A new member Lilosmom posted in a very old thread (these must pop up with a googe search)
"Anyone know anything about
newly released research that says rapid increases in PSA (>2.0 in one year) resulted in increased chance of death within 7 years? Study was done by Washington University in St. Louis and I believe John Hopkins. Don't want to discuss with my husband -- don't want to worry him. Hard to meet with doctor without him around...
Husband diagnosed August 2010
Biopsy 2% positive in 1 sample of 12
High detail MRI - two tumors, prostate wall intact
iodine seeds inserted 12/1/2010"
his stats are good ie 3+3, 1 off 12 positive but with very little tumour. Without knowing his age it is hard to make suggestions but a great number of men over 50 would have those same stats and never know of it nor have treatment. It would be wise to eliminate any other reasons for the PSA increase (inflammation, BPH etc). Even some physical activities and having sex can effect the readings if carried out shortly before. Don't panic, there is much to be learned before he needs (if ever) to take any action.
4 of 10 cores positive for Adenocarcinoma-------bummer!
Core 1 <5%, core 2----50%, core 3----60%, core 4----50%
Biopsy Pathologist's comment:
Gleason 4+3=7 (80% grade 4) Stage T2c
Neither extracapsular nor perineural invasion is identified
CT scan and Bone scan show no evidence of metastases
Da Vinci RP Aug 10th 2007 Post-op
Positive for perineural invasion and 1 small focal extension
Negative at surgical margins, negative node and negative vesicle involvement
Some 4+4=8 identified ........upgraded to Gleason 8
PSA Oct '07 <0.1 undetectable
PSA Jan '08 <0.1 undetectable
PSA April '08 <0.001 undetectable (disregarded due to lab "misreporting")
PSA August '08 <0.001 undetectable (disregarded due to lab "misreporting"-----it is not possible for any lab to get a reading of less than .003) Post-op pathology rechecked by new lab:
Gleason downgraded to 4+3=7
Focal extension comprised of grade 3 cells
PSA September '08 <0.01 (new lab)
PSA February 09 <0.01
PSA May '10 <0.01www.yananow.net/Mentors/BillM2.htm
Never underestimate old people ............ you don't get to be old by being stupid.