4.4 to 5.2 in 2 months normal?

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Regular Member

Date Joined Nov 2010
Total Posts : 79
   Posted 1/10/2011 4:53 PM (GMT -6)   
Was wondering if a jump of 4.4 to 5.2 in 2 months is about right. My husband has PC plus acromegaly, ( production of to much growth hormone, usually steming from a pitutuary tumor)
We had a  biopsy in Oct, 4.4 gleason 7, had a 2nd read on the biopsy , came in at a 6. We were in the looking for a good doctor mode, and getting as much information as possible.. Until this acromegaly was added to the plate. We will meet the last possible surgeon, ( due to insurance ) on thursday and a appointment with a neorosurgeon next thursday to discuss the head, not sure which surgery will happen first.
The last doctor we saw for a opinion on the both matters , completely dismissed the head tumor concerning to the prostate cancer

Regular Member

Date Joined Sep 2010
Total Posts : 148
   Posted 1/10/2011 5:21 PM (GMT -6)   
4.4 to 5.2 in two months and a gleason 6. From what I've read there may be other reasons for the jump. How soon was the PSA test after the biopsy. Might still be slightly elevated. Biopsies and other prostate involvement such as digital exams and sex can do that. I am glad the second read on the gleason score went down. Might have more breathing room to take care of his pituary tumor.
Sounds like the last doctor was not much of a brain surgeon (pun intended). Ask for another PSA in a few weeks.
Best of luck
Age 48 w/diagnosed
10/06 PSA 3.0
11/06 PSA FREE %13.2
10/07 PSA 3.4
12/07 Biopsy-neg
1/09 PSA 4.6
6/09 psa 5.8
2/10 psa 8.7
7/10 PSA 10.8
8/2010 3rd biopsy GG 3+3=6, one of eight cores -2%
Lap 10/22/10 Dr. Troxel
Path- Neg Margins, Gleason 6, Nerves spared, 85 gm
Cath out Nov 2, Dec 2nd 2 pads/day

Regular Member

Date Joined Nov 2010
Total Posts : 79
   Posted 1/10/2011 6:15 PM (GMT -6)   
thank you so much for your note back, I completly forgot about the timing, His biopsy was Oct 7 , and the last psa was Dec 21.
You are also right on with the last doctor the urologist brain surgeon ,-( pun) This one was a doctor with a attitude, and not hearing anything we had concerns about , LLoooooongg visit. longer story. How long should one wait after a biopsy, would asking for another on thursday's visit be to soon . Tying not to panic, but no one has ruled out if the acromegaly is feeding on the pc. His numbers are very high for the IGF-1 hormone test 830 on one read 530 on another read ( I know that is another area, but thought I would post that info to )

Veteran Member

Date Joined Nov 2009
Total Posts : 7269
   Posted 1/10/2011 6:29 PM (GMT -6)   
That is a very unique situation.
I'm not sure if anyone on here can answer your medical questions.
Have you thought of going to a world class center such as Anderson or Mayo or MSK?

Regular Member

Date Joined Nov 2010
Total Posts : 79
   Posted 1/10/2011 7:04 PM (GMT -6)   
thanks Mel,
We do not have the best insurance and we are VERY limited to our chooses, I have found the best doctors I hope, possible in our situation. I am hopeing the uro surgeon we meet thursday , will make some conection with the neurosugoen and not dismiss it completly. I actually have been talking with the radiation doctor that found the acromegaly, and he has been very helpful. But sadly we are not selecting radiation at this time, so he is not our doctor at this time, . He also has pointed out that this is rare to have both at the same time, He suggested if we get no help to go to uconn medical center, there would be a couple of doctors willing to take him on.

Regular Member

Date Joined Nov 2010
Total Posts : 79
   Posted 1/10/2011 7:24 PM (GMT -6)   
Trying to figure out were the testosterone is produced from ...Just found this info ,,,,

The pituitary gland receives the message from the hypothalamus and releases Gn (gonadotropin) or LH (luteinizing hormone). Gonadotropin travels through the blood stream and stimulates the production of hormone in the testicles. Testosterone plugs into the receptors of the cells’ nuclei and helps them grow. The other 10 percent of testosterone is produced by the adrenal glands which are located close to the kidneys.
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