I'm concerned PSA .01 jumped to .02 in 4 months

New Topic Post Reply Printable Version
32 posts in this thread.
Viewing Page :
 1  2 
[ << Previous Thread | Next Thread >> ]

hangin-in
Regular Member


Date Joined Sep 2008
Total Posts : 78
   Posted 8/20/2010 11:39 AM (GMT -6)   
I reached my two-year RP anniversary. My PSA tests over these two years have been pretty consistent - every three months 0.01.
 
I just got the results of my last test this morning and it came up to 0.02. I know this is low and still considered undetectable but I am concerned.
 
Could this be the beginning of a trend? I'm getting worried. What do you think?
Thanks for all your help.
Hangin

PSA 12/06=1.6 12/07=2.1 5/08=2.6
Biopsy 6/4/08 12 core 4 Pos 15%,15%,8%,3%
Diagnose@Age 51 Gleason 3+3=6 Bone & Cat Normal
Lapro Surgery 8/18/08 at MSK
T2c organ confined pos apical margin GL 3+3 = 6 (tert 4)
Catheter removed 8/26-reinserted 8/29-removed 9/2
No cont/ED problems from get-go.
Post op PSA
10/08 < .05
12/08 <.05
12/08 <.05
6/09 0.01
9/09 0.01
12/09 0.01
4/10 0.02

hangin-in
Regular Member


Date Joined Sep 2008
Total Posts : 78
   Posted 8/20/2010 11:51 AM (GMT -6)   
I had to correct my signature, sorry.
4/10 0.01
8/10 0.02

PSA 12/06=1.6 12/07=2.1 5/08=2.6
Biopsy 6/4/08 12 core 4 Pos 15%,15%,8%,3%
Diagnose@Age 51 Gleason 3+3=6 Bone & Cat Normal
Lapro Surgery 8/18/08 at MSK
T2c organ confined pos apical margin GL 3+3 = 6 (tert 4)
Catheter removed 9/2
No cont/ED problems from get-go.
Post op PSA
10/08 < .05
12/08 <.05
12/08 <.05
6/09 0.01
9/09 0.01
12/09 0.01
4/10 0.01
8/16/10 0.02

Post Edited (hangin-in) : 8/20/2010 12:08:16 PM (GMT-6)


Magaboo
Veteran Member


Date Joined Oct 2006
Total Posts : 1210
   Posted 8/20/2010 12:23 PM (GMT -6)   
Hangin, with such good pathologist numbers and such good post RRP PSA test results, I don't believe that you have anything to worry about at this time. I think you can just relax and enjoy life. The next few PSA test will tell you more, but this small increase in PSA is most likely just a lab error or a slight blip in your PSA.
All the best to you.
 
Mag.

Born Sept 1936
PSA 7.9
-ve DRE
Gleason's Score 3+4=7, 2 of 8 positive
open RP 28 Nov 06 (nerve sparing), Post op staging T3a
Gleasons still 3+4=7
Seminal vesicles and lymph nodes clear
Catheter out 15 Dec 06, Dry since 11 Feb 07
All PSA tests in 2007 (4) <.04
PSA tests in 2008: Mar.=.04; Jun.=.05; Sept.=.08; 3 days before Rad Start=0.1
Salvage RT completed (33 days - 66 Grays) on the 19th Dec., 08.
PSA in Jan., 09=0.05; July 09 <0.04; JAN 10 <0.04; Jul 10 <.04

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 8/20/2010 12:42 PM (GMT -6)   
How consistent were you? Diet, activity, time of day? Depending upon the equipment used, the tolerance can be +/- 0.02. So, you are well within the noise limit.

That said, every recurrence started exactly the same way. Take a few more measurements then decide if it is a trend. Watch it like a hawk and you'll get it early.
Jeff

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7201
   Posted 8/20/2010 4:17 PM (GMT -6)   
I can't answer you as I have the same concerns/fears.
 
See my sig
 
Mel
PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (PSAf: 24%), PCA3 =75 .
Biopsy 11/30/09. Gleason 4+3. Stage: T1C. Current Age: 64
Surgery: Dr. Menon @Ford Hospital, 1/26/10.
Pathology Report: G 4+3. Nodes: Clear. PNI: yes. SVI: No. EPE: yes. Pos. Margin: Yes-- focal-- 1 spot .5mm. 100% continent by 3/10. ED- in progress. First post-op PSA on 3/10/10-: 0.01. PSA on 6/21/10--0.02. Next PSA late Sept.

ChrisR
Veteran Member


Date Joined Apr 2008
Total Posts : 825
   Posted 8/20/2010 5:14 PM (GMT -6)   
It has been proven time and time again here that fluctuations in PSA at the ultra sensitive level are absolutely meaningless. Many people here have had the ultra sensitive test go up and down all over the place. Stop torturing yourself and move to the standard test. Even Johns Hopkins doesn't use it.
Dx 42
Gleason 6 (tertiary score 0)
OPEN RP 10/08  Johns Hopkins
pT2 Organ confined Gleason 6
PSA Undetectable as of 10/15/09
Next PSA 10/15/2010

BillyMac
Veteran Member


Date Joined Feb 2008
Total Posts : 1858
   Posted 8/20/2010 5:51 PM (GMT -6)   
I agree with the other posters although my personal preference is for ultrasensive testing. But if you registered 0.014 (rounded to nearest 2 decimal place and reported as 0.01) and the next test registered 0.016 (again rounded to the nearest 2 decimal place and reported as 0.02) it shows how illusory changes at this level can be. And this is without taking a 20% margin for error into account. Great result so take it easy and relax. Using ultrasensitive it is important to watch for a trend before starting to worry, rather than minor variations. A trend at this level may show 0.01 then 0.02 then 0.04 then 0.06 etc. The constant increase with time could indicate a relapse up to 2 years earlier than the standard test.
Bill
Biopsy

4 of 10 cores positive for Adenocarcinoma-------bummer!
Core 1 <5%, core 2----50%, core 3----60%, core 4----50%
Biopsy Pathologist's comment:
Gleason 4+3=7 (80% grade 4) Stage T2c
Neither extracapsular nor perineural invasion is identified
CT scan and Bone scan show no evidence of metastases
Da Vinci RP Aug 10th 2007

Post-op

Positive for perineural invasion and 1 small focal extension
Negative at surgical margins, negative node and negative vesicle involvement
Some 4+4=8 identified ........upgraded to Gleason 8
PSA Oct '07 <0.1 undetectable
PSA Jan '08 <0.1 undetectable
PSA April '08 <0.001 undetectable (disregarded due to lab "misreporting")
PSA August '08 <0.001 undetectable (disregarded due to lab "misreporting"-----it is not possible for any lab to get a reading of less than .003)

Post-op pathology rechecked by new lab:

Gleason downgraded to 4+3=7
Focal extension comprised of grade 3 cells
PSA September '08 <0.01 (new lab)
PSA February 09 <0.01
PSA May '10 <0.01

www.yananow.net/Mentors/BillM2.htm

Never underestimate old people ............ you don't get to be old by being stupid.

Post Edited (BillyBeans) : 8/20/2010 5:54:33 PM (GMT-6)


hangin-in
Regular Member


Date Joined Sep 2008
Total Posts : 78
   Posted 8/21/2010 7:39 PM (GMT -6)   
Thanks so much for your responses. I feel calmer now.
PSA 12/06=1.6 12/07=2.1 5/08=2.6
Biopsy 6/4/08 12 core 4 Pos 15%,15%,8%,3%
Diagnose@Age 51 Gleason 3+3=6 Bone & Cat Normal
Lapro Surgery 8/18/08 at MSK
T2c organ confined pos apical margin GL 3+3 = 6 (tert 4)
Catheter removed 9/2
No cont/ED problems from get-go.
Post op PSA
10/08 < .05
12/08 <.05
12/08 <.05
6/09 0.01
9/09 0.01
12/09 0.01
4/10 0.01
8/16/10 0.02

goodlife
Veteran Member


Date Joined May 2009
Total Posts : 2691
   Posted 8/21/2010 8:28 PM (GMT -6)   
Chris R,

I'm not sure that your statements are exactly accurate. Ultrsensitive PSA is a fairly exacting science, under some fairly rigid standards. I think it is we who cause variations, not the lab or labs. Worried Guy is on the money. Testing same time of day, same dietary routine, same lab, etc. I have been reading these posts for quite a while and I have not seen wild flucuations of ultrasensitive PSA testing.

That being said, certainly a fluctation of .01 is possible at that level based on multiple reasons. I would say that relaxing for another 3 months, (I know how hard it is), is the best advice anyone can give.

Until you see a flucuation of .1, then enjoy your stay in the zero club.
Goodlife
 
Age 58, PSA 4.47 Biopsy - 2/12 cores , Gleason 4 + 5 = 9
Da Vinci, Cleveland Clinic  4/14/09   Nerves spared, but carved up a little.
0/23 lymph nodes involved  pT3a NO MX
Catheter and 2 stints in ureters for 2 weeks .
Neg Margins, bladder neck negative
Living the Good Life, cancer free  6 week PSA  <.03
3 month PSA <.01 (different lab)
5 month PSA <.03 (undetectable)
6 Month PSA <.01
1 pad a day, no progress on ED.  Trimix injection
No pads, 1/1/10,  9 month PSA < .01
1 year psa (364 days) .01
15 month PSA <.01

ChrisR
Veteran Member


Date Joined Apr 2008
Total Posts : 825
   Posted 8/22/2010 6:21 AM (GMT -6)   
Goodlife,

There is absolutely 0 benefit to the ultra sensitive test. Nobody will touch you with any kind of secondary treatment until your PSA is .1 or greater. It fact biochemical recurrence is technically not until .2 anyway. You are just torturing yourself finding fluctuation below .1.

You also need to go back and look at the posts closer, there are a bunch of people using the ultra sensitive test showing fluctuations. Look up a guy called "diagnosed41". He story is a classic example.

Also, show me the data where people using the ultra sensitive test who went on to have secondary treatment that fared better then those using the standard test. If that were true every uro would require the ultra sensitive test.

You are causing yourself unnecessary pain.
Dx 42
Gleason 6 (tertiary score 0)
OPEN RP 10/08  Johns Hopkins
pT2 Organ confined Gleason 6
PSA Undetectable as of 10/15/09
Next PSA 10/15/2010

Dave7
Regular Member


Date Joined Jul 2006
Total Posts : 202
   Posted 8/22/2010 7:31 AM (GMT -6)   

Thanks for the thread.  My last PSA jumped from .01 to .03, so I'm a bit anxious about the next one.  Is this a trend or a blip?  Certainly could be the start of a trend.

I understand about the anxiety caused by testing below .1, but I don't want to be in the dark leading up to a possible .1

Dave


Age:54
PSA 5/22/06: 5.6
DaVinci surgery: 9/14/06
Gleason: 3+3
Organ confined, clean margins.
Both nerve bundles spared.

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 8/22/2010 8:13 AM (GMT -6)   
Chris,
I'm with Goodlife.
I will continue to have mine checked to 2 decimals and will watch it like a hawk. If my 6 month PSA moves from 0.01 to 0.03 to 0.05 I will be on it so fast it will make my bladder spin.
I want the plan in place and the treatment ready if it rises above my set threshold.
I person receiving a one decimal result will never know until it flips from .1 to .2 and then, maybe, the doc would insist on another 3 month wait to make sure it was not a fluke. That can be 2 years after it has started to rise.
I liken the high resolution test to the advent of digital watches. Before we had them, a minute a day was considered ok. It did not make a difference in the long run. The meeting started anyway, you got to dinner on time. With digital watches now we expect them to be accurate to 1 second a month. It doesn't make a difference except when you are turning on the TV and want to see the first few seconds or are trying to catch the right train in Japan. Given that the mechanical and digital watches are the same price and durability which do you select? It is clear the industry has gone digital.

It is far better for us to have the information and use it wisely rather than not get it because someone else thinks it might confuse us or make us worry. Pushing the example further, why ask for the results at all? Let's have it sent directly to our Uros and PCPs and have them call us if they think we need to do something. That way we won't have to "worry our heads about something we don't know anything about". There is not a guy here who would accept that.
My heat breaks for vam4710 in this thread: Dad's PCa is back
The guy trusted his doc who clearly just put the results in the file without alerting him. Look at his stats. It will make your stomach turn.
I want all the ammunition I can get so that will not happen to me. I'll take 3 decimals if they give it.

Jeff (<0.01ng/ml by Roche Cobas 601 ECLIA)

BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 8/22/2010 8:47 AM (GMT -6)   
I agree with the value of the ultra sensitive PSA. My PSA went from .07 to .28 within 3 months and them to .5 two months later. If I had been using the normal test, I wuld have not been able to plan for secondary treatment until my PSA was almost .3 and movng very quickly.
Dx with PC Dec 2008 at 56, PSA 3.4


Biopsy: T1c, Geason 7 (3+4) - 8 cores taken with 4 positive for PCa, 30% of all 4 cores.

Robotic Surgery March 2009 Hartford Hospital, Dr Wagner
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes negitive - tumor volume 9%
nerves spared, no negitive side effects of surgery

One night in hospital, back to work in 3 weeks

psa Jun 09 <.01
psa Oct 09 <.01
psa Jan 10 .07 re-test one week later .05
psa Mar 10 .28 re-test two weeks later .31
psa May 10 .50

April 10 MRI and Bone Scan show lesion on lower spine, false positive.

Started HT 5/25/10 with 3 month shot of Trelstar. SRT scheduled for late July

psa July 10 <.01 HT at work

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 8/22/2010 8:53 AM (GMT -6)   
ChrisR - what you said isn't entirely correct. You said that you wouldn't have biochemical recurranc until a PSA of .2

Many doctors now, consider 3 consecutive rises above .1 as recurrance, that is the standard used in my area. The radiation oncologists locally I spoke with want to see salvage radiation begun before you hit .2. That is their normal "line in the sand". My own uro told me just this week, that .05 is considered the legitimate prescence of PSA after surgery as a primary treatment or radiation as a secondary treatment.

David in SC
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 ?
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, on Catheter #21, will be having Ileal Conduit Surgery in Sept.

ChrisR
Veteran Member


Date Joined Apr 2008
Total Posts : 825
   Posted 8/22/2010 9:29 AM (GMT -6)   
You guys are confusing accuracy of the test with frequency of testing. Accuracy does not detect a rise in PSA sooner. Frequency of testing does.
Dx 42
Gleason 6 (tertiary score 0)
OPEN RP 10/08  Johns Hopkins
pT2 Organ confined Gleason 6
PSA Undetectable as of 10/15/09
Next PSA 10/15/2010

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 8/22/2010 10:47 AM (GMT -6)   
Chris,
It is combination of both accuracy and frequency. Most of us here are on a 3 month or 6 month testing schedule. Some are even annual. That decimal point can help me see a trend in values a year or more before my PSA reaches 0.14 - which, by the way, would theoretically still be reading 0.1 . I'll take any advantage I can.

Here's how I use the data:

I am at <0.01 now. If it moves to 0.01 I will consider myself on "storm watch" status: I'm not worried but I will make sure I don't skip the next reading. If it goes to 0.02 I am on "storm warning" status: I might ask the Uro to change my schedule back to 3 months from 6 months. ) And if it goes to 0.05 I am on "storm alert" and will be on the phone with every doc who touched my case. I am a pT3a, (with a pre-RP PSA of 23.
I am not going to wait for it to rise to .2 before starting treatment. I'm making plans at 0.05 so by the time I actually get an appointment I am still, hopefully, well below 0.08.

Despite what the Rolling Stones said: Time is not always on our side.

Jeff (<0.01ng/ml by Roche Cobas 601 ECLIA)

I am not expecting disaster but I do like the idea of having a plan in place, just in case. It is like keeping water and food in the basement and 20 gallons of gasoline and a generator in the barn - cheap insurance. The extra digit costs nothing - just an upgrade from the 2002 machine to a 2006 model.

Post Edited (Worried Guy) : 8/22/2010 10:54:26 AM (GMT-6)


daveshan
Regular Member


Date Joined Jan 2010
Total Posts : 363
   Posted 8/22/2010 11:10 AM (GMT -6)   
Chris beg to differ, I'm on a 3 month cycle, my lab reports <0.04 and both my uro and rad oncologist agree we will hit it at 0.05. Actually the rad' guy wants to zap me now but that's another story.

If my PSA goes from undetectable to detectable with no normal prostate tissue left in me that's enough for me, I'm hitting it with everything I can. There is no way in heck I'm waiting for 0.2.
Diagnosed 12-09 age 55
07-06 PSA 2.5
01-08 PSA 5.5 (PCP did not tell me of increase or schedule follow-up!!!!)
09-09 PSA 6.5 Sent for consult with Urologist
11-09 Consult, scheduled for biopsy, found out about PSA from '08 (yes I was pissed)
12-09 Biopsy, initial Gleason 9 (4+5) later reduced to 8 with tertiary 5, ain't much but I'll take it.
01-10 Bone Scan, "appears negative"
03-01-10 RRP in Durango CO by Dr Sejal Quale and Dr Shandra Wilson, no naked eye evidence of spread, Vesicles and lymph nodes taken for microscopic exam.

03-16-10 Removal of cath' and pathology results of samples.
Multifocal carcinoma with areas of Gleason pattern 3, 4 and 5, Overall Gleason grade 4+4 with tertiary 5, Bilateral involving 21% of left lobe, 3% of right lobe, Invasion of left Seminal vesicle, Tumor focally present at left resection margin, 9 lymph nodes removed all negative, Tumor staging pT3b NO MX

04-23-10 PSA <0.04....... 06-07-10 PSA <0.04..... 08-03-10 <0.04
05-03-10 1 week without pads
06-28-10 ;-)

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 8/22/2010 12:18 PM (GMT -6)   
Hey daveshan,
We are together brother. If I get to 0.05 I'm hitting it with both barrels ASAP. There is no honor in fighting a prolonged asymmetric war.

Try to find out what machine they are using for the analysis. I am part of a study comparing the "older" readings, 2006, to the new technology, 2010.
Check out my stats below for the comparison. For me, a 0.04 and 0.03 old, is <0.01 new.
Jeff

4/14 9 months - 0.04 (Siemens Centaur) and <0.01 (Roche ECLIA).
7/12 1 year - 0.03 (Siemens Centaur, direct chemilum); <0.01 (Roche Cobas 601 ECLIA)

Post Edited (Worried Guy) : 8/22/2010 12:22:18 PM (GMT-6)


ChrisR
Veteran Member


Date Joined Apr 2008
Total Posts : 825
   Posted 8/22/2010 1:15 PM (GMT -6)   
Again, show me the data where ultra sensitive PSA saves lives.

Daveshan, you had a positive margin.

Worried Guy your signature shows your ultra sensitive tests all over the place. No wonder you are worried.

To each his own. To me it's a waste.
Dx 42
Gleason 6 (tertiary score 0)
OPEN RP 10/08  Johns Hopkins
pT2 Organ confined Gleason 6
PSA Undetectable as of 10/15/09
Next PSA 10/15/2010

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 8/22/2010 2:18 PM (GMT -6)   
Chris,
My numbers are not all over the place. They are very stable.
They were always 0.04 or 0.03 with the older 2006 standard and always <0.01 with the new 2010 standard.

Eventually the new one will be the only numbers reported. But for now, both standards are supplied so we can maintain a point of reference. This is part of a huge correlation study now underway.

I'll bet you a couple of bucks that within 2 years, your numbers will likewise be reported via the ECLIA to 2 decimal points.

Time and technology march on.

Jeff (actually a lot less worried with a <0.01 than I would be with a <0.1 )

BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 8/22/2010 2:34 PM (GMT -6)   
We all need to manage these desease based upon our own situation. If I was a G6 with negitive margins and an undetectable PSA for 2+ years I would be happy with a normal PSA test every 6-12 months. But as a G8 with the possibility of recurrence at about 35-40% I am going to watch my PSA like a hawk, ultra sensitive every 3 months. It doesn't matter to me that it hasn't been proven to save lives. I am only worried about one. mine. I would want to be able to react as quickly as possible.
Dx with PC Dec 2008 at 56, PSA 3.4


Biopsy: T1c, Geason 7 (3+4) - 8 cores taken with 4 positive for PCa, 30% of all 4 cores.

Robotic Surgery March 2009 Hartford Hospital, Dr Wagner
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes negitive - tumor volume 9%
nerves spared, no negitive side effects of surgery

One night in hospital, back to work in 3 weeks

psa Jun 09 <.01
psa Oct 09 <.01
psa Jan 10 .07 re-test one week later .05
psa Mar 10 .28 re-test two weeks later .31
psa May 10 .50

April 10 MRI and Bone Scan show lesion on lower spine, false positive.

Started HT 5/25/10 with 3 month shot of Trelstar. SRT scheduled for late July

psa July 10 <.01 HT at work

Sephie
Veteran Member


Date Joined Jun 2008
Total Posts : 1804
   Posted 8/22/2010 2:40 PM (GMT -6)   
Listen guys...everyone is going to make their own decision about when - and if - to begin a secondary line of treatment. I am concerned though about anyone jumping the gun too soon with RT. Look at my John's interesting little blip last summer/fall: He was less than 0.1 for 17 months, then his August 2009 test showed 0.1, followed with a 0.3 in September 2009. We met with a radiation oncologist, had CT scan and bone scan, and were all ready to begin RT in October. John's third - and supposedly definitive PSA test - was scheduled for mid October and we were all set to begin RT within a couple of days of that test. Lo and behold, his October PSA reading came back at undetectable and has continued to stay there since then. I often wonder what would have happened if we jumped the gun when it hit 0.3 since we were told by some people not to even bother with the 3rd PSA test. I was ready at PSA test #2 but John and his urologist said "no, we wait for the 3rd blood test." The 'what ifs" make me wince when I think of how close we had come to exposing John to somewhere around 66 gys of radiation when it wasn't necessary.

While John's surgical stats may not indicate as aggressive a disease as others here had, he was a T3a with extraprostectic extension. In his case, the urologist/surgeon said that it was likely benign prostate tissue around the nerve bundles (which were spared) that caused the blip.

I only tell our story to illustrate to those new here how important it is to first verify that there is an upward trend in PSA before pushing the button. Again, each person can and should make their own decision about what steps, if any, to take next, and this decision should be made based on their own history in consult with their medical team.
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (solitary focus of extraprostatic extension). Perineural tumor infiltration present. Apex margin, bladder neck and SVs negative. Final Gleason 3+4. PSA: 0.0 til July 2009. August 2009 - 0.1, September 0.3, October back to 0.0, December 0.0, March 2010 0.0. Next PSA in 6 months. Thank you God!

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 8/22/2010 3:02 PM (GMT -6)   
Sephie,
You bring up a good point. I am not sure if I asked this already but how consistent were you two during the testing? same lab? same time of day? meals? sex?
Jeff

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7201
   Posted 8/22/2010 3:24 PM (GMT -6)   
Jeff:
 
You know, Jeff, you keep mentioning the importance of being consistent when getting PSA tests. That sounds so logical, but I'm not sure that it carries any validity.
 
Are there any studies that supports such a contention regarding POST-OP PSA tests?
 
I know one time I had a probable UTI and my team at Ford Hospital all said it didn't matter in terms of influencing my PSA.
 
Mel
PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (PSAf: 24%), PCA3 =75 .
Biopsy 11/30/09. Gleason 4+3. Stage: T1C. Current Age: 64
Surgery: Dr. Menon @Ford Hospital, 1/26/10.
Pathology Report: G 4+3. Nodes: Clear. PNI: yes. SVI: No. EPE: yes. Pos. Margin: Yes-- focal-- 1 spot .5mm. 100% continent by 3/10. ED- in progress. First post-op PSA on 3/10/10-: 0.01. PSA on 6/21/10--0.02. Next PSA late Sept.

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 8/22/2010 4:29 PM (GMT -6)   
Mel,
There is ample evidence discussing the effect of sex and DRE on PSA pre RP. We also know that nerve bundles produce some as well. So I figure it does not hurt to be as consistent as possible. It can't hurt and can only help. I am not going to test the theory unless I can be a part of a free research study.
I can hear the discussion now: "Hon, we have to do it tonight. We wouldn't want to invalidate the study would we? "
Jeff
New Topic Post Reply Printable Version
32 posts in this thread.
Viewing Page :
 1  2 
Forum Information
Currently it is Sunday, June 17, 2018 10:20 PM (GMT -6)
There are a total of 2,972,679 posts in 326,005 threads.
View Active Threads


Who's Online
This forum has 160834 registered members. Please welcome our newest member, Christina1984.
360 Guest(s), 3 Registered Member(s) are currently online.  Details
dinkydonuts, Coral, Tall Allen