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Date Joined Mar 2009
Total Posts : 739
   Posted 11/20/2010 8:16 PM (GMT -6)   
Found in another thread, new member "RLG"...............................Kev

Hi everyone,
I am new to this. I have been on Avodart for several years (enlarged prostate) and the readings taking every six months have been between 1.0 to 1.5. My last test jumped from 1.3 to 2.1 and the urologist wants to do a biopsy. I had a biopsy 8 years ago and it was negative. Should the increase in PSA be a matter of great concern? I read somewhere that PSA reading should be multiplied by 2 when taking Avodart.
Age 67

Post Edited (NotHard) : 11/20/2010 10:14:55 PM (GMT-7)

Veteran Member

Date Joined Jul 2010
Total Posts : 3892
   Posted 11/20/2010 9:00 PM (GMT -6)   
Thanks Kev, I saw that too..

Okay Rig, welcome to HealingWell..Maybe your stay here will be temporary, we all hope so. I would be a little worried about the PSA jump, it's actually 4.2 something like that..How was your DRE? Some U-docs are much better at feeling things than others..I'm SURE you are not looking forward to another biopsy, but, sadly, that's still the only way to be sure..There are some advanced diagnostic techniques, Color Doppler Ultrasound is one, that sometimes can spot cancer better than the standard ultrasound equipment..You might have to travel to find a doctor who uses it..

If you are really hesitant about the biopsy you could start having a PSA test every month for the next three months and watch the trend line (called PSA velocity). When taking drugs like Avodart, PSA tends to creep down in healthy men or hold steady. If yours continues to rise, that's an alarm bell...

There are several other reasons PSA can jump..Infection, having sex before the test, bicycle riding, horseback riding all can irritate the prostate and cause the PSA number to jump..The DRE should always be done AFTER they draw blood for the test..

Since you are here looking for information, you might want to read one or more of the books listed in the first 3 or 4 threads..Dr. Walsh's "Guide to Surviving Prostate Cancer" is my favorite..But this might not be the best thing to do until you are actually diagnosed..If you are prone to anxiety attacks, forget the book...Again, welcome and Good Luck!
Age 68.
PSA at age 55: 3.5, DRE normal. Advice, "Keep an eye on it".
age 58: 4.5
" 61: 5.2
" 64: 7.5, DRE "Abnormal"
" 65: 8.5, " normal", biopsy, 12 core, negative...
" 66 9.0 "normal", 2ed biopsy, negative, BPH, Proscar
" 67 4.5 DRE "normal"
" 68 7.0 third biopsy positive, 4 out of 12, G-6,7, 9
RRP Sept 3 2010, pos margin, one pos vesicle nodes neg. Post Op PSA 0.9 SRT, HT, Dec

Veteran Member

Date Joined Mar 2009
Total Posts : 739
   Posted 11/20/2010 9:05 PM (GMT -6)   
No Probs Fairwind, and I think you have nailed this one, good post..............Kev

New Member

Date Joined Nov 2010
Total Posts : 11
   Posted 11/20/2010 10:57 PM (GMT -6)   
Fairwind; Thanks so much!
I will go with the biopsy asap. Is there a particular type of biopsy that I should ask for?

Veteran Member

Date Joined Jul 2010
Total Posts : 3892
   Posted 11/21/2010 12:12 AM (GMT -6)   
How did they do your last one?? Things may have changed a little in 8 years, maybe not.. Today, it's done with an ultrasound wand inserted through your rectum..Bring back any fond memories?? First they use the probe to map your prostate, take a good look at it, determine its size, then they "numb you up" with a couple of shots of anesthetic and then click, click, click, twelve little clicks and it's over..(sort of over)

So to answer your question, the standard biopsy today is the 12 core ultrasound guided biopsy.. They divide your prostate up into 12 sections and take a sample from each section. If you have PC, 90% of the time the first biopsy will find it..Sometimes, the doctor will take a couple of extra samples from suspicious areas..The 12 cores get put in little glass tubes, are marked, and in a special container are sent to a pathology lab. If cancer is found, they know exactly where in your prostate it came from..

Let us know how all this turns out ...I hope we have helped you..
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