PSA at one year from brachytherapy

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Sancarlos
Regular Member


Date Joined Feb 2010
Total Posts : 242
   Posted 11/15/2010 5:11 PM (GMT -6)   
I just got the results from my latest PSA test, which is one year after brachytherapy. It was 0.013, down from 0.06 in August. I am still on HT but even so I welcome this as very good news. Course, it would be much better news if I were not on HT but the oncologists tell me I need it.

Would also add that after adding iron and B vitamin supplements my energy level has been quite high, even with the HT. In fact, other than hot flashes I would say that at this time I am not experiencing any negative side effects from the HT.

I do recommend that new PCa patients strongly consider brachytherapy. I experienced virtually no bad side effects from it and so far I am very pleased with the outcome.

Sancarlos
Age 66, PC diagnosed 7/2009 at age 65
Stage: T2c, Gleason: 9 (4 + 5), 6 of 6 cores positive
Bone, CAT and MIR scans negative

Treatment: brachytherapy (103 palladium), 100 gy, 11/2010 + hormone therapy (Lupron + Casodex) + IMRT on Novalis, 45 gy, 3/2010.

PSA: 7/2009, At time of diagnosis -- 11.9
10/2009 -- 5.0
12/2009 -- 0.56
5/2010 -- 0.15
8/9/2010 -- 0.06

Post Edited (Sancarlos) : 11/15/2010 3:19:30 PM (GMT-7)


Fairwind
Veteran Member


Date Joined Jul 2010
Total Posts : 3892
   Posted 11/15/2010 5:22 PM (GMT -6)   
That's great news SC...It's always good to hear from G-9 guys who are beating the odds. Nothing like 145Gy to beat the devil..How long are they going to keep you on HT?
Age 68.
PSA at age 55: 3.5, DRE normal. Advice, "Keep an eye on it".
age 58: 4.5
" 61: 5.2
" 64: 7.5, DRE "Abnormal"
" 65: 8.5, " normal", biopsy, 12 core, negative...
" 66 9.0 "normal", 2ed biopsy, negative, BPH, Proscar
" 67 4.5 DRE "normal"
" 68 7.0 third biopsy positive, 4 out of 12, G-6,7, 9
RRP Sept 3 2010, pos margin, one pos vesicle nodes neg. Post Op PSA 0.9 SRT, HT, Dec

Sancarlos
Regular Member


Date Joined Feb 2010
Total Posts : 242
   Posted 11/15/2010 5:59 PM (GMT -6)   
Hi Fairwind,

Thank you very much, and I hope you are doing well these days. I think about you a lot since we share that nasty G-9 experience. I don't believe I am out of the woods on this yet, but it is very encouraging to see the PSA continue to go down.

The original plan was for me to stay on HT for 2.5 to 3.0 years. I will likely still do that, especially if at some point in the next year if the PSA begins to rise. On the other hand, if the PSA continues to fall I may decide to go off HT in a year or so, to test the waters as it were.

Fortunately the side effects from HT have been very mild in my case so even if I had to stay on it the rest of my life I don't see that as a major blow to my QOL, assuming side effects at the current level.

Sancarlos
Age 66, PC diagnosed 7/2009 at age 65
Stage: T2c, Gleason: 9 (4 + 5), 6 of 6 cores positive
Bone, CAT and MIR scans negative

Treatment: brachytherapy (103 palladium), 100 gy, 11/2010 + hormone therapy (Lupron + Casodex) + IMRT on Novalis, 45 gy, 3/2010.
PSA: 7/2009, At time of diagnosis -- 11.9
10/2009 -- 5.0
12/2009 -- 0.56
5/2010 -- 0.15
8/9/2010 -- 0.06
11/2010 -- 0.013

Fairwind
Veteran Member


Date Joined Jul 2010
Total Posts : 3892
   Posted 11/15/2010 8:24 PM (GMT -6)   
I will start my HT in a few days...We can compare notes...!:)

Old Sailor
Regular Member


Date Joined Aug 2009
Total Posts : 209
   Posted 11/15/2010 9:02 PM (GMT -6)   
SC, I second what Fairwind says and hope you have beaten down the beast. Its nice to hear of a 9 doing well. You made my day since I've been in the dumps lately.  I too am a gleason 9 and failed surgery, and it looks like RT failure.   PSA now 1.0 and Mayo docs say HT is next.  Had bone scan last week and doc says one small hot spot in pelvic area, not sure what it is so MRI next.  Beginning to think that if I didn't have bad luck, I would have no luck!!
 
With hind sight in mind and being 67 when surgery occured,  I now wish I had done the seeds, I know guys that have had it with very good results and few problems.
 
I hope you continue to progress and stay well for a long, long time.
 
Old Sailor 
Dx 07/09 Age 67 - 28 core saturation biopsy w/5 positive (2 gleason 8, 2 gleason 7, 1 gleason 6)
RRP 8/13/09 Mayo Clinic Jacksonville

Path report upgraded gleason to 4+5=9

Negative margins/extraprostatic extension/seminal vessicles/ lymph nodes but perineural invasion present.

Two month post surgery PSA 0.022

Five month post surgery PSA 0.081

Seven month post surgery PSA 0.190

Eight month post surgery PSA 0.217

Started 38 sessions IMRT at Mayo Jacksonville on 4/12/10, completed 6/4/10. Few side effects except urinary urgency and frequency during the day and some rectal discomfort near the end of therapy.

Sancarlos
Regular Member


Date Joined Feb 2010
Total Posts : 242
   Posted 11/15/2010 9:39 PM (GMT -6)   
Fairwind said...
I will start my HT in a few days...We can compare notes...!:)


Fairwind,

Don't get discouraged if the HT seems hard to live with in the first weeks and months. The worst period for me came several months after I begin HT. I felt very fatigued from the anemia, and was pretty depressed. But once I recovered from the anemia things improved a lot, both physically and emotionally.

I would suggest that you have a bone density test before you start HT to serve as a benchmark. Fortunately I had one before I was diagnosed with PCa, and about a year later I had another and it confirmed bone density loss from the previous year, so now I am on Fosamax.

Also, get ready for a total loss of libido if you are not there yet.

Sancarlos
Age 66, PC diagnosed 7/2009 at age 65
Stage: T2c, Gleason: 9 (4 + 5), 6 of 6 cores positive
Bone, CAT and MIR scans negative

Treatment: brachytherapy (103 palladium), 100 gy, 11/2010 + hormone therapy (Lupron + Casodex) + IMRT on Novalis, 45 gy, 3/2010.
PSA: 7/2009, At time of diagnosis -- 11.9
10/2009 -- 5.0
12/2009 -- 0.56
5/2010 -- 0.15
8/9/2010 -- 0.06
11/2010 -- 0.013

Sancarlos
Regular Member


Date Joined Feb 2010
Total Posts : 242
   Posted 11/15/2010 9:51 PM (GMT -6)   
Old Sailor,

Don't second guess your decision for treatment. With the salvage radiation and HT it could well turn out in the end to have been the right decision for you.

BTW, even though I am from South Carolina I had my seed implant surgery done in Jackonsville by someone I consider one of the best in the business. I don't believe it is appropriate to share that kind of information on the forum but if anyone is interested get in touch with me by pm and I will be happy to provide contact information.

Sancarlos
Age 66, PC diagnosed 7/2009 at age 65
Stage: T2c, Gleason: 9 (4 + 5), 6 of 6 cores positive
Bone, CAT and MIR scans negative

Treatment: brachytherapy (103 palladium), 100 gy, 11/2010 + hormone therapy (Lupron + Casodex) + IMRT on Novalis, 45 gy, 3/2010.
PSA: 7/2009, At time of diagnosis -- 11.9
10/2009 -- 5.0
12/2009 -- 0.56
5/2010 -- 0.15
8/9/2010 -- 0.06
11/2010 -- 0.013

fulltlt
Regular Member


Date Joined Nov 2010
Total Posts : 264
   Posted 11/16/2010 9:16 PM (GMT -6)   
Sancarlos,

I'm confused by the dates you list in your signature. When did you have the brachytherapy done? IMRT? I see your PSA going down all through 2009 following your diagnosis.
age 57 2/2010
PSA 8.2 2/2010
Gleason 3+4=7
second opinion on pathology from John Hopkins 4+4=8
PSA 15 4/2010
5 weeks EBRT 4/2010-6/2010
91 implants of palladium 103 7/2010
PSA 3.97 10/2010

Sancarlos
Regular Member


Date Joined Feb 2010
Total Posts : 242
   Posted 11/17/2010 12:28 AM (GMT -6)   
Hi Fulltilt,


Sorry for the confusion. When I edited the profile to include the last PSA result I mistakenly changed the date of the brachytherapy from 11/2009 to 11/2010. I have corrected the error on the profile but the system appears to take some time to recognize the change.

Sancarlos
Age 66, PC diagnosed 7/2009 at age 65
Stage: T2c, Gleason: 9 (4 + 5), 6 of 6 cores positive
Bone, CAT and MIR scans negative

Treatment: brachytherapy (103 palladium), 100 gy, 11/2010 + hormone therapy (Lupron + Casodex) + IMRT on Novalis, 45 gy, 3/2010.
PSA: 7/2009, At time of diagnosis -- 11.9
10/2009 -- 5.0
12/2009 -- 0.56
5/2010 -- 0.15
8/9/2010 -- 0.06
11/2010 -- 0.013
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