Mystery of Prostate Diseases Possibly Unraveled - Renal & Urology news.

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Regular Member

Date Joined Jun 2010
Total Posts : 416
   Posted 3/22/2011 7:27 AM (GMT -6)   
Hi Folks...I was reading a reply to my last post related to sperm and scrotum stuff when my Google News update came in... two articles that may be of interest to folks:
1) VIENNA—Benign prostatic hyperplasia (BPH) and prostate cancer could be the result a previously unrecognized route of free testosterone flow from the testes to the prostate, according to investigators.

The underlying cause, they say, is varicocele, which in turn is the result of a malfunction of one-way valves in the testicular venous drainage system, a phenomenon that exists only in humans.


2) VIENNA—Real-time elastography has significantly better predictive accuracy for identifying prostate cancer (PCa) lesions compared with contrast-enhanced magnetic resonance imaging (MRI), researchers reported here at the 26th Annual Congress of the European Association of Urology.


Good thoughts towards each of you !


Regular Member

Date Joined Sep 2010
Total Posts : 309
   Posted 3/22/2011 11:55 AM (GMT -6)   
That was very interesting. My husband WAS diagnosed with a varicocele, but fairly recently. Since researchers believe that PCa is present ten or so years before diagnosis, I had never made any connection. It is possible, of course, that the varicocele had also been present long before detection.

Have any of the rest of you experienced this?

Thanks for posting, Bob.


Veteran Member

Date Joined Jul 2006
Total Posts : 686
   Posted 3/23/2011 12:34 AM (GMT -6)   
This article and my subsequent research has raised some interesting questions about my own condition.  When I was thirteen (13) years old my physician/surgeon diagnosed and performed surgery on me for  condition the he described as a 'hydrocele'.  He said, if I recall, that is was on opening left when the testes descended after birth. An incision was made in the testicle sack and apparently the opening was closed.
I noticed as I became an adult that I had lumpy testicles with one teste smaller than the other and one that hung much lower than the other. In addition I have always felt that they were easily able to feel pain. I assumed the doctor of my youth had not done a good job on the surgery.    I had no basis to compare with other men, so I guessed that my testes were sort of normal.  No physician ever remarked that it was abnormal.  I even had an ultrsound of the testicles once to check an infection.  No abnormality was noted.  I went on to father two wonderful children. After the birth of my children,  I had a vasectomy performed and no comment was made. When I was diagnosed with prostate cancer I asked my urologist if my 'lumpy' testes were unusual and never got an answer.
Now I read that I might have and still do have a condition called 'varicocele.  I appears to be close in nature to the 'hydrocele' that a was treated for as an adolescent.  From the article, I can't figure if there is or is not a correlation between varicocele and prostate cancer.  I hope I can get more information.
PSA July 2006 4.7 , Nodule found
biopsy 10/06 very agressive gleason4+4=8 identified
DaVinci surgery, January 2007
Post Ob confirms, gleason 4+4=8 with no extension or invasion
no long term continence problems
post surgery PSA continues to be undetectable at 4 years
ED problems continue, using bimix
born 1941

Post Edited (lifeguyd) : 3/22/2011 11:38:52 PM (GMT-6)

Regular Member

Date Joined Nov 2009
Total Posts : 212
   Posted 3/23/2011 6:22 AM (GMT -6)   
One nut hanging lower than the other is normal. But the lumpiness might have been a sign, as it sounds like this condition is essentially varicose veins in the testes area, which can result in lumpy/mushy veins..
Interesting article.
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