Update on Rodney (sclerotic lesions)

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Regular Member

Date Joined Jun 2007
Total Posts : 95
   Posted 1/19/2011 12:54 PM (GMT -6)   
Hi everyone:

I'm sorry that I only contact you when I need help. I find it difficult to participate on the forum because of the anxiety it produces for me. I hope that you would still be willing to help me.

My husband, Rodney, had his follow-up appointment with Henry Ford Hospital today. (I contacted the forum last September to share that Rodney's PSA was 177 and that the CT showed cancer where the prostate used to be and multiple enlarged lymph nodes. Rodney refused radiation three years ago. The radiation oncologist said he was not a candidate for radiation at this time because they felt the cancer was going to appear elsewhere in the body. The bone scan was negative.)

Rodney had a repeat PSA done on November 30 and a repeat CT done on December 8. We found out the results today when Rodney had an appointment with the radiation oncologist. The PSA is down to 1.1 and the CT scan shows a reduction in the cancerous mass and resolution of the multiple enlarged lymph nodes in one area and near resolution in another area. However, "attention to the sacrum demonstrates a 10mm sclerotic focus which is ringlike, this is significantly more sclerotic on the current exam and may represent a bone metastasis. There is also faint sclerosis along the superior endplate of T12 which may be discogenic in nature but may represent a second site."

The radiation oncologist sent Rodney for a back xray to further evaluate the above findings.

Rodney received his second 4-month Lupron injection today. The radiation oncologist is going to have a meeting with the other radiation oncologists to see if they now recommend radiation as well.

My question is: How could parts of the body improve with treatment but still possibly spread cancer? It seems like all areas would be affected by the treatment. Would those bone results be worrisome for all of you?

Thank you for all your kindness and help you have shown us since 2007.

Dearborn Heights, MI
Husband Rodney
Prostatectomy 2007
Gleason Score 9
Post-surgical PSA: 0.4 and rising
Refused radiation
PSA Sept. 2010: 177
Sept. 2010: Lupron injection

Elite Member

Date Joined Oct 2008
Total Posts : 25355
   Posted 1/19/2011 1:16 PM (GMT -6)   

Thanks for the update on Rodney. Can't answer any of your questions, but sure someone will around soon that can. Good continued luck to the two of you.

David in SC
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 Not taking it
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/23/10

Veteran Member

Date Joined Dec 2008
Total Posts : 3149
   Posted 1/19/2011 2:34 PM (GMT -6)   
Inside Dr. Strums book there are photo examples of bone mets person, and after HT therapies new scans showing the hot spots had gone away and were not visible(on scans)....shows the drugs can work on spread PCa...how much and how long it may keep it at bay is always the big question. Once PCa spreads to anywhere in your body, lung, brain, bone....it is always PCa and not some other cancer, so it can respond to various drugs, some refractive PCa cells (hrpca) become independent 'refractive' against drugs over time and sometimes other different drugs can work for decent time frames, this is why certain docs switch protocols trying to keep up with the refractive changes.

The radiation if done to bone spots like vertebrate is meant for alleviation of bone pain and perhaps control at that site, but they cannot radiate your whole body(to the level needed) and PCa can travel throughout the lymph system and end up about anywhere, usually prefers bone marrow areas after intial spread. They cannot detect tiny amounts of PCa, i.e. micro mets and that is a sorrowful thing for us patients. You might wish to see Dr. Forman on radiations here in Michigan, he is kind of reknown for this and has done many, many spot radiations also. Hope that answers some, Dr. Strums book with info: A Primer on Prostate Cancer (fyi). This oncology with PCa is very strange and never simplistic, some PCa specialists know the most about controlling it compared to others. I too am I Michigan guy.
Dx-2002 total urinary blockage, bPsa 46.6 12/12 biopsies all loaded 75-95% vol.; Gleasons scores 7,8,9's (2-sets), gland size 35, ct and bone scans look clear- ADT3 5 months prior to radiations neutron/photon 2-machines, cont'd. ADT3, quit after 2 yrs. switched to DES 1-mg, off 1+ yr., controlled well, resumed, used intermittently, resumed useage

Post Edited (zufus) : 1/19/2011 1:43:18 PM (GMT-7)

Veteran Member

Date Joined Nov 2009
Total Posts : 7187
   Posted 1/19/2011 2:39 PM (GMT -6)   
Just curious who your husband is consulting with at Ford.
I had my surgery done at Ford with Dr. Menon.
PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (PSAf: 24%), PCA3 =75 .
Biopsy 11/30/09. Gleason 4+3. Stage: T1C. Current Age: 64
Surgery: Dr. Menon @Ford Hospital, 1/26/10.
Pathology Report: G 4+3. Nodes: Clear. PNI: yes. SVI: No. EPE: yes. Pos. Margin: Yes-- focal-- 1 spot .5mm. 100% continent by 3/10. ED- in progress. PSA on 3/10/10-: 0.01. PSA on 6/21/10--0.02. 9/21/10--0.06; 1/4/11-0.13 CRAP!
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