Anyone Ever Heard of This Company?

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Regular Member

Date Joined Jan 2010
Total Posts : 91
   Posted 10/14/2010 8:05 PM (GMT -6)   
The name of the company is called Aureon. They have products that predict the aggressiveness of the disease. One is called "Prostate px" for predictions based on initial biopsy tissue and another called "Post-Op px" for predictions based on post op pathology tissue. You can Google them. Since many of us in this forum have experienced post surgical biochemical recurrence and are thus in a "gray" area about how to proceed with this disease, I thought it might at least be worth taking a look at this prediction tool. The company claims that the prediction tool is significantly more accurate than using statistics based on surgical margins or ECE alone. The reasoning is that this tool actually utilizes your own tissue samples and then chugs through some very complex fancy mathematical algorithms. The details are contained in a pamphlet on their website. The limitation in the prediction is that its accuracy is good out to 5 years post op (for the Post Op product). In my case, I'm slightly beyond 5 years post op, but in their conclusion they state:

When a patient experiences a biochemical
recurrence post surgery, Post-Op Px can provide the
physician and the patient with useful information
about the patients likelihood of serious disease

Just wondering if any of you have heard of this product and what your thoughts on it are.

As always, thanks for your helpful feedback.

Dx: in 6/2005 age 49, PSA 4.1, 2/10 cores pos, G6, T1c
bone scan: negative
daVinci RRP 8/2005, Hartford Hospital, Dr. Wagner
Post-surgery upgraded G7 (3+4), pT2c, NX,MX, neg. margins, perineural invasion present, tumor invades capsule wall, but not entirely through it.
PSA <0.1 until 4th yr post surgery, then 7/09 0.1, 10/09 0.2, 1/10 0.2, 2/10 0.14, 4/10 0.16,
8/10 0.25, 9/10 0.23

Regular Member

Date Joined Mar 2010
Total Posts : 208
   Posted 10/15/2010 8:21 AM (GMT -6)   

Yes, I've heard of this as my husband had it done. We have not received the results yet from his doctor and to tell the truth if we had it to do over I'm not sure we would have it done. Reason: cost-this test costs $3200.( list price ) and we're not sure our insurance will pay. If they don't, Aureon says they will work with you-reduced cost , I'm assuming as insurance would never pay this amount. My husband's surgeon believes in it and as my husband works for a research institute he is always interested in this sort of thing. We'll see...
Husband diagnosed 3/10
Age 56, PSA 4.7, free 7.6%

Biopsy 5 of 10 cores positve-all right side-25% to 57%
Gleason 6
DaVinci surgery with Dr. Vip Patel scheduled 8/9/10

Post Op: Gleason 3+4=7
Negative surgical margins and lymph nodes
No seminal vesicle and angiolymphaic invasion
perineural invasion present
Both nerve bundles spared
No ED or incontinence
6 wk. PSA .01

Regular Member

Date Joined Aug 2008
Total Posts : 328
   Posted 10/15/2010 11:39 AM (GMT -6)   
Havent heard of the company will ask my doc next visit in November. What has your doc said about your rising PSA, are you doing any additional treatment. Good Luck!!!
Causes me to have even more anxiety to see cases like yours that have similiar stats as me and 4 yrs ok, then bam!!!

Good Luck!!
Age Dx 37, 7/2008, First PSA : 4.17 5/2008
Second PSA After 2 weeks of antibiotics : 3.9 6/2008
DRE: Negative 5/2008, Biopsy: 6 out 12 Postive all on right side, Gleason 7 (3+4). Bone Scan/CAT Scan: Clear 7/2008
Cystoscope: Normal 7/2008, Prostate MRI: Normal 7/2008
Da Vinci Surgery 7/2008, PostOp: T2c (On Both sides), margins clear, seminal clear, nodes, clear. Gleason 6(3+3).
6 Post OP PSA's from 9/2008 to 6/2010: <0.1

Regular Member

Date Joined Jan 2010
Total Posts : 91
   Posted 10/16/2010 6:48 AM (GMT -6)   
Renee: thanks for your feedback. This does seem somewhat cost-prohibitive. I will first check to make sure my insurance would cover it, or least, part of it. My urologist seems to think pretty highly of the test. I also mentioned it to a rad oncologist yesterday during a consultation. He wrote it down in his notepad and said he was definitely going to look them up. Best of luck to you and your husband!

SHU93: My doc and I have been discussing my rising PSA for over a year now. Yes, the recurrence was a major bummer. However, it took a while for it to recur, it has not risen aggressively and I had negative surgical margins, so we don't know where the cancer is anyway. As mentioned above, I've spoken with a rad oncologist and even he said for a guy with my stats, it's a "crap shoot" (his words) as to whether I should pull the trigger on SRT. You're right about our similar stats, but, yours are actually more favorable. Your initial biopsy, graded G7 (3+4) was downgraded post-surgery to G6 (3+3), whereas my initial G6 (3+3) was upgraded post-surgery to G7 (3+4). Best of luck to you going forward!


Post Edited (TaurusBull) : 10/16/2010 5:17:59 PM (GMT-6)

New Member

Date Joined Oct 2010
Total Posts : 11
   Posted 10/17/2010 2:48 PM (GMT -6)   
Too late for me but keep us posted please.
Late 07 PSA UP/Early 08 First Biopsy - Neg
Late 08 PSA Higher/Early 09 Second Biopsy - Neg
Early 10 PSA UP/Early 10 Third Biopsy - Positive
26 Cores...4 positive
8/23/10 RP Gleason 6+ 5% of Prostate Cancerous Wide Margins
Nodes negative/Vesicles negative
Tumor contained in capsule
NO post surgery PSA test as of yet.
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