Tesetaxel ~ Oral Chemotherapy

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Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 2/10/2011 4:21 PM (GMT -6)   
Genta is entering their newest drug Tesetaxel into a phase II evaluation. Tesetaxel is an oral taxan that just my reduce many of the morbid side effects of chemotherapy. Here is the information from the InfoLink:

prostatecancerinfolink.net/2011/02/10/oral-taxane-enters-phase-ii-clinical-trial-for-mcrpc/

I certainly hope this pans out. Todays front line chemotherapy, docytaxel (Taxotere) and prednisone, offers a median of 19 months life extension but has many side effects. Then we have a second line chemo Cabazitaxel (JEVTANA) that is also combined with a steroid (prednisone) that can deliver an addition median of 4 months life extension. Both of these options are riddled with various side effects. It would be great to reduce these to a prescription that does not require a steroid.

Stay tuned.

Tony
Advanced Prostate Cancer at age 44 (I am 48 now)
pT3b,N0,Mx (original PSA was 19.8) EPE, PM, SVI. Gleason 4+3=7

Treatments:
Da Vinci Surgery ~ 2/17/2007
Adjuvant Radiation Therapy ~ IMRT Completed 8/07
Adjuvant Hormone Therapy ~ 28 months on Casodex and Lupron.
Undetectable PSA.

Blog: www.caringbridge.org/visit/tonycrispino
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