New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Tim G
Veteran Member

Date Joined Jul 2006
Total Posts : 2358
   Posted 10/1/2010 10:25 PM (GMT -6)   
There's a new PSA test that has been developed for post-prostate surgery patients.  The standard and high-sensitivity tests now available measure PSA in nanograms (billionths of a gram).  The new PSA test (see blurb below) measures PSA in picograms (trillionth of a gram).  My question is do we need a test that is super sensitive? The anxiety index for post-prostatectomy patients is high enough already without adding to it with a test that is this sensitive.  Does it make any difference if a PSA result is 1 trillionth of a gram vs. 2 trillionths of a gram?
MedWire (9/30, Guy) reported that scientists at the Boston-based Quanterix Corporation "have developed a novel method to detect serum prostate-specific antigen (PSA) levels in men who have undergone surgery for prostate cancer." In fact, "in preliminary validation studies, the AccuPSA test -- which uses Single Molecule Array technology to separate individual PSA molecules and count them -- showed a lower detection limit of 0.01 pg/ml, and a quantification limit of less than 0.05 pg/ml. The assay also demonstrated good agreement with a standard PSA test when used to detect higher PSA levels

Post Edited (TimG) : 10/1/2010 9:38:33 PM (GMT-6)

Veteran Member

Date Joined Jul 2010
Total Posts : 3887
   Posted 10/1/2010 10:39 PM (GMT -6)   
Many surgeons use the standard test that reads undetectable at 0.0 Why put patients through all the worry as the ultra-sensitive readings float around? In the end, will it make any difference??

Veteran Member

Date Joined Apr 2008
Total Posts : 831
   Posted 10/2/2010 8:17 AM (GMT -6)   
Like a lot of other junk we see. I doubt we will ever see anything about this again.
Dx 42
Gleason 6 (tertiary score 0)

open RP 10/08 Johns Hopkins

pT2 Organ confined Gleason 6

10/15/2009 <.1
10/15/2010 <0.03
10/15/2011 -

Regular Member

Date Joined Mar 2010
Total Posts : 145
   Posted 10/2/2010 8:48 AM (GMT -6)   
Actually for high grade Gleason patients, it may make a difference. Many high grade tumors produce very low PSA so a low PSA score in these individuals may not necessarily be indicative of what is actually going on. I can see a potential use for this.
Dx June 2007 - age 48

davinci RRP October 2007
75% of prostate involved
Positive margin
Scans clear
No detectable mets
SRT - Feb 2008
At Dx: 8
Mar 09: 0.4
Jun 09: 0.7
Aug 09: 1.7
Feb 10: .008
Apr 10: .007
Jul 10: .006
Sep 10: .005

Commenced Dr. Robt Leibowitz "Three Pronged Approach" protocol in August 2009

Completed chemo Dec 28 2009
New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, September 18, 2018 11:55 PM (GMT -6)
There are a total of 3,004,515 posts in 329,151 threads.
View Active Threads

Who's Online
This forum has 161742 registered members. Please welcome our newest member, Belcorgin.
288 Guest(s), 5 Registered Member(s) are currently online.  Details
OzLyme, dbrookenz, Girlie, Lightlife, noodlesnoodles