Prostate Staging level Question

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Regular Member

Date Joined Nov 2010
Total Posts : 102
   Posted 11/23/2010 10:05 AM (GMT -6)   
I am 67 yrs. old and a Gleason 4+4= 8. Recent Robotic prostectomy. I have been trying to understand my pathology report. The part that stumps me the most is the AJCC Pathologic TNM Stage which is pT3 pNO. Can someone kindly explain what these numbers mean. I will include some additional information should this be necessary in determining the Pathologic TNM Stage.
Margin involvement: Present
Tumor location: Right and left lobes
Perineural invasion: Present
Additional Pathologic Findings: Glandular and Stromal Hyperplasia
Single reactive lymph node showing no evidence of metastatic prostatic adenocarcinoma
PSA score 4.5
My sincere appreciation for your time and caring response.
Stay well and blessed
T Taylor

James C.
Veteran Member

Date Joined Aug 2007
Total Posts : 4462
   Posted 11/23/2010 10:34 AM (GMT -6)   
pT3 = Extraprostatic extension--- cancer cells were detected outside the prostate gland itself- usually means positive margin seen (below sig. says margin involvement present)

pNo = No positive regional nodes---there was no evidence that the cells had spread into the other areas around the prostate- ie-the prostate beds region, the bones, etc. (There was one lymph nodes that reacted to the staining, but no sign of PCa spread was seen on it.)

I hope I got that right, others will be glad to correct me if I didn't.. smilewinkgrin
James C. Age 63
Gonna Make Myself A Better Man
4/07: PSA 7.6, 7/07 Biopsy: 3 of 16 PCa, 5% involved, left lobe, GS6
9/07: Nerve Sparing open RRP, Path: pT2c, 110 gms., all clear except:
Probable microscopic involvement of the left apical margin -GS6
3 Years: PSA's .04 each test until 04/10-.06, 09/10-.09- Uh-Oh
ED continues: Bimix .30cc & Trimix .15cc PRN

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 11/23/2010 1:14 PM (GMT -6)   
I just posted the lastest staging by AJCC. Please see the link below:

I think it's time to make a sticky for the diagnostic aspects of prostate cancer and include that and a few other links.

Advanced Prostate Cancer at age 44 (I am 48 now)
pT3b,N0,Mx (original PSA was 19.8) EPE, PM, SVI. Gleason 4+3=7

RALP ~ 2/17/2007 at the City of Hope near Los Angeles.
Adjuvant Radiation Therapy ~ IMRT Completed 8/07
Adjuvant Hormone Therapy ~ 28 months on Casodex and Lupron.

"I beat up this disease and took its lunch money! I am in remission."
I am currently not being treated, but I do have regular oncology visits.
I am the president of an UsTOO chapter in Las Vegas

Blog :

Veteran Member

Date Joined Apr 2008
Total Posts : 1382
   Posted 11/23/2010 7:06 PM (GMT -6)   
I think Tony's link should answer the question.

My PSA at diagnosis was 16.3
age 47 (current)

My gleason score from prostate was 4+5=9 and from the lymph nodes (3 positive) was 4+4=8
I had 44 IMRT's
I was on Lupron, Casodex, and Avodart for two years with my last shot March 2009. I am currently (7-22-2010) not on any medication.
My Oncology hospital is The Cancer Treatment Center of America in Zion IL
PSA July of 2007 was 16.4
PSA May of 2008 was.11
PSA July 24th, 2008 is 0.04
PSA Dec 16th, 2008 is .016
PSA Mar 30th, 2009 is .02
PSA July 28th 2009 is .01
PSA OCt 15th 2009 is .11
PSA Jan 15th 2010 is .13
PSA April 16th of 2010 is .16
PSA July 22nd of 2010 is .71
Testosterone keeps rising, the current number is 156, up from 57 in May

T level dropped to 37 Mar 30th, 2009
cancer in 4 of 6 cores

English Alf
Veteran Member

Date Joined Oct 2009
Total Posts : 2209
   Posted 11/24/2010 11:06 AM (GMT -6)   
While (Tony's link to) the poster explains the codes, in case it's not obvious you should note that the difference between "pT2" and "T2" etc is because the little "p" means this is a real stage derived from examining the whole prostate in a pathology lab after surgery rather than an "estimate" of the stage based on a DRE, scan etc

(I mention this as there was a time when I couldn't work out what it meant)


Forum Moderator

Date Joined Jan 2010
Total Posts : 6856
   Posted 11/24/2010 9:07 PM (GMT -6)   
Good point to make, I had to work out that "p" myself a while back.

I was going to suggest that be added (at least) to the terms/ abbreviations sticky, but got sidetracked by my real (ok, provides insurance and a long day at the office) work -
DaVinci 10/2009
My IGRT journey (2010) -
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