input please guys first three months on ht......

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Date Joined Dec 2010
Total Posts : 191
   Posted 1/19/2011 5:39 AM (GMT -6)   
Morning everyone, im not seeing my u doc untill next week but i have a copy of my blood results and my testosterone is down to 0.5 nmol/l which i believe is good??? however psa is not untraceable after 3 months on zoladex and is still at 20 psa (down from initial 144 psa) gleason was 4+3 =7 12 biopsies showing pc and mets in pelvis spine area nodes T3a n2 m1.Would the psa still at 20 suggest androgen independent cells or does it just take a little longer than 3 months ht for higher psa levels to drop ?
your replies would be very much appreciated as i am an impatient sort and i cant wait another week for the u docs opinion.

Steve n Dallas
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Date Joined Mar 2008
Total Posts : 4849
   Posted 1/20/2011 5:30 AM (GMT -6)   

Regular Member

Date Joined Dec 2010
Total Posts : 191
   Posted 1/20/2011 5:48 AM (GMT -6)   
steve n dallas, Bump? please explain. confused

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Date Joined Mar 2010
Total Posts : 1152
   Posted 1/20/2011 6:01 AM (GMT -6)   
Bump simply means that Steve is trying to get more attention to your post by bumping the post up the list.


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Date Joined Dec 2008
Total Posts : 3149
   Posted 1/20/2011 7:15 AM (GMT -6)   
Bumpy road-
I hope Ralph (in Arz.) re-answers your question his experiences would exceed mine in years and total knowledge. Anyway in my own serious case with PCa from early 2002 it took 4 months on ADT to reach my nadir (lowest) psa level while on just the drug(s). So, it can take more than three months in some patients, too many variables in PCa to classify things nice and simplistic...doesn't work that way. My Joe Blo guess is you have some independent PCa (hrpca) cells and the venue you are in is way over the head of the typical uro-doc. Dependending upon your choices, insurance, and things....if you can see the likes of Dr. Scholz, Lam, Myers, Sartor, Voglezang, Yu, Leibowitz and some other specialists it would be perhaps the best move you could my s.w.a.g. estimate opinion. Anyway as Dr. Strum mentions in his book, if you are a failed to be cured patient (in effect) you are beyond the skill sets of the typical urologist, (my thoughts)-they don't study the biology of PCa.  They typically only use maybe 3 drugs and may not even be totally versed in all aspects of monitoring even those. Did you read about other drugs used in PCa?  (proven treatments tab)

Post Edited (zufus) : 1/20/2011 5:20:43 AM (GMT-7)

Regular Member

Date Joined Mar 2010
Total Posts : 495
   Posted 1/20/2011 11:00 AM (GMT -6)   
If my high school chemistry is working upstairs, then you have a T level of approximately 14 on the N. American scale of nanograms/deciliter. This indeed indicates that the hormone reducing drug is working effectively. I assume you are on no other drug such as an anti-androgen like cyproterone acetate (CPA, Androcur), bicalutimide, or others. If the foregoing is true then in your case, as in mine, a lower psa is considered a better psa. More time may show a stronger response. An anti Androgen (A-A) could also show a result, if it is not currently used. DES, estradiol, and various other combinations are also available.
Much of our disease involves less projection of the future, however much I think I would like to be able to do so, and much more of taking things as they are. Your doctor cannot treat your disease as it may be, he must treat it as it is. This anxiety is one of the prices we pay for chronic conditions.
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