Pathology Report: tumor length/core sample length = %tumor

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Regular Member

Date Joined Feb 2010
Total Posts : 242
   Posted 9/17/2010 3:02 PM (GMT -6)   
The recent thread about the significance of the percentage of PCa noted in the pathology report got me to pull out my own report. What I found was that the percentage of PCa corresponded to the length of the tumor in relation to the length of the core sampled, i.e. tumor length/core sample length = % tumor. For example, in one of the samples, which was a 4+4=8 from the right apex, the core length was 13mm, the tumor length was 6.0mm, and the % tumor was given as 46%.

Is this the typical way used in the diagnosis to determine the % of tumor? I am assuming that it probably is but don't remember seeing it mentioned anywhere.

And if it is typical, does this tell us anything about the position of the tumor in relation to the margain.

Age 66, PC diagnosed 7/2009 at age 65
Stage: T2c, Gleason: 9 (4 + 5), 6 of 6 cores positive
Bone, CAT and MIR scans negative

Treatment: brachytherapy (103 palladium), 100 gy, 11/2010 + hormone therapy (Lupron + Casodex) + IMRT on Novalis, 45 gy, 3/2010.

PSA: 7/2009, At time of diagnosis -- 11.9
10/2009 -- 5.0
12/2009 -- 0.56
5/2010 -- 0.15
8/9/2010 -- 0.06

John T
Veteran Member

Date Joined Nov 2008
Total Posts : 4268
   Posted 9/17/2010 3:12 PM (GMT -6)   
San Carlos,
The PCRI web site has a section PC tools that has a tumor volume calculator. You have to input each core with it gleason and % and the spreadsheet will give an extimation of tumor volume. Only a scan like color doppler or MRIS can give you a good indiation of tumor position and relation to the margin.
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