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Regular Member

Date Joined May 2009
Total Posts : 85
   Posted 8/19/2010 12:03 PM (GMT -6)   
Hi: Just wondering if anyone can give us some tips that have worked for them. My husband has mets in his right femor. He will be getting chemo. in the future, but still working on trying to supress the testosterone. So theymay up his casodex (he is also on lupron) will see what happens in the next month. Right now he is dealing with throbbing pain in his leg, not sure if it is the mets or if it is muscle problems as he has had knee issues etc. with his legs for years. The doctor prescribed him a pain killer, but wondered if anyone else out there has any other things they have done besides the pain killers. Would appreciate anyones help.
AGe 54 diagnosed March of 2007
PSA 107

Gleason 8

Stage T2 or T3 (weren't sure was out of prostate capsule)

Bone scan march 2007 and Aug 2008 both clear

ct 2007 clear

started casadex/lupron March of 2007 (casadex only for 4 months)(lupron for 2 yrs)

Aug 2007 had 37 treatments (also radiated lymph nodes)

psa spr 07-107,went down to .34 by Dec 08, March 09 0.7, May 1.54,
Added casodex, PSA Aug 1.19, Psa Dec 09 5.65
Going for Bone scan and Ct Scan, than decide what to do with rising psa
Bone scan Dec 09 and follow up May 2010- met on right femor
Psa continue to rise, continue on Lupron and casodex

Veteran Member

Date Joined Nov 2009
Total Posts : 1100
   Posted 8/19/2010 1:43 PM (GMT -6)   
You might want to ask a radiation oncologist about spot radiation -- they can direct radiation at the met, which can be effective in reducing/eliminating pain. They can also use radiopharmaceuticals, though my understanding is that spot radiation is typically preferred when the mets are localized. Best wishes, Medved.
Age 46.  Father died of p ca. 
My psa starting age 40: 1.4, 1.3, 1.43, 1.74, 1.7, 1.5, 1.5

Veteran Member

Date Joined Aug 2009
Total Posts : 2448
   Posted 8/19/2010 2:10 PM (GMT -6)   

Just last week I finished my radiation treatment for a MET that was found on the my femoral head at the hip joint. When it was first found I had not yet begun to experience pain, but by the time we started radiation I was beginning to know that it was there.

My Radiation Oncologist explained that in addition to ridding me of the pain for the met, it was important to radiate it now before it expanded. The femur is a major weight bearing bone in the body and as mets expand they tend to weaken the bone. He wanted to take car of it before my leg broke just walking down the street.

My personal experience with this would say talk to a Radiation Oncologist, talk about where the met is located and talk about radiation as opposed to masking the problem with drugs.

Just for what it's worth,

60 years old when diagnosed
PSA 11/07 3.0
PSA 5/09 6.4
da Vinci 9/17/09
Post Surgery Pathology: GS 4+3=7
Stage: T3a
Tumor Volume 12.5%
positive margin, extra-prostatic extension
30 day PSA 0.4, 50 day psa 0.53, 64 day psa 0.6
IMRT completed 1/15/10 35 treatments- 70Gy

2/24/10 FIRST POST RAD PSA 1.0---CARRRP --waiting for the next test.
3/22/10 Second Post RAD PSA 1.5 Dammmmnnn stubborn son of a gun
4/19/10 YAHOO PSA dropped to 1.2 Moving in the right direction.
5/7/10 PSA test 1.3 Sodium Fluoride PET Scan & CT SCAN -performed
5/20/10 PSA test 1.2 Holding off on future tests for 3 months- single lytic lesion found and scheduling radiation.
7/22/10 PSA test 1.3 - Begin radiation for MET on leg
8/9/10 - Met radiation completed

Veteran Member

Date Joined Dec 2008
Total Posts : 3149
   Posted 8/19/2010 2:44 PM (GMT -6)   
Not that this will help you, unless you find their trials, but a new pain control for mets is in the making and may make it to market. Metastron is the name of it you can read about it.
Spot radiations are useful in mets, maybe some drug therapies as guys already mentioned.

METASTRON is the name of this.
Dx-2002 total urinary blockage, bPsa 46.6 12/12 biopsies all loaded 75-95% vol.; Gleasons scores 7,8,9's (2-sets), gland size 35 normal, ct and bone scans appearing clear- ADT3 5 months prior to radiations neutron/photon 2-machines, cont'd. ADT3, quit after 2 yrs. switched to DES 1-mg, off for 1 yr., controlled so well, resumed, using intermittently, pleased with results

Regular Member

Date Joined May 2009
Total Posts : 85
   Posted 8/19/2010 3:07 PM (GMT -6)   
Thanks for the information. We knew about spot radiation, but we're not sure if it is a result of the mets or of just muscle issues. With radiation it can only be done once so would want to make sure that is what is causing the problem. Will be seeing our oncologist soon so will discuss that with him. Just wondered if maybe someone out there had some alternative to medication.
AGe 54 diagnosed March of 2007
PSA 107
Gleason 8
2007Radiation and hormone therapy 2007 to present
Apr 2010 bone scan positive for mets in right femor
Aug 2010 stay on lupron, possibly add casodex as testosterone level is a little high
Chemo in the future and waiting to see if accepted on trail for drug to add to chemo

Elite Member

Date Joined Oct 2008
Total Posts : 25393
   Posted 8/19/2010 5:25 PM (GMT -6)   
Spot Radiation would be the normal approach at this point, usually works well for most patients.
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 ?
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, on Catheter #21, will be having Ileal Conduit Surgery in Sept.
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