Dx Stories with PSA 10-20 Range

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K2
Regular Member


Date Joined Feb 2011
Total Posts : 51
   Posted 2/17/2011 2:22 PM (GMT -6)   
I'm looking for outcomes from folks with similar PSA numbers as myself (PSA 12.76, 51yrs old) I haven't read too from this demographic.
 
I think I perfer the surgery option but some folks say once the PC is beyond the gland it's pointless (I think they mean not cureative). I've read outcomes for locally confined PC with surgery followed by RT are better than RT alone.
 
Experiences?
 

BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 2/17/2011 2:59 PM (GMT -6)   
you should check out yananow

Fairwind
Veteran Member


Date Joined Jul 2010
Total Posts : 3741
   Posted 2/17/2011 3:16 PM (GMT -6)   
www.yananow.org/Experiences.html#pb

I was PSA 7 on Proscar so that's really PSA 14..Gleason 9. Chances with surgery 50-50..I took those odds. Surgery failed. just completed SRT and am on hormones. PSA undetectable at this point..

Many doctors feel that surgery, while it might / probably will fail, reduces the tumor volume to very low levels and gives radiation and ADT a much better chance of working...

It should be noted that this treatment path also extracts the maximum amount of money from the patient..
Age 68.
PSA age 55: 3.5, DRE normal.
age 58: 4.5
61: 5.2
64: 7.5, DRE "Abnormal"
65: 8.5, " normal", biopsy, 12 core, negative...
66 9.0 "normal", 2ed biopsy, negative, BPH, Proscar
67 4.5 DRE "normal"
68 7.0 3rd biopsy positive, 4 out of 12, G-6,7, 9
RALP Sept 3 2010, pos margin, one pos vesicle nodes neg. Post Op PSA 0.9 SRT, HT. 2-15-'11 PSA 0.0

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3732
   Posted 2/17/2011 3:19 PM (GMT -6)   
Hey K2,

Here are my stats. DaVinci 18 months ago.
Results: Except for ED I'm fine, now. The incontinence was fixed with an AdVance sling.

Yananow has a big database that you can sort on PSA.
You'll find you really are not alone.

Jeff
Age: 58, Mar 35 yrs, 56 dx, PSA: 4/09 17.8 6/09 23.2
Biopsy: 6/09 7 of 12 Pos, 20-70%, Gleason 4+3 Bone, CT Neg
DaVinci RP: 7/09, U of Roch Med Ctr
Path Rpt: Gleas 3+4, pT3aNOMx, 56g, Tumor 2.5x1.8 cm both lobes and apex
EPE present, PNI extensive, Sem Ves, Vas def clear, Lymph 0/13
Incont: 200ml/day ED: Trimix
Post Surg PSA: 10/09 .04, 4/10 .04, 7/10 <0.01, 12/10 <0.01
AdVance Sling 1/10/11

Kark60
Regular Member


Date Joined Jun 2008
Total Posts : 91
   Posted 2/17/2011 3:27 PM (GMT -6)   
I more or less fit your situation. I chose surgery and PSA stayed at 0.0, then went to 0.1 and stayed for several months, then went to 0.15 and was .3 when I started salvage radiation. I don't regret the surgery decision because I was thought to be "Stage 2" when I went into surgery, but came out with "Stage 3," meaning I had extra-capsular extension.

My understanding is if the cancer has spread beyond the capsule it still MIGHT be curative. All of this depends on the surgeon taking a wide-enough margin and/or some type of radiation treatment after surgery.

However, I would suggest you take some time and talk with BOTH a surgeon AND a radiation oncologist about your specific numbers, biopsy report, and other test results.
Diagnosed at 47 (currently 50). Pre-surgery PSA: 13.7 Pre-surgery Gleason: 4+3=7. CT Scan, Bone Scan, PET Scan: Clear. LRP 5/28/08. Left nerve bundle removed. POST-SURGERY: Gleason: 4+3=7; 10% of prostate all quadrants involved; EPE left base & apex; extensive PNI present. Bladder neck, lymphvasular space, seminal vesicles, 17 examined lymph nodes, and all surgical margins FREE of tumor. T3a. Four-week post-surgical PSA = 0.1; Seven-week = .01; 10/08 – 4/10 PSA= 0.0; 4/10=0.1; 5/10 & 8/10 = 0.1; 9/10=.15; Prostiscint = negative; 12/10=0.3. 12/15/10 began 70.2 grays SRT and will finish 10/10/11.

Newporter
Regular Member


Date Joined Sep 2010
Total Posts : 225
   Posted 2/17/2011 3:28 PM (GMT -6)   
Look at my signature. PSA was increasing quite rapidly and if I waited another year, would have been much higher than the 10.7 at diagnosed.
65 Dx June-2010 PSA: 10.7, biopsy: Adenocarcinoma, 1 core Gleason 6, 3 cores atypia; Clinical stage T2; CT, Bone Scan, MRI all negative

8-23-10 Robotic RP; Pathology: Negative margins; Lymph nodes, Seminal Vesicle clear; PNI present; multiple Adenocarcinoma sites Gleason 3+3 with tertiary Gleason 4+. Stage: pT2,N0,Mx,R0

Catheter out 8-30-10 no incontinence, no ED. 1/2011 PSA: <.1

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 2/17/2011 4:20 PM (GMT -6)   
Went into surgery with PSA of over 16, Gleason 7. Came out with Gleason 7 and Stage II, had fairly fast BCR - less then a year, and now awaiting final answer on whether the SRT worked for me or not. You never know what you are going to get.
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 11/10 Not taking it
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/23/10

Gunner59
Regular Member


Date Joined Nov 2008
Total Posts : 109
   Posted 2/17/2011 6:31 PM (GMT -6)   
You can see my stats in my sig, PSA near 30 before surgery,no radiation, and still clear after 2.5 years. I seem to be in the minority however.
Age 48 at diagnosis
3 Jul 08 PSA 27.21
Biopsy positive 3+3=6 on 9 of 24 punches
Bone scan clear
22 Sep 08 Laproscopic Radical Prostatectomy and bilateral pelvic Lymphadenectomy
Gleason 3+4=7 after prostate removal, lymph nodes clear
Stage T2B
PSA at 3 months=undetectable
6 month PSA still 0
14 Sep 09 PSA < .014
18 Mar 10 < .014
3 Sep 10 < .014
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