Bone Scan, MRI, CT Scan

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Jerry L.
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Date Joined Feb 2010
Total Posts : 3072
   Posted 3/10/2011 6:19 PM (GMT -6)   
As indicated in my recent post, latest PSA up to .09 from undetectable (I really disklike typing that last sentence).
I've had lower back / hip pain on and off for the last year.  In June, bone scan came back ok.
Fast forward to now - depending on the next PSA, docs may want to do a bone scan or MRI and probably recommend ADT.
1)  Which is more sensitive of a test? 
2)  I suppose bone scan checks bone and MRI checks soft tissue?
3)  One of my friends told me that his oncologist (very reputable) finds that if PC comes back, it is usually is in the lymph nodes near the back.  He sends his patients to Sand Lake Imaging in Orlando where they use a MRI that uses a contrast agent that consists of nano-particles of iron oxide which can find sites as small as 2mm.  Thoughts on this?   Ever heard of this type of MRI?
Nov. 2009 Dx at Age 44
Dec. 2009 DaVinci Robotic Surgery
Jan. 2010 T3b, Gleason 9
Feb. 2010 Adjuvant Radiation

PSA History:
Nov. 2009 4.30
Feb. 2010 <.05
May 2010 <.05
Aug. 2010 <.05
Nov. 2010 <.05

Veteran Member

Date Joined Dec 2008
Total Posts : 3149
   Posted 3/10/2011 7:03 PM (GMT -6)   
Jerry the USPIO used in Florida by Dr. Bravo is the recent buzz in the closest thing available to Combidex (Netherlands, currently not operating still??). The FDA here in the USA did not approve Combidex (Ralph Blum in Dr. Scholz book was present at the FDA approval meetings..great info on that in the book-fyi).

One of the guys on PPML went to Sand Lakes after other MRI and such scans did not find PCa, this machine and method did find lymphnode envolvement and I think the info is going to be given to Dr. Dattoli to proceed with that guys radiation protocol, going forward. So, keep that one in mind.

In other scans you need approx. 1-billion cells or so in order to show up on a scan...micro mets goes undetectable is the message on that. Study all you can. You have lots of choices in PCa.

Regular Member

Date Joined Nov 2009
Total Posts : 486
   Posted 3/10/2011 8:05 PM (GMT -6)   
Jerry,  The contrast agent you are refering to is Feraheme.  It was recently approved for treating chronic kidney disease and nothing else.  As zufus mentioned, DR. Bravo is using it off label as a contrast agent (similar to combidex).  Dr. Myers talked about it in one of his videos but I don't have the link.  Dr. Myers believes it accurately identifies lymph node involvement.  The question I have is what difference does it make for PSA relapse after SRT?  None of the scans can rule out occult bone mets.  I will be very interested in what you learn from your doctor on your next visit.
Dx 2/2008, age 71, PSA 9.1, G8,T1c. daVinci surgery 5/2008, G8(5+3), pT2c. LFPF, good QOL. PSA <0.1 for 2 yrs. PSA rose to .2 at 30 months, Completed SRT 2/2011. PSA 0.1 at 3 wks post SRT.
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