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mr bill
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Date Joined Sep 2010
Total Posts : 688
   Posted 10/1/2010 8:18 AM (GMT -6)   
Have a question:
Three weeks post robotic and had PSA done at Clinic. Turns out it was .06.  anybody have any input?
 
 
Age 66
BPH since 2000. at least three negative biopsies Erie. Uro did not prescribe finasteride
2007 acute urine retention photoselective vaporize Clev. Clinic
8-9-10 Aug PSA rose to 10.14 with finasteride positive biopsy Cleveland gleason 9, cat & bone scan negative
9-8-10 Robotic prostatectomy at Cleveland. B iopsy 9 nodes, 2 positive,seminal & vas deferens positive invasive adenocarc

An38
Veteran Member


Date Joined Mar 2010
Total Posts : 1148
   Posted 10/1/2010 8:32 AM (GMT -6)   
The half life of PSA is 2-3 days. That means it halves every 3 days or so after a RP. Since you started at about 10, it would have been 5 after three days, 2.5 after 6, 1.25 after 9, 0.6 after 12, 0.3 after 15, 0.15 after 18, 0.075 after 21.

So I would say that you are right on track.

An

mr bill
Veteran Member


Date Joined Sep 2010
Total Posts : 688
   Posted 10/1/2010 8:40 AM (GMT -6)   
That is somethingI did not know and goes a long way in relieving someof my anxiety before I can get in to surgeon, about 2 hr drive, this afternoon. I just do not understand why he wanted to do a PSA only three weeks after surgery.
Age 66
BPH since 2000. at least three negative biopsies Erie. Uro did not prescribe finasteride
2007 acute urine retention photoselective vaporize Clev. Clinic
8-9-10 Aug PSA rose to 10.14 with finasteride positive biopsy Cleveland gleason 9, cat & bone scan negative
9-8-10 Robotic prostatectomy at Cleveland. B iopsy 9 nodes, 2 positive,seminal & vas deferens positive invasive adenocarc

142
Forum Moderator


Date Joined Jan 2010
Total Posts : 6949
   Posted 10/1/2010 9:03 AM (GMT -6)   
My uro/surgeon waits 8 weeks before doing the first post-op PSA.
He did mine at 7, just because of long holiday weekends, and warned me that it might be too soon.
They also only do 1 decimal precision, so my <0.1 undetectable was the best possible result (they do not do ultra sensitive to avoid anxiety). I had a more sensitive test done on my own about 6 months later.
 
So, as I see it, .06 at 3 weeks out is great.

rob2
Veteran Member


Date Joined Apr 2008
Total Posts : 1131
   Posted 10/1/2010 9:31 AM (GMT -6)   
The first one I had was 1 month after surgery and have been told it is the 3 month PSA that counts.
 
Age 48 at diagnosis
occupation accountant
PSA increased from 2.6 to 3.5 in one year
biopsy march 2008 - cancer present gleason 7
Robotic Surgery May 9, 2008 - houston, tx
Pathology report -gleason 8, clear margins
22 month  PSA <.04
continent at 10 weeks (no pads!)
ED is still an issue

ChrisR
Veteran Member


Date Joined Apr 2008
Total Posts : 825
   Posted 10/1/2010 9:37 AM (GMT -6)   
I was told by johns Hopkins it can take up to 3 months to wash out. They don't do a PSA before then.
Dx 42
Gleason 6 (tertiary score 0)

open RP 10/08 Johns Hopkins

pT2 Organ confined Gleason 6

PSA
10/15/2009 <.1
10/15/2010 <0.03
10/15/2011 -

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 10/1/2010 11:54 AM (GMT -6)   
definitely wait till the 3 month reading before having a solid opinion
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 ?
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, on Catheter #21, will be having Ileal Conduit Surgery in Sept.

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7205
   Posted 10/1/2010 12:04 PM (GMT -6)   
dITTO with what others said. I think it was 7 weeks for me.
 
Mel
PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (PSAf: 24%), PCA3 =75 .
Biopsy 11/30/09. Gleason 4+3. Stage: T1C. Current Age: 64
Surgery: Dr. Menon @Ford Hospital, 1/26/10.
Pathology Report: G 4+3. Nodes: Clear. PNI: yes. SVI: No. EPE: yes. Pos. Margin: Yes-- focal-- 1 spot .5mm. 100% continent by 3/10. ED- in progress. First post-op PSA on 3/10/10-: 0.01. PSA on 6/21/10--0.02. 9/21/10--0.06

mr bill
Veteran Member


Date Joined Sep 2010
Total Posts : 688
   Posted 10/1/2010 5:58 PM (GMT -6)   
Just got home from clinic (long day). Uro surgeon said he was encouraged by PSA .06.  I guess the reason the others want you to wait is that the PSa 1/2 life, which I did not know until AN38 posted that info. So what we are saying that it will go lower between 3 1/2 weeks post surgery and 8 weeks?
Age 66
BPH since 2000. at least three negative biopsies Erie. Uro did not prescribe finasteride
2007 acute urine retention photoselective vaporize Clev. Clinic
8-9-10 Aug PSA rose to 10.14 with finasteride positive biopsy Cleveland gleason 9, cat & bone scan negative
9-8-10 Robotic prostatectomy at Cleveland. B iopsy 9 nodes, 2 positive,seminal & vas deferens positive invasive adenocarc

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7205
   Posted 10/1/2010 8:30 PM (GMT -6)   
Bill:
 
Hopefully yes but I still don't know why he ordered the PSA
 
Mel

Sephie
Veteran Member


Date Joined Jun 2008
Total Posts : 1804
   Posted 10/2/2010 5:50 AM (GMT -6)   
Bill, a PSA of 0.06 3 weeks after surgery is great news...by standard PSA assays, that's less than 0.1 which is generally considered undetectable. My husband's first PSA was done at about 7 weeks post op and it was 0.1 (he was 6.4 pre surgery) and the surgeon was very happy, telling me that the next test in 1 month would be 0.0 (which it was). As you've read here, it takes time for the PSA to flush out of your system. The fact that your first PSA so soon after surgery has a zero to the left and the right of the decimal is an excellent sign.

Congratulations on this good news.

tarhoosier
Regular Member


Date Joined Mar 2010
Total Posts : 487
   Posted 10/2/2010 7:38 AM (GMT -6)   
If I read your pathology correctly you have two positive nodes, SVI and who knows what else, psa over 10 with Proscar, and with a G9. I would say that a psa at a few weeks post surgery of 0.06 is fanTAStic. Wine, scotch, whatever is your celebration drink, now is a good time.

mr bill
Veteran Member


Date Joined Sep 2010
Total Posts : 688
   Posted 10/2/2010 9:01 AM (GMT -6)   
Thank you all for the encouragement and good news. We need that.
Age 66
BPH since 2000. at least three negative biopsies Erie. Uro did not prescribe finasteride
2007 acute urine retention photoselective vaporize Clev. Clinic
8-9-10 Aug PSA rose to 10.14 with finasteride positive biopsy Cleveland gleason 9, cat & bone scan negative
9-8-10 Robotic prostatectomy at Cleveland. B iopsy 9 nodes, 2 positive,seminal & vas deferens positive invasive adenocarc

Sleepless09
Veteran Member


Date Joined Jul 2009
Total Posts : 1267
   Posted 10/2/2010 6:34 PM (GMT -6)   
Good news mr bill and good news is GOOD NEWS!
Congratulations.
Sheldon AKA Sleepless
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