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Bob & Wife
Regular Member

Date Joined Apr 2008
Total Posts : 100
   Posted 11/3/2010 10:24 PM (GMT -6)   
Got my psa results back from my test yesterday and it is up .4 in 5 weeks. Since August it has gone from .19 to.38 up .19 so now we wait for the additional tests and doctor appointment on the 30th. I have looked online but still not sure how to figure my doubling time and when I do get the results what it means. I plan to have this discussion with my doctor on the 30th. Can anyone explain to me what the doubling time means and how to understand it. Thanks so much Bob

Ed C. (Old67)
Veteran Member

Date Joined Jan 2009
Total Posts : 2461
   Posted 11/3/2010 10:52 PM (GMT -6)   
Bob & wife,
What treatment did you have? If it was surgery, what was your pathology report?
Age: 67 at Dx on 12/30/08 PSA 3.8
2 cores out of 12 were positive Gleason (4+4)
Davinci surgery 2/9/09 Gleason 4+4 EPE,
Margins clear, nerve bundles removed
Prostate weighed 57 grams 10-20% involved
all PSA tests since (2, 5, 8, 11, 15, 18 months) undetectable
Latest PSA test (21 months) .005

Veteran Member

Date Joined Apr 2008
Total Posts : 847
   Posted 11/3/2010 11:31 PM (GMT -6)   
The PSA doubling time is the time it takes for the PSA to double and is a measure of how quickly your cancer is advancing. Your PSA has doubled since 10 August, which means a doubling time of a little under 3 months. Your last rise of 0.04 in 5 weeks is broadly consistent with that.

As it is a fairly short doubling time, (= a fairly rapid advancement) you will need to take some action -- normally this could be radiation, but as you have already had that (I think), your next most likely treatment is some form of Hormone Therapy. There is no particular rush for this.

Good luck for the 30th.

Bob & Wife
Regular Member

Date Joined Apr 2008
Total Posts : 100
   Posted 11/5/2010 9:07 AM (GMT -6)   
Thanks for helping me understand the doubling time. Now we will wait for the ct scan and full body scan to see what the next course will be. Did not think I would be at this point after doing the surgery and radiation. My path report after surgery sounded so encouraging and even with the rise again in my psa we thought after radiation it was a localized reaccurance and this would take care of it. You never know what this ugly stuff will do. Thanks again Bob

Veteran Member

Date Joined Nov 2009
Total Posts : 1100
   Posted 11/5/2010 9:57 AM (GMT -6)   
Many people get the psa doubling time calculation wrong. An on-line calculator can help. Here's one from MSKCC:
Age 46.  Father died of p ca. 
My psa starting age 40: 1.4, 1.3, 1.43, 1.74, 1.7, 1.5, 1.5
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