of...doesn't kill all the prostate cancer cells, or these PCa stem cells survive (a guess), the older cells die off is maybe what is happening.
 
It is found to work better with Hydrocortisone added with, so most docs prescribe it this way. HDK keto protocol is like 3x a day the first week, 200mg., then raised to double strength, same times, best on empty stomach, between meals, absorbtion is better this way. This will work on HRPCa, how long varies as does all HRPCa protocols (too many patient variables).  Cost in Canada (your discounted price)  (also called Nizoral-generic)  200 mg- 100count=  $129, probably double that in the States here.  There are some possible side effects and you can read about them, generally patients say it isn't all that bad to take from the ones I heard from or about.  You might want to look at this way before chemo protocols and other things too. 
 
Link on this today:  http://ezinearticels.com/?Prostate-Cancer-Patients-Have-A-Brighter-Future-With-Ketoconazole  (google it or search other sites on Keto)
 
Also  www.hrpca.org  (has info on second line therapy drugs including this one)
 
 
Youth is wasted on the Young-(W.C. Fields)

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