Without knowing the post surgery pathology it is a somewhat difficult to comment other than to say your doc's anxiousness to pull the salvage radiation trigger is a little unusual at .02-.05. Most urologists would not seem to concede there has been a failure of surgery till a figure of 0.2 has been reached. There are no shortage of members here who after surgery have had readings at the 0.02 and a little higher indefinitely.
Whoops------now I re-read your post am I correct in assuming that you have already had the salvage therapy? If this is the case then stay with the ultrasensitve test ------ you have always been <0.1 since surgery so getting tested at the standard level now is not helping with seeing if the salvage had any effect on your PSA. It is important to stay with the same lab using the same testing protocols. As to your question about
aggressiveness------normally a quick doubling time of PSA indicates that the tumour cells are more aggressive. But given the figures you spoke about
i.e. 0.02 and 0.05 ...... there is a bit of variability at this very low level (particularly if different labs are involved) so I would not automatically assume that your PSA actually doubled in that time frame, despite the apparent figures.
4 of 10 cores positive for Adenocarcinoma-------bummer!
Core 1 <5%, core 2----50%, core 3----60%, core 4----50%
Biopsy Pathologist's comment:
Gleason 4+3=7 (80% grade 4) Stage T2c
Neither extracapsular nor perineural invasion is identified
CT scan and Bone scan show no evidence of metastases
Da Vinci RP Aug 10th 2007 Post-op
Positive for perineural invasion and 1 small focal extension
Negative at surgical margins, negative node and negative vesicle involvement
Some 4+4=8 identified ........upgraded to Gleason 8
PSA Oct '07 <0.1 undetectable
PSA Jan '08 <0.1 undetectable
PSA April '08 <0.001 undetectable (disregarded due to lab "misreporting")
PSA August '08 <0.001 undetectable (disregarded due to lab "misreporting"-----it is not possible for any lab to get a reading of less than .003) Post-op pathology rechecked by new lab:
Gleason downgraded to 4+3=7
Focal extension comprised of grade 3 cells
PSA September '08 <0.01 (new lab)
PSA February 09 <0.01
PSA May '10 <0.01www.yananow.net/Mentors/BillM2.htm
Never underestimate old people ............ you don't get to be old by being stupid.