Transient causes of elevated PSA level (pre treatment)

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English Alf
Veteran Member

Date Joined Oct 2009
Total Posts : 2217
   Posted 11/10/2010 3:47 AM (GMT -6)   
People at the early part of their PCa journey have often asked what things should they avoid before having a PSA test as they have heard that some things can make your PSA go up (and thus give you a higher result than what may be your normal PSA level) for instance how long after a biopsy or DRE should they wait before getting their PSA retested

Billymac posted a link to an article in an Australian medical journal about PCa (see this thread)

In the article is a table about things that can make your PSA go up - were talking here about when you are getting your regular PSA tests before treatment. It also gives an indication of how long it takes for you PSA to settle down again.

I thought it would be helpful to put those details here:

Activity/Condition - - - - - - Time taken for PSA to return to baseline level

DRE-------------------------------------------------- less than 24 hours
Ejaculation ----------------------------------------- 48 hours
Cycling (perineal trauma)* ---------------------- 48 hours
Bacterial prostatitis/Urinary infection --------- 8 to 12 weeks
Prostate biopsy ----------------------------------- 6 weeks
Acute urine retention ----------------------------- 2 weeks

(*I would also reckon that riding a motorbike or a horse falls in this category too)

I hope this info is of use.

Born Jun ‘60
Apr 09 PSA 8.6
DRE neg
Biop 2 of 12 pos
Gleason 3+3
29 Jul 09 DaVinci AVL-NKI Amsterdam
6 Aug 09 Cath out
PostOp Gleason 3+4 Bladder neck & Left SVI -T3b
No perin’l No vasc invasion Clear margins
Dry at night
21 Sep 09 No pads daytime
17 Nov 09 PSA 0.1
17 Mar 10 PSA 0.4 sent to RT
13 Apr 10 CT
28 Apr 10 start RT 66Gy
11 Jun 10 end RT
BMs weird
14 Sep 10 PSA <0.1
Erections OK

Post Edited (English Alf) : 11/10/2010 1:53:43 AM (GMT-7)

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