Pill versus Shot

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Veteran Member

Date Joined Dec 2009
Total Posts : 1268
   Posted 10/15/2010 6:39 AM (GMT -6)   
I'm at the point where a high dose of the pill is working well for ED; however, I do have some side effects (with all three brands!), that I don't like.  Side effects include sniffles and headaches ... once saw blue with Viagra.
Trimix injections work well and I really like them.  They are more spontanious (sp?), and no side effects ... and they last a very long time wink .
Does anyone know if there are benefits to switching to the pill versus staying with the Trimix injections? 
I would still plan on taking low dose pills nightly (5 days per week) for penile rehab.
PSA 2007 - 2.8; 11/24/2008 - 7.6; PCa Dx 2/11/09; age at Dx 62; RLP 4/20/09

Biopsy - Invasive moderately differentiated prostatic andenocarconoma; G 3+3=6; PT2C; No evidence of Seminal Vesicle or Extraprostatic Involvement; Margins clear; Tumor identified in sections from prostatic apex. 70 gram prostate. Continent after removal of cath.

ED - Trimix works well; levitra @ 90%
PSA - 7/31/09 <0.06; 12/1/09 <0.06; 3/29/10 <0.06; 8/4/10 <0.06

Regular Member

Date Joined Jul 2010
Total Posts : 33
   Posted 10/15/2010 6:48 AM (GMT -6)   
Stick with the pills. They are a lot cheaper and are mostly covered by insurance plans.
Age 49 years old with no family history of PCa. but had testicular cancer in 1985.

PSA on 3-8-2010 was a 5.6
PSA re-take on 3-17-2010 was a 4.4
Biopsy collected on 4-17-2010 showed 2 of 12 cores malignant with Gleason scores of 3+3 Stage T1C.
RALP surgery 7-21-2010 at Hopkins.
Pathology report revealed that the cancer was organ confined, all margins negative and a Gleason score of 6.

gold horse
Regular Member

Date Joined Nov 2009
Total Posts : 360
   Posted 10/15/2010 7:57 AM (GMT -6)   
I told my doc that viagara made me see kind of blue and he told me not to take viagra and changed it to cealis. shocked smurf
smurf shocked eyes cry

Steve n Dallas
Veteran Member

Date Joined Mar 2008
Total Posts : 4849
   Posted 10/15/2010 8:01 AM (GMT -6)   

You souldn't need the pills for rehab anymore if your surgery was 4/20/09 ... You just about got what you got at this point.

Seems like a no brainer if one methods has bad side effects and the other one has none.


Age 55 - 5'11" 215lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6
06/25/08 - Da Vinci robotic laparoscopy
05/14/09 - 4th Quarter PSA -> less then .01
11/20/09 - 18 Month PSA -> less then .01
05/18/10 - 24 Month PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.
Growing old is mandatory; growing up is optional..

Worried Guy
Veteran Member

Date Joined Jul 2009
Total Posts : 3741
   Posted 10/15/2010 9:17 AM (GMT -6)   
If you get good results with a pill, why switch?

Think about this for a second.... Here's a syringe loaded with 0.2 ml of saline and a 31 gauge needle. Got it in your mind? OK.
How much would I have to pay you to stick that in your pen*s and administer the juice? $10? No way! $20? Absolutely not! $50 Maybe. $100 OK but reluctantly. Consider that as the opportunity cost of an injection.
A Viagra or Cialis is much cheaper and easier. I wish they worked for me.
In my world nothing puts a damper on amorous thoughts faster than the sight of a needle - even though it works. I'd make a poor junkie.

Steve n Dallas
Veteran Member

Date Joined Mar 2008
Total Posts : 4849
   Posted 10/15/2010 10:32 AM (GMT -6)   
Jeff - did you read the part about side effects?
The heahaches I got from the pills started the next day and lasted all day. Wasn't fun at all.
And the injections cost me about 10bucks a pop verses $15 each for the pills. (i never did the alldaychemist thing)

Regular Member

Date Joined Jun 2010
Total Posts : 74
   Posted 10/15/2010 11:33 AM (GMT -6)   
Just my two bits;  with Viagra, I experienced flashing blue lights....no side effects with Cialis, although neither type of pill worked.  So, hello tri-mix.

Age at Dx: 56
DaVinci Prostatectomy: 10/28/09

Stage: T2C

Gleason - 3+4 = 7

Prosate: 52 grams

Incontinence - absolutely at first, better with time and kegels

ED - Indeed

Married, father of two (boys 19 and 18)

11 months later: member of the "zero" club, working on one "safety" pad for 24 hours. Took Cialis for 6 months (no apparent affect), Tri-mix works, though!

Worried Guy
Veteran Member

Date Joined Jul 2009
Total Posts : 3741
   Posted 10/15/2010 12:03 PM (GMT -6)   

I did see RCS's comments about the pill side effects but, at least for me, they were preferable to the thought of sticking myself in my "naughty bit".
I can manage to think about sex with a stuffy nose, headache and blue vision. I can't when there is a syringe pointed in the direction of my wiener.
In time I will get over it, but for now, it still creeps me out.

Jeff (the wussy one)

Veteran Member

Date Joined Jul 2009
Total Posts : 504
   Posted 10/15/2010 12:13 PM (GMT -6)   
Hi Patches,

You must have great Ins, the best I saw here was 4 pills a month with a $35 co-pay for the real deal ones, after that its pay out of your own pocket

Trimix is way WAY cheaper than that and when you factor its 100% success rate its a winner

Veteran Member

Date Joined Jul 2009
Total Posts : 504
   Posted 10/15/2010 12:26 PM (GMT -6)   

You have to get with technology man , no one sticks or jabs themselves with a needle anymore, its all automatic man named Inject-Ease, you never see anything enter your skin

Now picture this, you cannot get it up, your wife says I am really ready for action could you take the Trimix option if I give you $20 ? You reply...No Honey, Making LOve to you is not worth $20, you HAVE to pay me more, much more to make love to you, give me $100 and I'll think about it. Let us know how that works out for you

Ever see a catheter get inserted ??? any you are worried about an auto-injector

Regular Member

Date Joined Aug 2010
Total Posts : 245
   Posted 10/16/2010 8:55 AM (GMT -6)   
Steve n Dallas said: "You souldn't need the pills for rehab anymore if your surgery was 4/20/09 ... You just about got what you got at this point."

Is this true? I thought healing could still take place many months later and ED still improve. We're a more than 3 months post RP and nothing usable yet with Viagra...
Husband 60yrs., no symptms: PSA 10/04 2.73, 12/06 3.64, 5/09 3.9, 10/09 4.6, 1/10 5.0w/ free PSA 24
6 core biop 4/1/10 path rept: rt mid: adnocarc. G=3+3, 5% of core; R apx v. susp. minute ca, R base bnign w/ mod. atrophy, L side atrphy only; 2nd opnion JH confrmd
MRI - 15mm nodule
BiLatRP surg 7/6/10, path: T2c, nodes, sem.ves, extra caps. neg., adenoc both sides G=3+3 cntinent, Viagr-8/27 ED

Veteran Member

Date Joined Jul 2006
Total Posts : 686
   Posted 10/16/2010 1:02 PM (GMT -6)   
The pills do not work for me and give me a major headache.  I have no problem injecting, it works 100%.  I use Bi-Mix and it is much, much cheaper than even the imported pills.  If my calculations are right, my cost is about $3.00 per .15 use including the syringe.
I understand that some people are not as comfortable using a needle. 
PSA July 2006 4.7 , Nodule found
biopsy 10/06 very agressive gleason4+4=8 identified
DaVinci surgery, Sutter Hospital, Sacramento, Ca. January 2007
Post Ob confirms, gleason 4+4=8 with no extension or invasion
no long term continence problems
post surgery PSA continues to be undetectable at 3 years
ED continues, using bimix
born 1941

Worried Guy
Veteran Member

Date Joined Jul 2009
Total Posts : 3741
   Posted 10/16/2010 5:13 PM (GMT -6)   
Mr Gimpy,

I do use the Autoinjector. It still creeps me out, even though I know it is no big deal.
If my wife ever said "I am really ready for action", I'd stick myself faster than a junkie coming out of rehab! The problem is, after dinner and movie, the thought of me initiating any process that includes sticking myself is outweighed by simply falling asleep while spooning. Sigh...


Steve n Dallas
Veteran Member

Date Joined Mar 2008
Total Posts : 4849
   Posted 10/17/2010 5:08 AM (GMT -6)   
NEIrish - my surgeon said two years was pretty much the end of the healing process. RCS is at 18 months....I'd guess that the odds of something major changing at 18 months sre pretty slim.

Cajun Jeff
Veteran Member

Date Joined Mar 2009
Total Posts : 4119
   Posted 10/17/2010 7:45 PM (GMT -6)   
I have heard the same thing but I must say that month 220-24 had made some differences for me. Im still hoping for a bit more.

Cajun jeff
9/08 PSA 5.4 referred to Urologist
9/08 Biopsy: GS 3+4=7 1 positive core in 12 1% cancer core
10/08 Nerve-Sparing open radicalSurgery Path Report Downgrade 3+3=6 GS Stage pT2c margins clea
r3 month: PSA <0.1
19th month: PSA <0.1
Only issue at this time is ED

Veteran Member

Date Joined Dec 2009
Total Posts : 1268
   Posted 10/20/2010 7:23 PM (GMT -6)   
I'd like to thank everyone for their input.  I've been on the road and haven't been able to get back to the forum untill now.
I think I've found the answer ... use half a pill! .... Seems to work for me with no side effects.
One commentor indicated that at 18 months you would probably have all the ED improvement you could expect ... I do not think this is correct.  I've spoken to guys who have had improvement after 2.5 years! Pills didn't work for me until after 14 months and now they work real well (except the side efffects).  I plan on continuing penile rehab (use of low dose pills to increase oxygen flow to the penise) for 3.0 years or until I get regular nocturnal erections ... which ever comes first.
Concerning injections ... I really like them and recommend anyone who has ED problems (from surgery) give careful consideration to the use of injections per Dr. Muhall's guidance (see his book on Saving your sex life).  On the use of the injector ... I tried it but quite ... its much easier to just inject.
Thanks for your suggestions.
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