PSA test result mid-way thru SRT - Wow!

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Im_Patient
Veteran Member


Date Joined Aug 2009
Total Posts : 665
   Posted 9/14/2010 3:17 PM (GMT -6)   
Although my rad oncologist did not need me to get a PSA test until 3 months after SRT was complete, my uro surgeon wanted me to keep getting monthly PSA tests for now. My Sept 8 test result, which was at 5 weeks thru SRT, was 0.17, down from 0.41 the month before. I just called to confirm that this was not an error.

I was prepared to wait many months to see a drop, and had been warned it could be 3-6 months before I would see one. Has anyone else seen a drop this early on? I am trying to figure out whether the PSA fell for unknown reasons, or whether the radiation can actually be blamed for the drop.

Now I ain't complaining... in fact, I'll take it! yeah
Jeff
Gleason, 3+4; PSA, 7.9
Robotic Prostatectomy, March 2008 (Age 48 then), nerves both sides spared, post surgery analysis confirmed 3+4 Gleason,
pT2c, prostate 60.2g, margins: negative; perineural invasion: present; lymphatic invasion: present; 3 lymph nodes removed, clear; seminal vesicle invasion: absent; Gleason 4 comprises 5-10% of carcinoma
PSA consistently <0.1 since surgery until Oct 09: 0.1; retested Oct 09, <0.1,
Jan 10, 0.2
retest Feb 1 confirmed 0.2
CT scan, bone scan Feb 10 both clear
PSA after, 2010: March, 0.17; April, 0.17; May, 0.24; June, 0.31; July, 0.29; Aug, 0.41
Started salvage IGRT on August 4, plan 72Gy total, 40 doses

Jakester
Regular Member


Date Joined Aug 2009
Total Posts : 285
   Posted 9/14/2010 3:35 PM (GMT -6)   
Mine did the opposite, it was up by mid-SRT but has started going down after finish (but no cigar yet). The rad oncologist said it was 50:50 odds in the middle and a great sign if down but didn't mean it wouldn't go down.

So a hardy congrats! This looks real good!

Enjoy!
Diagnosed 8/2008 Pre-op psa 4.2, Age 60 at dx
7 of 12 biopsies positive 3+3
DaVinci LRP 11/08
Post Op clear margins, no extraprostatic extension, vascular or perineural. Gleason 3+4=7, 5-10% of 4.
3 month psa .1 2/09, 6 month .1 5/09, 9 month .2 8/09
broke ankle bones 6/09
9/21/09 Bone scan clear, psa still .2
11/12/09 chest xray was clear, psa however up to .3,
01/05/10 psa still .3, SRT 01/19/10 started 39 sessions 70.2gy, psa 6 weeks into salvage IMRT up to .4
Post SRT psa at 10 weeks (5/31/2010) down to .2, @20 weeks (8/20/10) .1 (getting close)

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 9/14/2010 5:21 PM (GMT -6)   
jeff, glad you are ,about half done. never heard of testing in the middle of srt, i find that strange
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 ?
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, on Catheter #21, will be having Ileal Conduit Surgery in Sept.

Magaboo
Veteran Member


Date Joined Oct 2006
Total Posts : 1210
   Posted 9/14/2010 5:43 PM (GMT -6)   
Hi Jeff. Great to see the PSA go down, whatever the reason. I, like David, have not heard about testing during the period of SRT treatment. However, I was tested about 5 weeks after the completion of my SRT and everyone was happy to see that my PSA had dropped by 50%. Lets hope that your trend will continue and that by the time you're finished with your SRT the PSA will have retreated into the undetectable range.
All the best to you.
 
Mag

Born 1936
PSA 7.9, Gleason Score 3+4=7, 2 of 8 positive
open RP Nov 06, T3a, Gleasons 3+4=7, Seminal vesicles and lymph nodes clear
Catheter out 15 Dec 06, Dry since 11 Feb 07
All PSA tests in 2007 (4) <.04
PSA tests in 2008: Mar.=.04; Jun.=.05; Sept.=.08; 3 days before Rad Start=0.1, Salvage RT completed (33 days-66Gy) 19 Dec 08
PSA: in Jan 09 =.05, all tests to date (Jul 10) <.04
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