Trace amounts of PSA?

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BillyMac
Veteran Member


Date Joined Feb 2008
Total Posts : 1858
   Posted 10/8/2010 4:05 PM (GMT -6)   
Here is an interesting article that discusses the other sources of PSA in the male anatomy ......... sources that are intact after prostatectomy and vary from man to man. It would explain why even after a successful and curative prostatectomy PSA could still be detected.

www.andrologyjournal.org/cgi/rapidpdf/jandrol.107.002576v1.pdf?ck=nck

Bill

creed_three
Veteran Member


Date Joined Jan 2007
Total Posts : 762
   Posted 10/10/2010 3:52 AM (GMT -6)   
Hi Bill,
 
Thanks for posting this link. Just dropped in momentarily tonight, and opened the link and read it, and found it interesting. Several years ago when I consulted with another member about PSA readings here,  she mentioned these sorts of things (and the glands involved) that the article you provide also mentions. At the 3 year point we checked at last consult with doc,  why the fluctuations between 0.02 and 0.03 for my husband, and confirmed (in my hubby's case) that this was probably the situation with his readings that small amounts were secreted by this gland. This is sort of at odds in a way I know, with recent discussions here about rising ultrasensitive readings,  but this is a helpful resource for anyone wanting to read in more detail about other aspects as you say, in order to further inform their situation.  Anyway, I found it interesting as it confirmed what someone wise once mentioned previously to me here, but explores it in more detail etc. thanks again Bill. While we keep a very close eye on CJ's PSA readings we are happy with all at the moment,  and I always think of that Cowper gland or whatever it is called,  as being responsible for the current 0.03...anyway every little bit of info helps... cheers for now Bill Boy!      Lana    turn
Creed_three (Lana) - with husband "CJ" now aged 52.5 yrs (49 years at diagnosis).
PSA (2002) 2.1. (2006) 3.5.  1 x 5% core of 12 positive at biopsy. Open Radical Prostatectomy with nerve sparing April 2007 Sydney, Australia. Gleeson 3 + 4 = 7. 2 x small multifocal lesions. Contained. Undetectable <.1 PSA since: June 2007-0.01, Oct 2007-0.02, April 2008-0.02: Oct 2008-0.03, Nov, 2008-0.02, April 2009-0.03, April 2010 - 0.03. 

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 10/10/2010 9:28 AM (GMT -6)   
good luck lana and cj!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 ?
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, on Catheter #21, will be having Ileal Conduit Surgery in Sept.
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