Welcome New Member--Frogman

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Regular Member

Date Joined Aug 2009
Total Posts : 374
   Posted 12/1/2010 5:17 PM (GMT -6)   
Frogman posted the following in the signature thread on 11/5.......doesn't look like he's had any responses.
I'm new to this site. Age 66 and have been diagnosed with enlarged prostate for many years. Just came from Urologist who indicated thickening of the prostate on one side, something he had not noticed in past annual DREs. PSA was below 1 until 2003, when it jumped to over 4 for no reason; endured biopsy at that time- negative. Subsequent PSAs were 1.4, but jumped to 2.4 last year, and was 2.4 again this year, but DRE finding has doctor concerned and wants to do another biopsy. Does anyone have any insight on how concerned I should be and whether I should have the biopsy done or wait 6 months for another PSA test and DRE?
Welcome to the forum, Frogman. Sounds like your urologist has been on top of your situation for a while. With that as a backdrop, I would probably opt for a biopsy, if it were me, since he's already done one, and seems concerned with the DRE finding. Personally I'd rather know as early in the game as possible, so you can begin to consider all options---if in fact the biopsy is positive. Hopefully others will be along soon to share their opinions.
Arnie in DE

Elite Member

Date Joined Oct 2008
Total Posts : 25393
   Posted 12/1/2010 5:55 PM (GMT -6)   
Welcome, Frog, I agree with Arnie, with what you said, I would go for another biopsy to be on the safe side
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 Not taking it
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/23/10

Regular Member

Date Joined Sep 2010
Total Posts : 38
   Posted 12/1/2010 6:39 PM (GMT -6)   
Welcome Frogman, Better safe than sorry, I agree with Arnie and Purgatory
Age 42 PSA 7.4 4+4 G8
Davinci Sept.8 2010
No incontinence issues but ED issues
1st post surgery PSA <.008

Veteran Member

Date Joined Apr 2009
Total Posts : 990
   Posted 12/1/2010 8:26 PM (GMT -6)   
I note you said you "endured" your previous biopsy. If you do opt for another biopsy be sure to discuss pre-medication with your doctor.

Your PSA is pretty low for another biopsy, but your doctor is judging based on his previous experiences with DREs. You should give strong consideration to his expertise.

Regular Member

Date Joined Sep 2010
Total Posts : 309
   Posted 12/1/2010 8:42 PM (GMT -6)   
Welcome to the forum, Frogman. If you were my husband, I would want you to have a second biopsy. I know they are no fun, but it is common for one or even two biopsies to detect nothing when there is actually cancer present.

If your doctor actually thinks he feels something, and if he actually expressed concern, that would be enough for me. Otherwise, you might ask him about the possibility of a free psa test to help narrow down the issue.

Please come back and let us know how it goes. I wish you the best.


Veteran Member

Date Joined Jul 2010
Total Posts : 3892
   Posted 12/1/2010 8:52 PM (GMT -6)   
Frog may have swam away but if not, it might be worth traveling to a specialist who uses color doppler ultrasound and have him take a look at your prostate and he might be able to sort it out without (or perhaps with) a second biopsy..

I agree...When a U-doc detects a change in a DRE, SOMETHING is going on and the sooner you find out what it is the better...You survived one biopsy, you can survive another..
Age 68.
PSA at age 55: 3.5, DRE normal. Advice, "Keep an eye on it".
age 58: 4.5
" 61: 5.2
" 64: 7.5, DRE "Abnormal"
" 65: 8.5, " normal", biopsy, 12 core, negative...
" 66 9.0 "normal", 2ed biopsy, negative, BPH, Proscar
" 67 4.5 DRE "normal"
" 68 7.0 third biopsy positive, 4 out of 12, G-6,7, 9
RRP Sept 3 2010, pos margin, one pos vesicle nodes neg. Post Op PSA 0.9 SRT, HT, Dec

James C.
Veteran Member

Date Joined Aug 2007
Total Posts : 4463
   Posted 12/2/2010 11:12 AM (GMT -6)   
Welcome, frogman to HW. Sorry you got lost up in the signature area, that's an area that isn't usually looked at on a daily basis. Anyway, I hope you will stick around and find what you are looking for here with us.
James C. Age 63
Gonna Make Myself A Better Man tinyurl.com/28e8qcg
4/07: PSA 7.6, 7/07 Biopsy: 3 of 16 PCa, 5% involved, left lobe, GS6
9/07: Nerve Sparing open RRP, Path: pT2c, 110 gms., all clear except:
Probable microscopic involvement of the left apical margin -GS6
3 Years: PSA's .04 each test until 04/10-.06, 09/10-.09- Uh-Oh
ED continues: Bimix .30cc & Trimix .15cc PRN
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