Chronic radiation proctitis

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Regular Member

Date Joined Jan 2009
Total Posts : 390
   Posted 12/2/2010 5:57 PM (GMT -6)   
Hi guys,
As if my disease level were not depressing enough , it appears as if I have developed chronic radiation proctitis. It began a few months ago (about 6 monthhs after the completion of my salvage IMRT) as just a smear of blood on the tissue post BM, and has recently progressed into a significant amount of blood several times a week. Seeing my onc to begin HT next week and this will obviously be addressed. Anyone have experience with this problem?

Age 61
Northeastern Penna.
11/08/08 annual checkup (3 yrs late) PSA 8.04 from previously 2.7 in 11/05
1/23/09 biopsy 12 cores positive, 10 cores Gleason 7, 2 cores Gleason 8 70% tumor
2/06/09 cat +bone scans clean ..
3/26/09 RRP surgery Post op path .. upgraded to Gleason 9 (5+4), seminal vesicles involved, several positive margins, 2 of 9 lymph nodes positive.

80% involved
4/4/09 Dr. advising wait for significant rise in PSA and start hormonal treatment.

1st post op at 4 weeks PSA .6 urologist concerned

will retest in one month

8/15/09 bone and pelvic scans redone .. clean PSA .65

onc/radiologist recommending starting radiation treatments and 6 month shot of Lupron .. decided against this gameplan

9/11/09 consulting with med/onc today .. not impressed
My urologist now suggesting prostascint scan

Prostascint test done at U of Penna indicates cancer still confined to prostate bed.

PSA at .7
Gonna need a bigger boat .. found a good rad oncologist

10/21/09 Rad onc suggesting clinical trial of samarium 153 followed by IMRT

2/1/10 Samarium trial completed PSA 1.0

2/1/10 began IMRT 39 treatments 70 Gy

3/25/10 finished IMRT

4/28/10 PSA .93

7/23/10 PSA 1.2

John T
Veteran Member

Date Joined Nov 2008
Total Posts : 4268
   Posted 12/2/2010 9:29 PM (GMT -6)   
Bleeding is usually caused by damage to the blood vessles near the surface. The most common treatment is to not intervene and have it resolve itself over time. If it is really serious then hypobaric oxygen treatments are effective. Most bleeding stops by itself.
65 years old, rising psa for 10 years from 4 to 40; 12 biopsies and MRIS all negative. Oct 2009 DXed with G6 <5%. Color Doppler biopsy found 2.5 cm G4+3. Combidex clear. Seeds and IMRT, no side affects and psa .1 at 1.5 years.

Regular Member

Date Joined Mar 2010
Total Posts : 46
   Posted 12/2/2010 10:00 PM (GMT -6)   
My husband suffered radiation proctitis toward the end of his treatments and for some time afterwards.  His radiation oncologist referred him to our gastroenterologist for treatment.  The gastroentereologist prescribed a course of Mesalamine enemas, given at bedtime nightly for about 4 weeks.  The enema is small, only 60ml, and is to be retained overnight if possible.  This treatment, although not fun for either hubby or me, who had the job of administering them, was very effective and his proctitis completely resolved.
about 2 months later, just a few weeks ago, hubby had a colonoscopy to check for any hidden problems.  I'm pleased to report that everything was fine and back to normal - we even have the pictures to prove it!!

English Alf
Veteran Member

Date Joined Oct 2009
Total Posts : 2217
   Posted 12/3/2010 2:35 AM (GMT -6)   
Oncas sorry to hear about this unpleasant problem.
It's something I'm hoping I will avoid, although my doc said that my bowel problems (frequency/urgency) would clear up 6 months after RT.
So Margie I'm glad to hear there may be a (relatively) straightforward way of alleviating it if it does come my way. Given all the things that have been shoved in me I think I could cope with a few 60ml enemas. I have made a note of Mesalamine, and have in fact also added it to my sticky thread at the top of the page as this definitely sounds like "useful information".

Born Jun ‘60
Apr 09 PSA 8.6
DRE neg
Biop 2 of 12 pos
Gleason 3+3
29 Jul 09 DaVinci AVL-NKI Amsterdam
6 Aug 09 Cath out
PostOp Gleason 3+4 Bladder neck & Left SVI -T3b
No perin’l No vasc invasion Clear margins
Dry at night
21 Sep 09 No pads daytime
17 Nov 09 PSA 0.1
17 Mar 10 PSA 0.4 sent to RT
13 Apr 10 CT
28 Apr 10 start RT 66Gy
11 Jun 10 end RT
BMs weird
14 Sep 10 PSA <0.1
Erections OK

Post Edited (English Alf) : 12/3/2010 12:43:05 AM (GMT-7)

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