My husband has had two doses of Firmagon and tomorrow is changing to Lupron (so the injection will last three months).
I've read about a 'flare'? after Lupron. What side effects can we expect?
Firmagon = degarelix. It blocks the production of GnRH (gonadotropin-releasing hormone) in the pituitary. This prevents stimulation of testosterone (T) by the GnRH.
Lupron directly prevents production of T.
The flare is the increase of T production upon first
dosage of Lupron, Trelstar or Zoladex. This can be damaging, especially in cases where the patient is at an advanced stage. The usual means of avoiding flare is about
a week of oral Casodex (bicalutimide) at 50 mg per day. Medics who prescribe the above three meds have a duty to be aware of this.
Dx 2004 at 67 yoa: Extensive Gleason 9 + Gleason 8.
Uro wanted to do cryotherapy, which I would have declined had I known anything. It failed, except I was rendered totally impotent; the only thing that worked as advertised.
IMRT + Lupron.
Studied PCa extensively.
Fired rad onc, who refused to read Dr. Strum's evaluation of my case.
Hired med onc. Have been on IADT since 2006.