Now two types of cancer to deal with

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An38
Veteran Member


Date Joined Mar 2010
Total Posts : 1148
   Posted 8/6/2010 7:12 AM (GMT -6)   
This has been a very difficult day.
 
My husband is due for RP surgery on the 20th and today he dropped in to his GP to get the results of a wart removal on his hand he had nearly 2 months ago. With all the prostate cancer stuff we hadn't thought about it very much but wanted to get it out of the way before surgery. (It's unbelievable the GP never called to tell him the result, this is just a repeat of our experience with the urologist. I will never trust a doctor again)
 
Unfortunately it was cancer, and as I was not there during what I thought was a routine appointment I don't know how bad it was and whether the margins were positive or not. All my husband  heard was that it was deep and also that the GP said to watch the site to see if anything changes. The doctor definately did not say if the margins were clear on not, only that he cut out as close to the bone as possible so it was as deep as possible. And its Friday evening here and he hasn't got the pathology report.
 
The fact that my husband has a skin cancer is not surprising, we do live in Australia where 50% of the population gets skin cancer at some point. And my husband is of Irish descent with pale skin and blue eyes. But, given it looked like a wart, its probably a squamous cell carcinoma and that is the bad version and we are not going to get the path report till next week just is going to make this a bad weekend.
 
I sobbed when I heard, it feels like we are coping with too much at once. In less than three months my husband has been diagnosed with two different types of cancer. I really hope they are not linked. CANCER SUCKS!
 
An
Husband's age: 52. We live in Sydney Australia.

In 2007 my husbands PSA level was 2.5.
In Feb 2008 it was 1.7
In Oct 2009 it was 3.67 with a free PSA ratio of 27
In Feb 2010 it was 4.03 with a free PSA ratio of 31.
In June 2010 it was 2.69

DRE normal.
Biopsy 28/4/2010: results, negative for a diagnosis of PC however 3 focal ASAPs on left side of prostate at base, apex and at transition resulting in the conclusion "...small acinar proliferation is suspicious but not diagnostic for prostatic adenocarcinoma."
Review of biopsy by experienced pathologist, results,
1 out of 12 core diagnosed with 10% of Gleason score 3+3 cancer (left transitional)
1 out of 12 cores with ASAP (left apex), suspicious but not diagnostic of cancer

Next steps: Nerve sparing RP on 20th August 2010.

My husband's maternal grandfather died of prostate cancer at 72. His maternal uncle died of prostate cancer at 60. Because he is the third generation to be diagnosed he has hereditary PC.

BobCape
Regular Member


Date Joined Jun 2010
Total Posts : 416
   Posted 8/6/2010 7:33 AM (GMT -6)   
So sorry to hear that An. It certainly is not fair, and it doesn't sound like the doctors have been very effective in providing information to you folks. I can only suggest that you keep the faith and dont let this tear you guys up. I remember 1st learning of my pc, and how it seemed like all was lost. Then we find out there are options, and it doesn't have to be the end of the story. I hope that is the case for you and your husband. I'm sure you both have a lot of fight left before you're willing to give up. I know I will say a prayer for you both.
First ever PSA test Jan 2010 @ 51 years old. 4.0.
Digital exam in March 2010 showed 1 side hard, other soft.
Biopsy, positive in 3 of 12.
Davinci @ Boston Medical Center, May 17, 2010.
Was suggested prior to it was likely contained.
June 1 advised 3+-4 was really 4+3 per pathology. Pos margins.
Listed on patholgy as PT3, but with extraprostatic extension,
microscopic invasion of the bladder neck, PT3A is perhaps the case.
Catheter removed June 1.. 1 pad/day, doing ok. ED, but not in rush.
Sore as heck down there, but doing much walking with my wife.
To meet with my Uri (1st meeting since) June 17 - 1 mo point, to discuss.
BMC already has me setup to meet with radiology.
Felling a little better each day. Cant tell if my expectancy just went from 10-15 down to 5-7, the information out there appears to be all over the place. I WILL NOT radiate my insides to the point of being a veg for the sake of a few years. QOL is primary to me. Selfish I guess. I pray for all of you as I do for myself, but must remember that i've had a pretty good 50+ years, and know others who have lost their children to disease.. so I dont have the nerve to complain! Update 7/14/2010: When I tried changing this sig a few days after creating it, system was broken. My new rad oncologist are discussing IMRT.. though he says he can see why waiting a bit and watching the PSA on super sensitive basis might make sense. I am leaning towards IMRT.. thinking is my body is pretty strong now, i'm 51, and if I can rid my body of this while trying to minimize the side effects.. I dunno. No really Good answers. When I said I didnt want radiation to the point of being a veg.. I really meant there is a limit as to where I wish to go in order to realize only a small increase in life expectancy.. and not that I am an unreasonable person. I do, after all, have an obligation to my wife and kids.

Sephie
Veteran Member


Date Joined Jun 2008
Total Posts : 1804
   Posted 8/6/2010 7:51 AM (GMT -6)   
Oh An, I was so sorry to hear about this latest news. Don't fret too much...squamous cell is not the worst skin cancer - melanoma is. And don't jump the gun about it being squamous...basal cell (which I've had) can also look like a wart and is more common. In my case, I have a 2 inch scar on my right shoulder from a large patch that was removed about 7 years ago.

As to why the GP never called with the results is inexplicable...may I ask why your husband wasn't referred to a dermatologist as they can usually tell just by looking at something what it is? I see my derm every year for a full body check and have been a couple of times in between visits to have him to "look at" something that concerned me. Fortunately, no recurrences of skin cancer but lots of age spots that have had to be removed for biopsy.

As to whether or not your husband's PCa and skin cancer are related, put that thought out of your mind. One has nothing to do with the other.

I know you are worried about the prostatectomy and I won't tell you not to worry because I've been where you're going and know all too well what it feels like to stand by and watch this happen. I hope that you will find the strength and courage you need to get yourself and your husband through this.
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (solitary focus of extraprostatic extension). Perineural tumor infiltration present. Apex margin, bladder neck and SVs negative. Final Gleason 3+4. PSA: 0.0 til July 2009. August 2009 - 0.1, September 0.3, October back to 0.0, December 0.0, March 2010 0.0. Next PSA in 6 months. Thank you God!

LV-TX
Veteran Member


Date Joined Jul 2008
Total Posts : 966
   Posted 8/6/2010 7:54 AM (GMT -6)   
An38....I was in the exact same position. I was given the news about the prostate cancer while being biopsied for skin cancer. Ended up having the prostate surgery followed by surgery for the skin cancer. They were able to save my finger, however it doesn't look very pretty. Squamous cell isn't something you want to mess with.
You are beating back cancer, so hold your head up with dignity
 
Les
 
Age 58 at Diagnosis
Oct 2006 - PSA 2.6 - DRE Normal
May 2008 - PSA 4.6 - DRE Normal / TRUS normal
July 2008 - Biopsy 4 of 12 Positive 5 - 30% Involved Bilateral w/PNI - Gleason (3+3)6 Stage T1C
Robotic Surgery Sept 18, 2008
Pathology October 1, 2008 - Gleason 7 (3+4) Staged pT2c NO MX - Gland 50 cc
Seminal Vesicles and Lymph Nodes clear
Positive Margins Right Posterior Lobe
PSA 5 week Oct 2008 <.05
                   3 month Jan 2009     .06
                   6 month Apr 2009     .06
                   9 month Jul  2009     .08
                 12 month Oct 2009     .09 
                 18 month April 2010   .19

Sonny3
Veteran Member


Date Joined Aug 2009
Total Posts : 2447
   Posted 8/6/2010 8:04 AM (GMT -6)   
An,

I feel for you and your situation. We have not communicated directly and you may not have seen many of my posts in the past. But I can understand where you are coming from.

My wife and I both are dealing with cancer. She for 5 years and me for 1+. It is tough, it does overwhelm and it can make you feel very helpless.

But it is a new world for you. Sadly, one that you have very little experience with on a personal level this close. It takes a great leap of faith to believe that you guys are not the first, nor will you be the last.

Take solace to a degree from all of the brothers and sisters here at HW and know that we have all been where you are at some point in our lives. Yet we are still here. We have our ups and downs and we rejoice in our successes and gain support from our collective strength when we have set-backs.

You have found a place to share and we are linked now for the rest of our lives.

Call on us anytime. We are here for each other. We know from experience that tomorrow will bring joy and comfort in some form or another and to some degree, be it small to tremendous.

As difficult as it may be today, have faith, have trust, and enjoy the love you and your husband share, to the fullest each and every day. I know that is what makes it bearable for my wife and I and many of the couples here.

Sonny
60 years old when diagnosed
PSA 11/07 3.0
PSA 5/09 6.4
da Vinci 9/17/09
Post Surgery Pathology: GS 4+3=7
Stage: T3a
Tumor Volume 12.5%
positive margin, extra-prostatic extension
30 day PSA 0.4, 50 day psa 0.53, 64 day psa 0.6
IMRT completed 1/15/10 35 treatments- 70Gy

2/24/10 FIRST POST RAD PSA 1.0---CARRRP --waiting for the next test.
3/22/10 Second Post RAD PSA 1.5 Dammmmnnn stubborn son of a gun
4/19/10 YAHOO PSA dropped to 1.2 Moving in the right direction.
5/7/10 PSA test 1.3 Sodium Fluoride PET Scan & CT SCAN -performed
5/20/10 PSA test 1.2 Holding off on future tests for 3 months- single lytic lesion found and scheduling radiation.
7/22/10 PSA test 1.3 - Begin radiation for MET on leg

An38
Veteran Member


Date Joined Mar 2010
Total Posts : 1148
   Posted 8/6/2010 8:17 AM (GMT -6)   
Les, thank you. If you can get through this, so can we.

Sephie, I know I should wait for the path report but its three whole days before I have a chance of getting it. My husband has a full body check every year, all have been good so far, with the last being in January but this cancer was not picked up. In late March there was a kind of scratch between his first two knuckles which bled. Then it crusted over and my husband was obsessively picking at it so it didn't heal. Mysister who is a doctor was visiting from the US in late May, looked at it and said that it looked like a wart but she didn't like the look of it and it should be excised out. So it was - this all happed really quickly - and unfortunately at the GP and not at a specialist.

Once I get that path report the next step will be to get to a dermatologist. If the margins are not clear he will need some surgery I think. And if so we have to figure out what takes higher priority the PC surgery or the skin cancer.

Bob we are far from giving up but for today, for half an hour it was more than I could handle.

An
Husband's age: 52. We live in Sydney Australia.

In 2007 my husbands PSA level was 2.5.
In Feb 2008 it was 1.7
In Oct 2009 it was 3.67 with a free PSA ratio of 27
In Feb 2010 it was 4.03 with a free PSA ratio of 31.
In June 2010 it was 2.69

DRE normal.
Biopsy 28/4/2010: results, negative for a diagnosis of PC however 3 focal ASAPs on left side of prostate at base, apex and at transition resulting in the conclusion "...small acinar proliferation is suspicious but not diagnostic for prostatic adenocarcinoma."
Review of biopsy by experienced pathologist, results,
1 out of 12 core diagnosed with 10% of Gleason score 3+3 cancer (left transitional)
1 out of 12 cores with ASAP (left apex), suspicious but not diagnostic of cancer

Next steps: Nerve sparing RP on 20th August 2010.

My husband's maternal grandfather died of prostate cancer at 72. His maternal uncle died of prostate cancer at 60. Because he is the third generation to be diagnosed he has hereditary PC.

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 8/6/2010 8:46 AM (GMT -6)   
An,

So very sorry and heartbroken for the both of you. It is a terrible blow to deal with both at the same time. I will make no excuses for doctors and medical staff that communicate poorly. Don't let that turn your off of doctors in general. There probably isn't any connection between the skin and prostate cancers, so its not apples to apples. You will just have to deal with this one step at a time, and not let it overwhelm you. Your emotional outbreak would be clearly understood and felt by any person here, male or female. We share your fears, your anquish, and your pain.

Please stay in steady touch, the entire HW gang, myself included, is behind you and your dear husband.

We love our brother/sister Oz folks that are among us.

David in S.C.
Age: 58, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, next one: Aug 3
Latest:  7/9 cath #6 - 41 days, 8/9 2nd corr surgery, 8/9 cath #7 - 38 days, mapped  9/9, 10/1 - 3rd corr. surgery - SP cath, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12 ,Cath #11 - 21 days,  Cath #12 - 41 days, 3/2- Corr Surgery #5, Cath #13 - 4 days, Cath #14- 27 days, Cath #15 - 26 days, Cath #16 - 31 days, Cath #17 - 39 days, 7/2 - Corr Surgery #6, Cath #18 - 13 days, Cath #19 - 17 days, Total Blockage, Cath # 20 - 7/19

don826
Veteran Member


Date Joined May 2008
Total Posts : 1010
   Posted 8/6/2010 9:18 AM (GMT -6)   
An,

Sorry to hear about your husband. There is a drug in phase II trials and is available for "compassionate use" here in the states. According to the news reports it is effective in about 40% of the cases. I mentioned it to my dermatologist yesterday and he was aware of the drug. But he did say that it only lasts for about 20 months. This was not said in the news reports. I think the drug(s) are the following. There was a peculiar side effect in that the drug turned the patient's hair white but the good news was that if this happened it was indicative of success with the drug.

Bristol-Myers Squibb's ipilimumab and Pfizer's tremelimumab

Best to you and hubbie.
Don
Diagnosed 04/10/08 Age 58 at the time
Gleason 4 + 3
DRE palpable tumor on left side
100% of 12 cores positive for PCa range 35% to 85%
Bone scan clear and chest x ray clear
CT scan shows potential lymph node involvement in pelvic region
Started Casodex on May 2 and stopped on June 1, 2008
Two years on Lupron completed 01/2010.
Started IMRT/IGRT on July 10, 2008. 45 treatments scheduled
First 25 were full pelvic for a total dose of 45 Gray to lymph nodes.
Last 20 to prostate only. Total dose to prostate 81 Gray.
Completed IMRT/IGRT 09/11/08.
PSA 02/08 21.5 at diagnosis
PSA 07/08 .82 after 8 wks of hormones
PSA 10/08 .642 one month after completion of IMRT, 6 months hormone
PSA 03/09 .38 six months post radiation and nine months into hormones
PSA 06/09 .36 or .30 depending on who did the test
PSA 09/09 .33 one year after IMRT and 16 months into hormone
PSA 03/10 .32 18 months after IMRT Still on hormones
PSA 05/10 .42 Rising a little as the lupron wears off. Last lupron shot 01/10.
PSA 06/10 .322 Maybe the .42 reported in May was in error?
PSA 07/14/2010 0.1

LV-TX
Veteran Member


Date Joined Jul 2008
Total Posts : 966
   Posted 8/6/2010 9:28 AM (GMT -6)   
An38 The aproach of wait and see on the return of the skin cancer was the same protocol my dermatologist used. Unfortunately we stayed on that same protocol for several years, taking a little off each time it came back. I finally went to a center of excellance and was immediately scheduled for MOH's surgery. This is where they cut and sample, cut and sample until you have clean margins. Then follow up with plastic surgery. In the scheme of things, this procedure is actually much easier to deal with than the PCa surgery was.

Best of luck to you.
You are beating back cancer, so hold your head up with dignity
 
Les
 
Age 58 at Diagnosis
Oct 2006 - PSA 2.6 - DRE Normal
May 2008 - PSA 4.6 - DRE Normal / TRUS normal
July 2008 - Biopsy 4 of 12 Positive 5 - 30% Involved Bilateral w/PNI - Gleason (3+3)6 Stage T1C
Robotic Surgery Sept 18, 2008
Pathology October 1, 2008 - Gleason 7 (3+4) Staged pT2c NO MX - Gland 50 cc
Seminal Vesicles and Lymph Nodes clear
Positive Margins Right Posterior Lobe
PSA 5 week Oct 2008 <.05
                   3 month Jan 2009     .06
                   6 month Apr 2009     .06
                   9 month Jul  2009     .08
                 12 month Oct 2009     .09 
                 18 month April 2010   .19

Cajun Jeff
Veteran Member


Date Joined Mar 2009
Total Posts : 4106
   Posted 8/6/2010 9:47 AM (GMT -6)   
An. Thanks for letting us know. I know at times times like this things tend to look very dark but know that we are all here with you trying to shine some light for you.

Please do keep us posted.

Cajun jeff
9/08 PSA 5.4 referred to Urologist
9/08 Biopsy: GS 3+4=7 1 positive core in 12 1 pre cancer core
10/08 Nerve-Sparing open radical
Surgery Path Report Downgrade 3+3=6 GS Stage pT2c margins clear

3 month: PSA <0.1
6 month: PSA <0.1
10 month:PSA <0.1
1 year: PSA <0.1
16 month:PSA <0.1

ED - Started Cialis at 3 months, tried all 3, 6 months added pump, 9 months Tried MUSE (YUCK) Bad experience.
1 year mark Found new Urologist visit was at 14th month post surgery
Started Injections, Caverject! (Success)
17 month: ED making improvements : Oral Meds gets me 85%

Tudpock18
Forum Moderator


Date Joined Sep 2008
Total Posts : 4156
   Posted 8/6/2010 9:51 AM (GMT -6)   

Hi An:

Sorry for your angst and the performance of the doctors doesn't help!  In any case, I'll share some thoughts on your issues.  First of all, and coincidentally, I just had a basal cell skin cancer removed yesterday.  It was found during a routine dermatology visit two weeks ago...body inspection, found something peculiar, cut it off for biopsy and called two days later telling me basal cell skin cancer.  The protocol here then is to come in for out patient surgery where they cut a little deeper to make sure they get the margins.  It was no big deal, took about 1/2 hour...now I have 10 stitches and am moving on with life. 

There is a high probability that there is NO connection between your husband's PCA and his skin cancer.  I have the fair Northern European skin also and (probably like your husband) got way too much sun as a kid.  That is a sure recipe for skin cancer but, fortunately, it is usually no big deal.  Hopefully his pathology will come back as basal cell but as long as it's not melanoma or some strange variety you shouldn't be too worried.

As far as the question as to which to take care of first, I think it depends on what your dermatogist says about the pathology.  If it's basal cell then he probably has had it for some time and a few more months probably won't matter, i.e. take care of the PCa first.  However, if you get a feel that the skin cancer is somewhat aggressive then I suggest you get that handled first.  As we have discussed before, you husband's PCA stats suggest slow growing (if not indolent) cancer so a short delay in treating the PCa is not likely to hurt.  I guess the thing I don't suggest is taking care of both cancers at the same time.  From what I know about what CAN happen post surgery for PCa I think you want to be focused totally on that recovery for a few months.

In any case, I'll pray that the skin cancer is a mild sort and I wish you the best.

Tudpock (Jim)

 


Age 62, Gleason 3 + 4 = 7, T1C, PSA 4.2, 2 of 16 cores cancerous, 27cc
Brachytherapy December 9, 2008.  73 Iodine-125 seeds.  Procedure went great, catheter out before I went home, only minor discomfort.  Regular activities resumed, everything continues to function normally as of 4/10/10.  6 month PSA 1.4 and now 1 year PSA at 1.0.  My docs are "delighted"!

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 8/6/2010 10:04 AM (GMT -6)   
In NY the waiting time for a dermatologist to perform MOHs is at least 3 months. They are booking late October appointments now.
I am not sure what kind of wait you have in your part of the world, but it might be a good idea to schedule something now. That way if hubby needs some work done 3 months from now, you will already be on the schedule. If everything looks OK you can always cancel the appointment a week before.
Jeff

rhb47
Regular Member


Date Joined Mar 2010
Total Posts : 208
   Posted 8/6/2010 12:43 PM (GMT -6)   
Hi An,

Nothing to add to all the excellent posts above-just wanted to let you know that I am thinking about you and your husband.

Renee
Husband diagnosed 3/10
Age 56, PSA 4.7, free 7.6%
Biopsy 5 of 10 cores positve-all right side-25% to 57%
Gleason 6
DaVinci surgery with Dr. Vip Patel scheduled 8/9/10
 

Ed C. (Old67)
Veteran Member


Date Joined Jan 2009
Total Posts : 2458
   Posted 8/6/2010 2:03 PM (GMT -6)   
An,
Sorry about the bad news of having to deal with 2 types of cancer. I know all about the sun exposure in Australia being really bad. I hope his skin cancer pathology report will show negative margins. I wish you both the best.
Age: 67 at Dx on 12/30/08
PSA 9/05 1.15; 8/06 1.45; 12/07 2.41; 8/08 3.9; 11/08 3.5 free PSA 11%
2 cores out of 12 were positive Gleason (4+4) and (4+5)
Negative CT scan and bone scan done on 1/16
Robotic surgery performed 2/9/09 Dr Fagin, Austin TX
Prostate weighed 57 grams size:5.2 x 5.0 x 4.9 cm
Posterior lateral lesions measuring 1.5 x 1.4 x 1.0 cm showing focal capsular penetration over a distance of 3mm in circumference.
Prostatic adenocarciroma accounts for approx. 10-20% of the hemisphere.
Gleason 4+4
both nerve bundles removed,
pT3a Nx Mx, Negative margins
seminal vesicles clean, lymph nodes: not dissected
continent after 5 months
2 months PSA test 4/7/09 result <0.1
5 months PSA test 7/9/09 result <0.1
8 months PSA test 10/9/09 result <0.1
11 months PSA test 1/21/10 result 0.004
14 months PSA test 4/19/10 result 0.005

60Michael
Veteran Member


Date Joined Jan 2009
Total Posts : 2222
   Posted 8/6/2010 2:42 PM (GMT -6)   
An,
Sorry to hear that news as well. Hard not to fret when you just have the word "cancer" and no other info. I'd be finding a new set of Doctors. Please keep us posted and lets hope for the best.
Michael
Dx with PCA 12/08 2 out of 12 cores positive 4.5 psa
59 yo when diagnosed, 61 yo 2010
Robotic surgery 5/09 Atlanta, Ga
Catheter out after 10 days
Gleason upgraded to 3+5, volume less than 10%
2 pads per day, 1 depends but getting better,
 started ED tx 7/17, slow go
Post op dx of neuropathy
T2C left lateral and left posterior margins involved
3 months psa.01, 6 month psa.4, 6 1/2 month psa.5 on 11/28/10
Starting IMRT on 1/18/10, Completed 39 tx at 70 gys on 3/12/10
6 week Post IMRT PSA .44 a drop from .5 but maybe more
Great family and friends
Michael

mikey1955
Veteran Member


Date Joined Dec 2008
Total Posts : 673
   Posted 8/6/2010 3:01 PM (GMT -6)   
An,

Sorry to hear your husband is dealing with both.

I had a skin cancer, too. I had a chunk of squamous cell carcinoma taken out of my leg about 10 years ago. about the size of the end of one of my fingers. Pathology said it was contained. I remember asking my GP if that cancer would increase my chances of another one. He said no, yet here I am. I can't say they were related.

Good luck and best wishes.

Mike
-Nov/Dec 07, March 08 and Dec 08: Severe perineum pain . Septra/Bactrim for 8 months for diagnosed prostatitis.
-PSA start of 2008: 5.3..... PSA June of 2008: 7.3
-14 DRE all benign or nothing felt
-TRUS Biopsy Nov 08: 5 of 8 cores positive GS 3+3 or 6. 30-65%. Perineural invasion.
-General Health: pretty good, 5' 10", 180 lbs, slim.
-Open RP surgery: May 09 both nerve bundles spared. Bilateral lymph node dissection performed. Discharged 48 hours after surgery.
-Post Surgery Pathology: pT3a N0 MX, extraprostatic extension (EPE), stage III prostate cancer, lymph nodes clear, seminal vesicles clear, Gleason upraded to 3+4 GS 7. EPE within surgical margins. Other than prostate and EPE, all tissue removed negative for cancer involvement.
-Bladder control within 48 hours of catheter removal
-ED ongoing but improving. ED oral meds didn't do much initially. TRIMIX was working very well. Initial dose of 0.1 mL too much. Had priapism at 0.075 mL that ended up in a humiliating ER visit. Doses recently after 50% dilution by Uro about 0.025 mL or less. Don't use Trimix anymore...I'm too sensitive to it, even at very low doses and the Alprostadil is pretty consistent in causing erection pain...had a few episodes of 3+ hour wood with pain.
-Levitra now starting to work at low doses of 5 mG to 10 mG. Sometimes the side effects like stuffy nose aren't fun...sometimes OK.
-Was supposed to see ED doc last week, but due to his schedule, will now be late August. Will discuss bimix with him.
 

Fairwind
Veteran Member


Date Joined Jul 2010
Total Posts : 3744
   Posted 8/6/2010 3:21 PM (GMT -6)   
Melanoma is a big deal, yours does not sound like melanoma..The other types of skin cancer are very curable with proper treatment.. Good Luck and Fair Winds..

Post Edited (Fairwind) : 8/6/2010 3:27:56 PM (GMT-6)


Mimi723
Regular Member


Date Joined Jul 2010
Total Posts : 38
   Posted 8/6/2010 5:51 PM (GMT -6)   
I am so very sorry, An. I will keep you in my thoughts.

In the course of all the tests, we found my husband had a lung aneurysm and some other lung issues. The doctor thinks they are granulomas.

One day at a time.

Mimi
Husband, 62
Gleason 6
Surgery set for Aug. 16

deer hunter
Regular Member


Date Joined Jan 2010
Total Posts : 246
   Posted 8/6/2010 6:17 PM (GMT -6)   
An these are hard words to hear when your already dealing with one C word already . but cancer puts a hold on everything else, especial when it's someone we love. my husband was dx 2006 PC since then it seems like the whole world  has been turned up side down.and there's nothing we can do about it except be there for them and love them and listen to them.so I wish bothof you the best and I will keep ya'll in our prayers .Today we celebrated our 44 wedding anniversary.
dx age 57 01/06 open RP 4/06 psa in 01/06 8.1  surgery path report Gleason 3+4=7 poorly differentiated  tumor was 90%involved in both lobes surgical margins postive. in the right apex and right radial margins tumor grade G3  perineural invasion present high grade of PIN found  T2c NX MX PSA 0706  .01 10/06 .02 01/07 .03 04/07 .04  06/07 .05  07/07 .08 07/07 bone scans pelvic ct neg. 08/07 proscintic scan neg.9/07 psa.10 net with rad onc. wanted to do SRT but i did not do it 10/07  saw a new dr at Emory University [my old dr urg. suggested second opinion ]  bone scans negs ct scans pelvics neg. biopies of the bladder and adrinal glands neg.another proscintic scan neg.12/07 Psa .11 clinial trial Emory injected with protons to try and find the cancer cells no luck 3/08 psa .17 06/08 psa .23 psa 09/08 psa .32 12/08 psa .39 3/09 psa .39 6/09 psa .43  meet with medical onc. he said  i might have waited to long to start SRT 7/09 psa .50  another bone scan ct scan all neg.MRI neg. meet rad. psa the last of 7/09was .55 onc. 7/09 started casdex 50mg 1 day for 30 days 2 shots of lupron started rad treament 10/09 40 treatments 75 gm 12 shots each time all aroud pelvic finished 12/09  psa .07 and psa 01/10.05 next dr visit 03/10 wait and see 3/10 psa.05 5/14/10  family doc done blood work at my request her lab psa .01  
6/17/10 saw rad.onc. having problems with hips and muscles {bone density test sch, 6/25/10 wait and see

An38
Veteran Member


Date Joined Mar 2010
Total Posts : 1148
   Posted 8/6/2010 8:47 PM (GMT -6)   
Thank you everyone for so much concern and empathy. And for making me realise that so many of us are dealing with more than one medical issue at a time.

Yesterday was terible but today is another day. We managed to get our hands on that pathology report today and speak to another GP about it.
Yes it is squamous cell carcinoma (not melanoma thank goodness). But sqamous cell is much more serious than basel.
The good news is that the margins are clear but the bad news is that the margin is only 0.3mm at the deepest point. The GP says that that's the minimum margin recommended for squamous cell.

My husband pointed out two small leisons that have been around for a while (!) and one looks like another squamous cell whereas the other looks like a basel. They have to come out - we have an appointment for Monday. Only problem now is my husband who wants to fit in two games of golf before the PC surgery and since the suspected squamous cell is on his hand he thinks the stitches may ruin his swing or stop him playing. I do not understand his thought process at the moment, he really needs to sort out his priorities but I am leaving him alone to think about it.

Thanks again everyone.

An
Husband's age: 52. We live in Sydney Australia.

In 2007 my husbands PSA level was 2.5.
In Feb 2008 it was 1.7
In Oct 2009 it was 3.67 with a free PSA ratio of 27
In Feb 2010 it was 4.03 with a free PSA ratio of 31.
In June 2010 it was 2.69

DRE normal.
Biopsy 28/4/2010: results, negative for a diagnosis of PC however 3 focal ASAPs on left side of prostate at base, apex and at transition resulting in the conclusion "...small acinar proliferation is suspicious but not diagnostic for prostatic adenocarcinoma."
Review of biopsy by experienced pathologist, results,
1 out of 12 core diagnosed with 10% of Gleason score 3+3 cancer (left transitional)
1 out of 12 cores with ASAP (left apex), suspicious but not diagnostic of cancer

Next steps: Nerve sparing RP on 20th August 2010.

My husband's maternal grandfather died of prostate cancer at 72. His maternal uncle died of prostate cancer at 60. Because he is the third generation to be diagnosed he has hereditary PC.

Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 8/6/2010 9:58 PM (GMT -6)   
Hi An,
That's a good report considering. Ugh!

Now that my testosterone levels are getting back to normal, I kinda understand your husbands thinking about the golf. When I was on HT I thought I had permanently lost my desire to forego asking for directions or talking with the guys at the water cooler. Shoe shopping was far more appealing than golf. But now, I'm back to being unreasonable and have renewed my subscription to water cooler talk...:-)

All my very best to you and your husband while you step from stone to stone. The good news is that both of these cancers are beatable. Patience and the wonderful wife he has will help a great deal.

Peace to you both...

Tony
Disease:
Advanced Prostate Cancer at age 44 (I am 48 now)
pT3b,N0,Mx (original PSA was 19.8) EPE, PM, SVI. Gleason 4+3=7

Treatments:
RALP ~ 2/17/2007 at the City of Hope near Los Angeles.
Adjuvant Radiation Therapy ~ IMRT Completed 8/07
Adjuvant Hormone Therapy ~ 28 months on Casodex and Lupron.

Status:
"I beat up this disease and took its lunch money! I am in remission."
I am currently not being treated, but I do have regular oncology visits.
I am the president of an UsTOO chapter in Las Vegas

Blog : www.caringbridge.org/visit/tonycrispino

Aimzee
Veteran Member


Date Joined May 2010
Total Posts : 1404
   Posted 8/7/2010 2:24 AM (GMT -6)   
An38 said...
Thank you everyone for so much concern and empathy. And for making me realise that so many of us are dealing with more than one medical issue at a time.

Yesterday was terible but today is another day. We managed to get our hands on that pathology report today and speak to another GP about it.
Yes it is squamous cell carcinoma (not melanoma thank goodness). But sqamous cell is much more serious than basel.
The good news is that the margins are clear but the bad news is that the margin is only 0.3mm at the deepest point. The GP says that that's the minimum margin recommended for squamous cell.

My husband pointed out two small leisons that have been around for a while (!) and one looks like another squamous cell whereas the other looks like a basel. They have to come out - we have an appointment for Monday. Only problem now is my husband who wants to fit in two games of golf before the PC surgery and since the suspected squamous cell is on his hand he thinks the stitches may ruin his swing or stop him playing. I do not understand his thought process at the moment, he really needs to sort out his priorities but I am leaving him alone to think about it.

Thanks again everyone.

An
 
An, I am so sorry you are dealing with this unexpected news!  I am so happy you did obtain the pathology report giving you a few extra days to take necessary steps in dealing with this matter.  I know how stressful this can be.  I feel the dermatologist may provide additional insight.  May God provide the wisdom to take the necessary steps towards complete recovery.  Is there a MRI or ultrasound that needs to be done?
 
I know at times it is difficult to understand the thought processes of our men!  The thing with golf is similiar to Ron and his fishing.  I knew he needed to get away, even for a short time.  Men often use sports to unwind.  Perhaps advice from the doctor may help your husband with this decision?  I think you are handling the matter properly!  I am praying for you both!
 
Sonny, your message was so warm and loving.  It brought tears to my eyes.  Thank you!
 
Aimzee

Husband Ron, age 63
Had Progesterone shots for 6 months.  January PSA was .05. 
4/1/10 PSA 5.5  Prostate size = 50 cc.
On Cipro (antibiotic) for 16 days
Bone Scan/CT Negative
Biopsy 4/20/10  12 samples... Adenocarcinoma:  3 positive on right side,
one core left base (5% ` 0.5 mm) -  two cores of left lateral mid
(20% ~ 2mm, 10%, 10% ~ 1mm) - No Perineural Invasion
Gleason 6 (3+3)
The surgery has been postponed twice.
August 18, 2010 - da Vinci Prostatectomy
 
(I do the posting for both of us.)

Sephie
Veteran Member


Date Joined Jun 2008
Total Posts : 1804
   Posted 8/7/2010 5:00 AM (GMT -6)   
An, glad you have the path report in hand and that your husband's skin cancer is not melanoma. As you already stated, squamous cell is more serious than basal cell but is still highly treatable and curable. I can't imagine how stressful this all is for you but please be assured that you and hubby are in the hearts and minds of many of us here at HW.

When I hear stories like yours, a quote from Mother Teresa comes to mind: Lord, I know you never give me more than I can handle but sometimes I wish you didn't have so much confidence in me.

Men think differently than women - you know the old Men Are From Mars, Women Are From Venus. I imagine that the only thing you can do is give him the space he needs to sort this all out - as frustrating as it may be for you.
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (solitary focus of extraprostatic extension). Perineural tumor infiltration present. Apex margin, bladder neck and SVs negative. Final Gleason 3+4. PSA: 0.0 til July 2009. August 2009 - 0.1, September 0.3, October back to 0.0, December 0.0, March 2010 0.0. Next PSA in 6 months. Thank you God!

Sleepless09
Veteran Member


Date Joined Jul 2009
Total Posts : 1267
   Posted 8/7/2010 8:32 AM (GMT -6)   
An, I have followed this thread with concern for you and your husband and I jump in now for two reasons. One is to wish you both all possible success. While he is dealing with two cancers it seems from the pathology reports that you can have some reasonable hope of a cure for each --- and, isn't cure the "C" word we cancer patients love to hear!

The second reason is your husband's golf. I don't think it's a Mars and Venus thing. I think it is a human response to major stress to revert, often in ways that seem to others unreasonable, to some icon of normality and hold to it fiercely. We have a very close friend (we have celebrated New Year's together for more than 50 years, I'm "Uncle" to her kids and she's "Aunt" to mine) who is in the midst of her second round of chemo after her ovarian cancer returned 12 months after surgery. She knows, we all know, her life is in peril and the chemo is not so much about cure as stalling. One of the things that sustains her is keeping her life as normal as possible. Doing exactly what she's always done, and sometimes, such as when it comes to planting out the spring flowers at her cottage, it is only accomplished because of a bloody minded determination that to those of us wanting to help, or say, "let the gardner do it this year, for Heavens sake!" unreasonable. But, for her, it is a way of being in control and fighting the cancer by doing what she'd be doing if she didn't have cancer.

An, I suggest that your husband's single minded need to play golf has little, or nothing, to do with playing golf and everything to do with making a statement to himself, and to the cancer, that he's in control of his life and will NOT let the cancer dictate to him!

I'll be watching with interest for more news and be assured you'll both be in my prayers on the 20th.

Sheldon AKA Sleepless
Age 67 in Apil '09 at news of 4 of 12 cores positive T2B and Gleason 3 + 3 and 5% to 25% PSA 1.5
Re-read of slides in June said Gleason 3 + 4 same four cores 5% to 15%
June 29 daVinci prostatectomy, Dr. Eric Estey, at Royal Alexandra Hospital Edmonton one night stay
From "knock out" to wake up in recovery less than two hours.  Actual surgery 70 minutes
Flew home to Winnipeg on July 3 after 5 nights in Ramada Inn  ---  perfect recovery spot!
Catheter out July 9
Final pathology is 3 + 4 Gleason 7, clear margins, clear nodes, T2C, sugeron says report is "excellent"
 
Oct 1st 09 -- dry at night, during day some stress issues.
Oct 31st padless 24/7 
 
First post op PSA Sept 09  less than 0.02
PSA on Oct 23, 2009 less than 0.02
PSA on Jan 8, 2010  less than 0.02
PSA on April 9, 2010 less than 0.02 
PSA on July 9, 2010 (one year) less than 0.02
  

An38
Veteran Member


Date Joined Mar 2010
Total Posts : 1148
   Posted 8/7/2010 7:23 PM (GMT -6)   
Thank you Sleepless, Aimzee and Tony for your recent comments.

Unfortunately I have done some research on husbands situation and the research isn't good. The minimum recommended margin of healthy tissue for Squamous cell carcinoma (SCC) is 4mm.(Again the second GP is wrong!!) My husband has 0.3mm. This is why the hand is a terrible place to get SCC as it has little removable flesh and is prone to recurrence and metasteses. See text below copied from an article on the internet. My husband's SCC was in the interdigital cleft (the area in between the knuckles).

"Haws et al2 reported a 0.1% to 3% rate of metastasis for squamous cell carcinoma of sun-exposed skin. However, squamous cell carcinoma of the hand is associated with a higher risk of metastasis compared to squamous cell carcinoma of the skin in other regions of the body, having been reported to metastasize in 5.5% to 28% of cases.

In 1981, Rayner described the “danger zone” of the hand to include the dorsal skin of the proximal phalanges, interdigital clefts, and the first webspace. He noted that tumors in this region of the hand were associated with an increased incidence of local recurrence and metastasis when compared to other regions of the hand. The 5-year survival rate for metastatic squamous cell carcinoma is 20% to 40%."

So the question really is whether this situation overrides the RP situation in terms of needing to get fixed and in that case perhaps we will need to move the surgery dates.

I feel helpless and overwhelmed. Any ideas on what we should do next are appreciated.

An
Husband's age: 52. We live in Sydney Australia.

In 2007 my husbands PSA level was 2.5.
In Feb 2008 it was 1.7
In Oct 2009 it was 3.67 with a free PSA ratio of 27
In Feb 2010 it was 4.03 with a free PSA ratio of 31.
In June 2010 it was 2.69

DRE normal.
Biopsy 28/4/2010: results, negative for a diagnosis of PC however 3 focal ASAPs on left side of prostate at base, apex and at transition resulting in the conclusion "...small acinar proliferation is suspicious but not diagnostic for prostatic adenocarcinoma."
Review of biopsy by experienced pathologist, results,
1 out of 12 core diagnosed with 10% of Gleason score 3+3 cancer (left transitional)
1 out of 12 cores with ASAP (left apex), suspicious but not diagnostic of cancer

Next steps: Nerve sparing RP on 20th August 2010.

My husband's maternal grandfather died of prostate cancer at 72. His maternal uncle died of prostate cancer at 60. Because he is the third generation to be diagnosed he has hereditary PC.

Post Edited (An38) : 8/7/2010 7:26:26 PM (GMT-6)

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