24 Types of Prostate Cancer

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Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 2/8/2011 6:02 PM (GMT -6)   
This may be old news for some, and new news for others.  And Zufus, will give you early credit for the subject of mutiple types of PC.
 
Thought this link was interesting on the subject:
 

Piano
Veteran Member


Date Joined Apr 2008
Total Posts : 847
   Posted 2/9/2011 12:11 AM (GMT -6)   
Interesting article, especially the Wall Street Journal Link that I hadn't seen before.

I suspect that many of us will have a mixture of cancer types, just as we have a range of cell types that make up the Gleason scores. And many of us have a mixture of mostly hormone-sensitive cells, and often less of the ones that ignore hormones.

Just as hormone treatment can kill off all the sensitives and leave just the refractories, I expect that treatments aimed at the type of the cancer will eventually fail for the same reasons. But such treatment should buy us some more time...

I like the analogy of a lawnmower engine (the driver of the PCa) vs a BMW V12 engine. But I think the analogy falls down big-time, because it assumes that the lawnmower will never turn into a BMW -- with PCa can we be certain?

But I'd sure love to have a real lawnmower that did that :-)
No symptoms; PSA 5.7; Gleason 4+5=9; cancer in 4/12 cores
Non-nerve-sparing RRP 7 March 2008 age 63
Organ confined, neg margins. Gleason downgrade 4+4=8
Fully continent
Bimix worked well; now using just VED
PSA undetectable at first but now 0.4, doubling time 7 months
No radiation but ADT coming unless I can slow down the rise...

zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 2/9/2011 8:20 AM (GMT -6)   
Let's Deja Vu (D.J. View it one more time):

www.yananow.net/24Variants.pdf  

www.webpathology.com/case.asp?case=23        (photos of 18 variants)

Of course PCa is simplistic (LOL X 1000= OMG), then know that 3 ploidy DNA types exist in any one given PCa type. Anyone like statistics alot? Knowing these things should have you thinking a whole lot of questions and wonders about all the so called definity of PCa. How many experts know this or will discuss such a subject matter with the patient. Bueller.....Bueller...????

English Alf
Veteran Member


Date Joined Oct 2009
Total Posts : 2218
   Posted 2/9/2011 11:40 AM (GMT -6)   
Don't like the fact that I am from a family where melanomas occur!

That lawnmower analogy might also back fire if what counts when it comes to spreading
is the ability of the cancer to wiggle its way through small spaces. It might be more like
the difference between being hit by a large cushion or a small armour-piercing round!

Just off to ruin my diet by having a steak, but it's the first one in several months.

Alf

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4269
   Posted 2/9/2011 3:40 PM (GMT -6)   
See post that was bumped on 2-7 on negative psa by dan reinhart. It takes an experienced doctor to recognize these PC variations. Dan was lucky that he was a researcher and did his own research coming across an obscure Japanese study on his condition and contacted Dr Myers. I just wonder how many of these varients have gone unrecognized and resulted in patient's deaths and were just chalked up to a normal reoccurrance and treated as such.
JT
65 years old, rising psa for 10 years from 4 to 40; 12 biopsies and MRIS all negative. Oct 2009 DXed with G6 <5%. Color Doppler biopsy found 2.5 cm G4+3. Combidex clear. Seeds and IMRT, no side affects and psa .1 at 1.5 years.

English Alf
Veteran Member


Date Joined Oct 2009
Total Posts : 2218
   Posted 2/9/2011 3:54 PM (GMT -6)   
Just wondering how many variables for the type of disease, type of patient, type of treatment,
type of doctors, type of hosptial etc there are to put into the mathematical model to work
out what might happen, but it sure confirms my idea that this mess I'm in comes with an
infinite number of possibilities!

Think I'll just stick to trying to prove that E does not equal mc2

Alf

Jerry L.
Veteran Member


Date Joined Feb 2010
Total Posts : 3072
   Posted 2/9/2011 4:42 PM (GMT -6)   
I've read that adding 8 ounces of pomegranate juice to either the lawn mower or the BMW's fuel "may" cause the engine to stall.
Nov. 2009 Dx at Age 44
Dec. 2009 DaVinci Robotic Surgery
Jan. 2010 T3b, Gleason 9
Feb. 2010 Adjuvant Radiation

PSA History:
-----------------
Nov. 2009 4.30
Feb. 2010 <.05
May 2010 <.05
Aug. 2010 <.05
Nov. 2010 <.05
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