UC Riverside Researchers Identify Components in Pomegranate Juice That Could Stop Cancer From Spread

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BobCape
Regular Member


Date Joined Jun 2010
Total Posts : 416
   Posted 12/12/2010 10:24 AM (GMT -6)   
For My Pomegranate interested brothers...
 
 
 

BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 12/12/2010 10:49 AM (GMT -6)   
This is great news Bob. Thanks for posting it. Any indication if the compounds that they have identified are present in Ponagranet extract (pills) or just in the form of juice?
Dx PCa Dec 2008 at 56, PSA 3.4
Biopsy: T1c, Geason 7 (3+4) - 8 cores, 4 positive, 30% of all 4 cores.
Robotic Surgery March 2009 Hartford Hospital, Dr Wagner
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes negitive - tumor volume 9%, nerves spared, no negitive side effects of surgery.
PSA's < .01, .01, .07, .28, .50. HT 5/10. IMRT 9/10.
PSA's post HT .01, < .01

John T
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Date Joined Nov 2008
Total Posts : 4188
   Posted 12/12/2010 12:27 PM (GMT -6)   
There are quite of few discoveries in lab settings that some how never translate to real life. That said, there have been various small studies that show that pomegranite slows progression of PC and delays reoccurrances after treatment. None of this is overwhelming evidence that Pomegranite is effective for PC. I believe that if something shows early promise and doesn't harm you then you have nothing to lose by trying it and a lot to gain. I've been taking pomegranite extract for about 2 years. The extract is inexpensive and may be the reason my psa dropped 10 points before treatment and held my psa to .1 after treatments. I'll never know, but it sure hasn't caused me any harm. There are a lot of variations in PC and it is not hard to believe that some of these variations may react to pomegranite just as some variations react favorably to other drugs.
JT
65 years old, rising psa for 10 years from 4 to 40; 12 biopsies and MRIS all negative. Oct 2009 DXed with G6 <5%. Color Doppler biopsy found 2.5 cm G4+3. Combidex clear. Seeds and IMRT, no side affects and psa .1 at 1.5 years.

F8
Veteran Member


Date Joined Feb 2010
Total Posts : 3780
   Posted 12/12/2010 12:32 PM (GMT -6)   
i take a 1000mg POM pill every day.  i have a subscription.  i'm automatically sent 90 pills every 90 days and my credit card is  billed $29 a month. 
 
ed
 
 
age: 55
PSA on 12/09: 6.8
no symptoms, no prostate enlargement
12/12 cores positive....gleason 3+4 = 7
HT, BT and IGRT
received 3rd and last lupron shot 9/14/10

Carlos
Regular Member


Date Joined Nov 2009
Total Posts : 486
   Posted 12/12/2010 1:06 PM (GMT -6)   
Bob,  Thanks for posting the links.
 
F8, How did you decide how much to take?  I notice some brands suggest 500 mg as a daily serving.  I feel the same way John T does.  Its cheap and doesn't cause any harm, no downside and plenty of upside potential.
Dx 2/2008, age 71, PSA 9.1, G8,T1c. daVinci surgery 5/2008, G8(5+3), pT2c. LFPF, good QOL. PSA <0.1 for 2 yrs. PSA rose to .2 at 30 months, start SRT 12/15/2010.

F8
Veteran Member


Date Joined Feb 2010
Total Posts : 3780
   Posted 12/12/2010 1:25 PM (GMT -6)   
Carlos -- the pills only come in one size.
 
 
ed
age: 55
PSA on 12/09: 6.8
no symptoms, no prostate enlargement
12/12 cores positive....gleason 3+4 = 7
HT, BT and IGRT
received 3rd and last lupron shot 9/14/10

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25364
   Posted 12/12/2010 7:58 PM (GMT -6)   
And to remind folks that pomegrante juice/pills is no magic answer:

http://healthland.time.com/2010/09/27/ftc-and-fda-to-pom-youre-not-quite-so-wonderful/

If you like it, fine, drink it. But not going to cure or change your cancer, FDA cracked down hard on this before.
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 Not taking it
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/23/10

proscapt
Veteran Member


Date Joined Aug 2010
Total Posts : 644
   Posted 12/12/2010 8:31 PM (GMT -6)   
Without a doubt, POM overstepped the bounds of justifiable claims and got slammed for it by the FDA.

That said, there is at least some evidence that it can help in some cases: "Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer." www.ncbi.nlm.nih.gov/pubmed/16818701 (free article)

UCLA Med said...
CONCLUSIONS: We report the first clinical trial of pomegranate juice in patients with prostate cancer. The statistically significant prolongation of PSA doubling time, coupled with corresponding laboratory effects on prostate cancer in vitro cell proliferation and apoptosis as well as oxidative stress, warrant further testing in a placebo-controlled study.

Even at $7 per bottle, I'll drink to that. :-)

Authors are at the Department of Urology, David Geffen School of Medicine, University of California at Los Angeles. Disclosure: research was funded in part by pomegranate growers.

Like so much else about this disease, the evidence is ambiguous.

Post Edited (proscapt) : 12/12/2010 7:37:37 PM (GMT-7)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25364
   Posted 12/12/2010 8:53 PM (GMT -6)   
If you like how it tastes (and I think its nasty tasting), then people should drink away. Personally, I don't really drink any juices at all. I just don't like the inferred benefits that are advertised, as there is no conclusive evidence it helps in cancer, despite many folk here that believe otherwise. It won't hurt anyone to drink it, so why not if one chooses.
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 Not taking it
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/23/10

F8
Veteran Member


Date Joined Feb 2010
Total Posts : 3780
   Posted 12/12/2010 9:15 PM (GMT -6)   
>>And to remind folks that pomegrante juice/pills is no magic answer:<<
 
no one here is saying that, David.
 
ed
 

 
age: 55
PSA on 12/09: 6.8
no symptoms, no prostate enlargement
12/12 cores positive....gleason 3+4 = 7
HT, BT and IGRT
received 3rd and last lupron shot 9/14/10

BobCape
Regular Member


Date Joined Jun 2010
Total Posts : 416
   Posted 12/12/2010 9:26 PM (GMT -6)   
And Bob (me) certainly isn't among those who would suggest there was a magic answer...

However, the link to the article was due to the fact that a University of California reported..

"Researchers at the University of California, Riverside have identified components in pomegranate juice that both inhibit the movement of cancer cells and weaken their attraction to a chemical signal that promotes the metastasis of prostate cancer to the bone. The research could lead to new therapies for preventing cancer metastasis".

So they're either right, wrong or lying. I have no reason to think their lying, and i'd like to think they have evidence to substantiate their conclusions. And they would be remiss if they DIDN'T publish their findings. I think.

*I wont start daydreaming about holding my great grandchildren quite yet.

Paralleli
Regular Member


Date Joined Jul 2008
Total Posts : 123
   Posted 12/12/2010 9:43 PM (GMT -6)   
Like F8, I take a POM pill every day washed down with a cup of Joe, before I leave for work. It is the only Voodoo that I do...... can't hurt ...
IMRT 1/07 - Doing well.

mr bill
Veteran Member


Date Joined Sep 2010
Total Posts : 683
   Posted 12/13/2010 7:00 PM (GMT -6)   
Does anyone know if the pills are as good or better than the 100% juice?
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