My surgeon left benign prostate tissue behind on purpose with my surgery. His reasoning was that there were no signs that would indicate cancer outside the prostate and he wanted to seperate my prostate from my bladder without cutting into bladder tissue and causing damage. My post path report was very good with no signs at all of cancer outside the prostate with all margins negative.
At 3 months after my RP, my PSA was .06, at 6 months it went to .19. My surgeon/Uro felt very confident that the rise was from Benign prostate tissue starting to reconnect itself to my blood supply and adding PSA to my system. So to prove that this was the case, he put me on Avodart for 3 weeks and my PSA dropped to .154 and that is a pretty fast drop in a short time indicating substancial prostate tissue and proving his point.
We also discussed that this is not absoulute proof that there is not any cancer cells still present (he really doesn't think so) but to prove this out we need to establish a new PSA baseline. He took me off Avodart and we will let my PSA rise again and hopefully it will just level off, he thinks that will be around .2. So my next test in 3 months will show a rise to what should be my new baseline and then the next test 3 months later hopefully will be the same proving out my true baseline.
This all makes sense to me and I hope it proves itself out to be true. We also decided that if my PSA continues to rise that my trigger for SRT would be a PSA of .4 since we have proven that some of the total PSA count is coming from benign tissue.
I wonder how many guys have pulled the trigger for SRT at .2 when it was just benign prostate tissue causing the PSA rise ??
PSA: 5/05-2.008, 12/08-2.87, 2/11-4.357
3/11- 12 needle biopsy, 1 core positive GS 3+3
5/3/11- RP performed, tumor volume 1cc, pT2c all margins and lymph nodes negative
PSA: 8/1/11-.06, 10/26/11-.16, 10/31/11-.17, 10/31/11-.19
11/24/11- Started Avodart
PSA: 12/16/11- .154
12/22/11 Started Trimix
Post Edited (trimix) : 1/22/2012 1:49:15 PM (GMT-7)