After my radiation tx the Rad Onc surprised my by saying he wants me to be on HT for three years (he was saying six months prior to tx). It took me a while to get used to that thought. I've been visiting Sloan Kettering quarterly for over a year now. Last time my Radiologist must have had enough of me and said I should follow up with the Onc. (Both are from Sloan Kettering). Today was supposed to be my Lupron shot, so I saw my Onc doc.
She surprised me again by saying in her experience for younger men like myself, the risks of staying on HT (PCa becoming hormone resistant) are higher than the risks of limiting the treatment to a year after the radiation. She said there is no evidence that three years is better than one or two. (There is evidence of that in the case of primary rad treatment). She also said that should the cancer return after my T levels rise to normal, she would treat me with Casodex intermittently.
On one hand, I am pleased to be off the HT (the end of hot flushes and all), but on the other hand, I am uncertain which path is better.
Can you guys chime in with your thoughts?
P.S. T and PSA are still undetectable
Father died from poorly differentiated PCa @ 78 - normal PSA and DRE
5 biopsies over 4 years negative while PSA going from 3.8 to 28
Dx Nov 2007, age 46, PSA 29, Gleason 4+4=8
Decided to participate in clinical trial at Duke - 6 rounds of chemo (Taxotere + Avastin)
PSA prior to treatment 1/8/2008 is 33.90, bounced on 1/31/2008 to 38.20, and down at the end of the treatment (4/24/2008) to 20.60
RRP at Duke (Dr. Moul) on 6/16/2008, Gleason downgraded 4+3=7, T3a N0MX, focal extraprostatic extension, two small positive margins
PSA undetectable for 8 months, then 2/6/2009 0.10, 4/26/2009 0.17, 5/22/2009 0.20, 6/11/2009 0.27
ADT (ongoing, duration TBD): Lupron started 6/22/2009
Salvage IMRT to prostate bed and pelvis - 72gy over 40 treatments finished 10/21/2009
PSA 6/25/2009 0.1, T=516, 7/23/2009 <0.05, T<10, 10/21/2009 <0.05, T<10
Post Edited (Geebra) : 10/19/2010 1:43:46 PM (GMT-6)