PSA on the rise

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tedgard
Regular Member


Date Joined Feb 2008
Total Posts : 104
   Posted 2/8/2011 9:25 PM (GMT -6)   

Well, went for my PSA checkup yesterday.  Over the last few times, it has gone from .00 to .01 to .02 to .04 to .12.  I know that .12 is still really low, but it has been rising up on each 6 month visit.

 

My Dr has set me up for meeting with the Oncologist on Thursday.  It looks like radiation therapy is in my near future.

 

I understand that there is a ~65% chance that with the radiation therapy will kill the bug.  Just hope I am in the 65% group versus the 35% group…


Diagnosis Results – Oct 31, 2007;
•Age – 53 (turned 54 in Nov 2007)
•PSA is 3.83
•Gleason's Grade - 3+3=6, T1C

Surgery Dec 11, 2007;
•Cancer confirmed on Right mid and Left apex
•Both nerve bundles spared, some damage to the Left bundle.
•30 day PSA, .01
•90 day PSA, .00
•Latest PSA, .04
•ED treatments: Levitra, Cialis, Trimix, Erect Aid pump, Penile Implant on 3/12/2009
•Happy

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 2/8/2011 9:32 PM (GMT -6)   
After being a "zero" for over 3 years, your rise to .12 is a good point to start talking to the oncologist, and get their take on it. Good luck, and hope the rise slows down for you.
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 Not taking it
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/23/10

tedgard
Regular Member


Date Joined Feb 2008
Total Posts : 104
   Posted 2/8/2011 10:52 PM (GMT -6)   

Purg,

Thank you for the response.

It appears that you have a close PSA history to mine.

I assume that the "Post SRT PSA" means the PSA results after having radiation treatments.  Is that correct?  So does that mean that your PSA has dropped in consecutive tests after having radiation?

Thanks,

Ted.


Diagnosis Results – Oct 31, 2007;
•Age – 53 (turned 54 in Nov 2007)
•PSA is 3.83
•Gleason's Grade - 3+3=6, T1C

Surgery Dec 11, 2007;
•Cancer confirmed on Right mid and Left apex
•Both nerve bundles spared, some damage to the Left bundle.
•30 day PSA, .01
•90 day PSA, .00
•Latest PSA, .12
•ED treatments: Levitra, Cialis, Trimix, Erect Aid pump, Penile Implant on 3/12/2009
•Happy

pasayten
Regular Member


Date Joined Mar 2007
Total Posts : 437
   Posted 2/8/2011 11:11 PM (GMT -6)   
tedgard,

Your numbers are very close to mine including the Gleason 6... After 32 months my PSA had risen to 0.13 and I went in for SRT. No hormones, just radiation. Probably due to the Gleason 6 less agressive PCa. I am near one year post SRT and at a PSA od 0.01... Great results and for me, no significant or long lasting side effects from the radiation. My first post SRT PSA was 0.02 and the second 0.01... Excellent results and actually quicker than expected. You can view my "extended signature" for more complete details.
3/2007 - Dx 59 y/o - 12 point biopsy - Left 0/6 Right 1/6 Gleason 3+3 T1c
4/2007 - DaVinci RRP performed - Gleason 6 T2c Nx Mx
PSA 7/07 0.01, 6/08 0.02, 12/08 0.03, 10/09 0.13
11/09 Consult BCR and rec for SRT
1/2010 IMRT SRT - 32 sessions 2 gys for 64 gys total.
6/2010 3 mth PSA post SRT 0.02
1/2011 10 mth PSA 0.01
My Extended Signature

ChrisR
Veteran Member


Date Joined Apr 2008
Total Posts : 825
   Posted 2/9/2011 6:30 AM (GMT -6)   
Sorry about your situation.
 
What were your post op stats?

Were you still G6 and organ confined? Did you have a positive margin or upgrade on Gleason score?
 
I think I noticed in one of your other posts that you had a nerve bundle removed.  Was it positive for PCa or just suspicious.  If so, were you still considered organ confined if the bundle was involved?
 
 

Post Edited (ChrisR) : 2/9/2011 6:30:52 AM (GMT-7)


tedgard
Regular Member


Date Joined Feb 2008
Total Posts : 104
   Posted 2/9/2011 12:29 PM (GMT -6)   

pasayten,

Thank you so much for the follow up.  I have gained good knowledge and hope from your post.  Looks like your results were great.  I am hoping for the same.

Chris R,

Here is some additional information, hope it is helpful, also check my signature for more details;

My PSA was .04 last time, but now it has been on the rise and is now at .12, as of yesterday.

I was also confused why I would have a PSA without a prostate.  It is my understanding that there are a few reasons why this can happen. Even though they are carful to remove all the prostate tissue, if they leave just a sliver, you could have an ongoing PSA in the “noise” range.

My Dr tells me that there are a number of things to consider for each individuals case before taking further action.

In my case, the PSA has been on the rise for at least the last three 6 month check PSA checkups .01, .02, .04 and now .12.  This has caused him to be concerned and he has set me up to see the Oncologist on Thursday for discussing radiation therapy.  I asked him if the PSA could be going up due to an infection or something. He informed me that this could have been the case before having a prostatectomy, but after having a prostatectomy over three years ago, the only reason for the rise in PSA that I am having is because there has to be some residual cancer.

In my case, because I am still considered on the younger side of the PC survivors group, he believes that he wants to take a more aggressive approach and try to stop the growth sooner rather than waiting until later on.  Because PC is so slow growing, I assume that if I were in my 80’s, even with this small rise in PSA, it may not be something to be overly concerned with.

Also, in my case, after my prostatectomy, the pathology report showed that all the margins were negative.  Regardless, because one of the nerve bundles was involved, the newer theories are that with the nerve involvement that the cancer cells can escape the prostate by traveling along the nerve.  This is the reason that in my case there is more concern with the rising PSA then it may be for others.

That is why I am expected to be going in for radiation therapy in the near future.  The expectation is that with the radiation therapy that there is ~65% chance that this will kill the cancer, or at least stop it from growing any further.

I hope this information is helpful.  I will provide an update after my visit with the Oncologist tomorrow morning.

Ted

 


Diagnosis Results – Oct 31, 2007;
•Age – 53 (turned 54 in Nov 2007)
•PSA is 3.83
•Gleason's Grade - 3+3=6, T1C

Surgery Dec 11, 2007;
•Cancer confirmed on Right mid and Left apex
•Both nerve bundles spared, some damage to the Left bundle.
•30 day PSA, .01
•90 day PSA, .00
•Latest PSA, .12
•ED treatments: Levitra, Cialis, Trimix, Erect Aid pump, Penile Implant on 3/12/2009
•Happy

Magaboo
Veteran Member


Date Joined Oct 2006
Total Posts : 1210
   Posted 2/9/2011 12:40 PM (GMT -6)   
Hi Ted. Sorry to hear about your rise in PSA, but you seem well prepared for the next step in your journey. I too had a recurrence about 2 years after RRP and had SRT a little over 2 years ago and I'm doing well thus far. Keeping my fingers x'd that you too will do well.
Good luck and all the best to you.
 
Mag

Born 1936
PSA 7.9, Gleason Score 3+4=7, 2 of 8 positive
open RP Nov 06, T3a, Gleasons 3+4=7, Seminal vesicles and lymph nodes clear
Catheter out 15 Dec 06, Dry since 11 Feb 07
All PSA tests in 2007 (4) <.04
PSA tests in 2008: Mar.=.04; Jun.=.05; Sept.=.08; at SRT Start=0.1,
Salvage RT completed (33 days-66Gy) 19 Dec 08
PSA: in Jan 09 =.05, all tests to date (Jan 11) <.04

jamarlyn
New Member


Date Joined Feb 2011
Total Posts : 1
   Posted 2/9/2011 3:12 PM (GMT -6)   
I'm really hoping someone on here can help me.

My father was diagnosed with prostate cancer 4 years ago. He has had surgery and follow up therapy afterwards. He's gone from monthly to 3 monthly implants and overall has kept very well. For a short while he did without the implants but a rise in his PSA prompted the doctor to start these again.

Over the last few months he's had problems urinating (one of his original symptoms) but the doctors felt that this was more to do with scar tissue from his earlier surgery rather than a problem with his prostate.

Last week he had further surgery to widen his "tube" as he calls it, and the flow is back to normal - unfortunately he had a call today with the results of a blood test taken last week and his PSA is 26 (previously 9)

I was wondering if a PSA level could increase as a result of surgery? It really knocks him for six when he gets news like this, especially when they just call to drop this bombshell but don't offer any explanation for the sudden rise. He has a hospital appointment next week but I know he's going to be distraught and depressed until he goes there. I'd like to be able to offer him some alternative reasons for this increase but don't know enough about it to do that.

Help....please....

tedgard
Regular Member


Date Joined Feb 2008
Total Posts : 104
   Posted 2/9/2011 7:10 PM (GMT -6)   
Hi jamarlyn,

First, let me tell you that I am very sorry to hear about your father's diagnosis.

I believe that you may want to post this at the site as a standalone new topic. I think that that may result in more responses versus at the bottom of this thread. There are a lot of other participants that may have some good information for you. They may not see it here.

I wish I could provide some feedback, but this post leaves me with more questions than the ability to provide a response.

Ted.
Diagnosis Results – Oct 31, 2007;
•Age – 53 (turned 54 in Nov 2007)
•PSA is 3.83
•Gleason's Grade - 3+3=6, T1C

Surgery Dec 11, 2007;
•Cancer confirmed on Right mid and Left apex
•Both nerve bundles spared, some damage to the Left bundle.
•30 day PSA, .01
•90 day PSA, .00
•Latest PSA, .12
•ED treatments: Levitra, Cialis, Trimix, Erect Aid pump, Penile Implant on 3/12/2009
•Happy
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