Update to 6 month Avastin trial

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duke68
Regular Member


Date Joined Mar 2007
Total Posts : 243
   Posted 3/12/2011 11:05 AM (GMT -6)   
Hi,

I've reached the half way point on the stage 2 trial for biochemical recurrence after definitive primary treatment failure. Avastin plus cab (lupron + Casodex ).

The usual ht (hormone therapy) symptoms in my case fatigue, memory, losing train of thought, emotions. No hot flashes so far.

This is my second time on 6 months of cab (combined Androgen blockade).

My present psa is 0.02 :)

How the Avastin effected the psa drop is unknown.

Trial stops the end of May then compare the 2 arms on length of time till bcr.

I sincerely hope this leads to a prolonged remission and the Avastin contributes to it.
It may lead to another treatment for this stage of the disease.

Best wishes to all

Gerry
Gerry
age 68 diag. oct 2006 G8 T2b psa 11.7
4 of 8 cores 20% 30% 60% 100%
rrp dec 2006 G9 4+5 m+ sv+ ece after 6 weeks psa 0.6 second opinion Dana-Farber pT3b 4+4 + T5 = G9
Rt 35 sessions to lymph nodes and prostrate 4-2007
3/2007 cab 6 months lupron + casodex.
psa <0.1 from june 2007 to march 2010
psa 6/10 0.3 9/10 0.6 12/10 2.5 :(

Dana- Farber Phase 2 trial Avastin Lupron and casodex

ralfinaz
Veteran Member


Date Joined Jan 2011
Total Posts : 735
   Posted 3/12/2011 11:13 AM (GMT -6)   
Hi Gerry,
Glad to see you are responding to Avastin added to ADT2. Can you tell us the frequency and dose of Avastin? Keep us informed.

Wish you the very best outcome!

RalphV
Phoenix, Arizona
Surviving prostate cancer since 1992. RP; Orchiectomy;
GS (4 + 2); bilateral seminal vesicle invasion; tumor attached to rectal wall. Last PSA September, 2010: <0.1 ng/ml
Laughter is the best medicine!

duke68
Regular Member


Date Joined Mar 2007
Total Posts : 243
   Posted 3/12/2011 11:48 AM (GMT -6)   
Hi RalphV

Treatment frequency is 8 iv's 3 weeks apart.
15mg/kg (of weight)
I had no reaction to the iv, or other than very minor nose bleeds any other side effects

Thanks for the best wishes.
I really hope this leads to another treatment for BCR only with no other symptoms.


Gerry
Gerry
age 68 diag. oct 2006 G8 T2b psa 11.7
4 of 8 cores 20% 30% 60% 100%
rrp dec 2006 G9 4+5 m+ sv+ ece after 6 weeks psa 0.6 second opinion Dana-Farber pT3b 4+4 + T5 = G9
Rt 35 sessions to lymph nodes and prostrate 4-2007
3/2007 cab 6 months lupron + casodex.
psa <0.1 from june 2007 to march 2010
psa 6/10 0.3 9/10 0.6 12/10 2.5 :(

Dana- Farber Phase 2 trial Avastin Lupron and casodex

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7270
   Posted 3/12/2011 1:06 PM (GMT -6)   
Duke:
 
Can you drop me an email. I'd like to chat if possible.
 
Mel
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