Thank you Sleepless, Aimzee and Tony for your recent comments.
Unfortunately I have done some research on husbands situation and the research isn't good. The minimum recommended margin of healthy tissue for Squamous cell carcinoma (SCC) is 4mm.(Again the second GP is wrong!!) My husband has 0.3mm. This is why the hand is a terrible place to get SCC as it has little removable flesh and is prone to recurrence and metasteses. See text below copied from an article on the internet. My husband's SCC was in the interdigital cleft (the area in between the knuckles).
"Haws et al2 reported a 0.1% to 3% rate of metastasis for squamous cell carcinoma of sun-exposed skin. However, squamous cell carcinoma of the hand is associated with a higher risk of metastasis compared to squamous cell carcinoma of the skin in other regions of the body, having been reported to metastasize in 5.5% to 28% of cases.
In 1981, Rayner described the “danger zone” of the hand to include the dorsal skin of the proximal phalanges, interdigital clefts, and the first webspace. He noted that tumors in this region of the hand were associated with an increased incidence of local recurrence and metastasis when compared to other regions of the hand. The 5-year survival rate for metastatic squamous cell carcinoma is 20% to 40%."
So the question really is whether this situation overrides the RP situation in terms of needing to get fixed and in that case perhaps we will need to move the surgery dates.
I feel helpless and overwhelmed. Any ideas on what we should do next are appreciated.
Husband's age: 52. We live in Sydney Australia.
In 2007 my husbands PSA level was 2.5.
In Feb 2008 it was 1.7
In Oct 2009 it was 3.67 with a free PSA ratio of 27
In Feb 2010 it was 4.03 with a free PSA ratio of 31.
In June 2010 it was 2.69
Biopsy 28/4/2010: results, negative for a diagnosis of PC however 3 focal ASAPs on left side of prostate at base, apex and at transition resulting in the conclusion "...small acinar proliferation is suspicious but not diagnostic for prostatic adenocarcinoma."
Review of biopsy by experienced pathologist, results,
1 out of 12 core diagnosed with 10% of Gleason score 3+3 cancer (left transitional)
1 out of 12 cores with ASAP (left apex), suspicious but not diagnostic of cancer
Next steps: Nerve sparing RP on 20th August 2010.
My husband's maternal grandfather died of prostate cancer at 72. His maternal uncle died of prostate cancer at 60. Because he is the third generation to be diagnosed he has hereditary PC.
Post Edited (An38) : 8/7/2010 7:26:26 PM (GMT-6)